Navigation Links
Chimerix Commences CMX001 Open-Label Clinical Study for the Treatment of Patients With Life-Threatening or Serious dsDNA Viral Infections
Date:1/7/2011

RESEARCH TRIANGLE PARK, N.C., Jan. 7, 2011 /PRNewswire/ -- Chimerix, Inc., a pharmaceutical company developing orally-available antiviral therapeutics, today announced that patient enrollment has begun in a multicenter, open-label clinical study of CMX001 (the CMX001-350 study) for the treatment of life-threatening or serious conditions caused by double-stranded DNA (dsDNA) viruses.

Under the expanded-access protocol developed in conjunction with the U.S. Food and Drug Administration (FDA), patients will receive treatment with CMX001 for any of 12 different dsDNA viral infections, including adenovirus (AdV), herpes viruses (cytomegalovirus (CMV), herpes simplex virus (HSV) and Epstein Barr virus), polyoma viruses (BK virus and JC virus), and pox viruses.  The CMX001-350 study will enroll 200 patients at major medical centers primarily in the United States.

CMX001 is being developed by Chimerix for dual-use as a broad-spectrum antiviral for the treatment of life-threatening viral infections in immunocompromised patients and as a medical countermeasure in the event of a smallpox outbreak.  Chimerix is currently conducting a Phase 2 dose-defining clinical study of CMX001 in immunocompromised hematopoietic stem cell transplant patients at risk of life-threatening infection with CMV, which has enrolled over 130 patients. Additionally, the Company is initiating a Phase 2 clinical study in immunocompromised pediatric and adult hematopoietic stem cell transplant patients with AdV infections.

"Data from this open-label clinical study will be a critical component of our strategy to develop CMX001 as a broad-spectrum antiviral agent," said Kenneth I. Moch, President and CEO of Chimerix.  "We anticipate that the CMX001-350 study will provide important supportive data for our overall clinical development program."

"CMX001 is exhibiting a favorable tolerability profile and signs of potent antiviral activity across our clinical studie
'/>"/>

SOURCE Chimerix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Chimerix Initiates a Multi-dose Clinical Trial of the Companys Lead Compound, CMX001, for the Treatment for Smallpox Infection
2. Chimerix Updates the World Health Organization and the Global Health Security Initiative on Development of CMX001 as a Broad-Spectrum Therapeutic for Smallpox
3. Chimerix to Present at Two Upcoming Investor Conferences
4. Chimerix CEO George Painter, Ph.D., to Speak on Improving Biodefense Product Discovery and Development Strategies at Institute of Medicine Workshop
5. Chimerix Initiates Phase 2 Study of CMX001 in Stem Cell Transplant Recipients Seropositive for Cytomegalovirus
6. Chimerix Appoints Thomas Pitler, Ph.D., Vice President, Business Development
7. Chimerix to Present at 9th Annual BIO Investor Forum
8. Chimerix Reaffirms Its Commitment to CMX001 as a Medical Countermeasure for Smallpox and Broad-Spectrum Antiviral Agent
9. Chimerix to Present at the Lazard Capital Markets 7th Annual Healthcare Conference
10. Chimerixs Antiviral CMX157 Demonstrates Positive Phase 1 Clinical Results With Favorable Pharmacokinetics, Safety and Tolerability
11. Memory Pharmaceuticals Commences Phase 1 Clinical Program for R4996/MEM 63908
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... N.C. , May 24, 2013  Regulatory ... the forefront of many organizations, priority list. ... medical device sectors understand a strong Medical ... challenges in clinical development, market education , ... to create a vital bridge between an organization ...
(Date:5/24/2013)... FRANKLIN LAKES, N.J. , May 24, 2013  BD ... leading global medical technology company, announced today that it will ... Care Conference on Thursday, May 30, 2013, at 10:40 a.m. ... can be accessed from the BD corporate website at ... June 6, 2013.    About BD ...
(Date:5/24/2013)... , May 24, 2013 /PRNewswire-iReach/ -- Phoenix Houses ... non-profit substance abuse services organization, is hosting its tenth ... Hills Hotel on June 6, 2013.  More than 300 ... funds for the adolescent residential treatment centers, family therapy, ... honor individuals whose accomplishments have positive influences on the ...
Breaking Medicine Technology:Building Medical Affairs Capabilities to Ensure Organizational Success across Key Operational Areas 2Phoenix House Honors Allergan Chairman David Pyott And Legendary Sports Agent And Humanitarian, Leigh Steinberg 2Phoenix House Honors Allergan Chairman David Pyott And Legendary Sports Agent And Humanitarian, Leigh Steinberg 3
... 31, 2011  PLC Systems Inc. (OTCBB: PLCSF), a ... device-based technologies, today announced that its new product, ... Disease and Contrast Nephropathy, a 90 minute ... November 7-11, 2011 in San Francisco, California.  ...
... 31, 2011 /PRNewswire-Asia-FirstCall/ -- China Sky One Medical, Inc. ("China ... ), a leading fully integrated pharmaceutical company in the People,s ... a conference call at 9:00 a.m. Eastern Time (ET) on ... 2011 financial results. A full version of the Company,s quarterly ...
Cached Medicine Technology:PLC Systems' RenalGuard® to be Featured in Chronic Kidney Disease and Contrast Nephropathy Session at TCT 2011 2PLC Systems' RenalGuard® to be Featured in Chronic Kidney Disease and Contrast Nephropathy Session at TCT 2011 3PLC Systems' RenalGuard® to be Featured in Chronic Kidney Disease and Contrast Nephropathy Session at TCT 2011 4China Sky One Medical Announces Conference Call to Discuss Third Quarter 2011 Results 2
(Date:5/24/2013)... NY (PRWEB) May 24, 2013 ... Commerce VP, Brandon Huff as Executive Vice President of ... commerce business units, which represented a large portion of ... digital growth as Dwell develops a fully-integrated commerce unit ... decade of experience monetizing digital content for leading firms ...
(Date:5/24/2013)... 2013 6Webs.com has educated thousands of ... home security monitoring provider. The easy to ... useful resource consumers prefer for unbiased and impartial home ... of the leading wireless home security system providers in ... on a number of key factors including reliability, technology ...
(Date:5/24/2013)... York (PRWEB) May 24, 2013 ... is a leading nationwide sales, installation and ... both consumer and commercial applications. The company’s core ... lifts, vehicle lifts for mobility devices, pool lifts, ... 101 Mobility operates over 30 locations, primarily through ...
(Date:5/24/2013)... 23 May 2013, Paris, France: Routinely measuring fractional ... coronary angiography for diagnosis of chest pain leads ... in four patients, according to results from a ... (Does routine pressure wire assessment influence management strategy ... study was designed to assess whether routine assessment ...
(Date:5/24/2013)... In a coup that surely made other Palm ... the Estetica Institute of the Palm Beaches performed eye surgeries ... morning show, “The Mo & Sally Morning Show.” The DJ’s ... with the results, giving Dr. DeLange and the team at ... Gardens, very valuable free publicity. , Dr. DeLange, the owner ...
Breaking Medicine News(10 mins):Health News:Yahoo Commerce Head Joins Leadership at Dwell Media 2Health News:2013 Best Wireless Security System Providers Reported by 6Webs.com 2Health News:Cortec Closes Equity Transaction with 101 Mobility 2Health News:Diagnostic coronary angiography: Functional flow reserve changes decisions in 25 percent of cases 2Health News:Dr. Greg DeLange of the Estetica Institute Recently Performed Eye Surgery on Both Members of Popular Morning Radio Team 2
... as eunuchs, can now choose a gender of their liking ... //to a special procedure developed at the All India Institute ... 1,100 patients have already given proper gender identities as males ... life, doctors at the premier research and referral institute said. ...
... looking at lactate with a much more positive eye, ... in the immediate //hours after a traumatic brain injury ... right, it could change how emergency room physicians and ... the first critical hours after injury. ,Previous ...
... technology that can quickly screen all 20,000-plus human genes for ... affect how sensitive human cancer cells are to certain chemotherapy ... in the April 12 edition of the journal Nature, researchers ... library of small RNA molecules – the first used by ...
... With allergy season in full bloom, the American Academy of ... of what you can do to cope with the pollen ... specialist can help. // ,This spring, pollen from blooming ... 45 million Americans, causing itching eyes, sneezing, nasal stuffiness, nasal ...
... in erectile dysfunction, decreased libido, anemia, sarcopenia, memory loss, ... ,While a low serum testosterone level is well-known for ... overall physical functioning and fall risk has not been ... of the Archives of Internal Medicine, Orwoll and colleagues ...
... of Queensland men have never been screened for prostate, colorectal ... ,Screening for colorectal cancer currently has stronger scientific evidence for ... skin cancer, but a new study in the Medical Journal ... colorectal cancer test than the other two. ...
Cached Medicine News:Health News:New Procedure Paves Way for Eunuchs to Choose a Gender and Conceive 2Health News:Study Challenges Conventional Treatment of Traumatic Brain Injury 2Health News:Gene Screening Points Way to More Effective Chemotherapy 2Health News:April Showers Bring May Flowers – And Plenty of Pollen, To 2Health News:Low Serum Testosterone Levels Associated With Fall Risk in Elderly Men 2
... 10% Ash: 1.6% ... Gel pH (1.5%): 5.0 7.0 Gel Point ... 95C A (430 nm, 1.5%): 0.150 ... 25,000 Ohms EEO (-m r ): ...
... incubators is available, ensuring the customers to ... specific requirements. miniTHERM incubators have a capacity ... space saving. Their size corresponds approximately to ... to stack up to three units on ...
... range of miniTHERM incubators is available, ensuring ... solution for their specific requirements. miniTHERM incubators ... compact and extremely space saving. Their size ... It is possible to stack up to ...
DH Autoflow Single Chamber Stackable Air-Jacketed CO2 Incubator...
Medicine Products: