Navigation Links
Children's Hospital Receives Six-Year Federal Contract to Study Antibiotic Use in Children With Urinary Tract Infections
Date:9/10/2009

--Will Shorter Treatments Reduce Drug Resistance?--

PHILADELPHIA, Sept. 10 /PRNewswire-USNewswire/ -- In the largest study of its kind, pediatric researchers at The Children's Hospital of Philadelphia have received a federal contract for a project to determine the most beneficial method of using antibiotics to treat urinary tract infections (UTIs) in children.

The award, announced September 2 by the National Institute of Allergy and Infectious Diseases (NIAID), aims to answer key questions about the best use of antimicrobial drugs against UTIs, the most common disorder of the kidneys and urinary tract in early childhood. UTIs are highly treatable, but an infection that goes untreated may lead to serious kidney damage.

Because widespread antibiotic use has allowed bacteria to evolve strains that are resistant to common drugs, the new study will investigate whether using antibiotics over a shorter period than the standard 10 days is an effective treatment, while reducing the risk of drug resistance.

The initial award is for $1.5 million, with total funding of $13.8 million available over the project's six-year duration if clinical trial milestones are met. Theoklis Zaoutis, M.D., M.S.C.E., an infectious diseases specialist at the Center for Pediatric Clinical Effectiveness at The Children's Hospital of Philadelphia, is the principal investigator of the NIAID study. The clinical trial will enroll 700 children at two centers -- the Children's Hospital of Philadelphia and the Children's Hospital of Pittsburgh.

It will be the largest clinical trial to compare a short course versus the standard course of antimicrobial treatments for UTIs in children, said Zaoutis.

"Our goals will be to determine the optimal duration of antimicrobial treatment for UTIs," added Zaoutis. "This information will allow doctors t
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. MedImmunes Motavizumab Reduced RSV Hospitalizations by 83 Percent Among High-Risk Native American, Full-Term Infants in Placebo-Controlled Phase 3 study
2. Gilbert Hospital Continues Cutting Edge Treatments
3. Siemens Preclinical Imaging System Helps The Methodist Hospital in Houston Further Its Research Mission
4. New Data Show Doripenem as Effective as Commonly Used Therapies in Treating Hospital-Acquired Pneumonias
5. AspenBio Pharma Reports Strong Results with Appendicitis Triage Blood Test from Large Multiple Hospital Study
6. INVEGA(TM) Significantly Reduced Symptoms of Schizophrenia Compared to SEROQUEL(R) in Acutely Ill, Hospitalized Patients
7. Cardinal Health Releases New Tool to Combat MRSA Infections in Hospitals
8. Hospital to Hold MRSA Briefing for Media and Community Leaders
9. Arizona Heart Hospital Reaches Settlement Regarding Clinical Research Matter
10. Providence Hospital Study Finds Communication System Leads to Faster Heart Attack Treatment
11. Allegheny General Hospital Performs First Liver Transplant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... Aug. 28, 2015 ... the addition of the "Investigation Report on ... offering. Originally discovered by Welfide (Mitsubishi ... Industries, Ltd) as an inflammatory drug, pranoprofen was ... Co., Ltd under the trade name of pranopulin ...
(Date:8/28/2015)... , Aug. 28, 2015 ... addition of the "Investigation Report on China,s Tobramycin ... Tobramycin is a traditional antibiotic whose eye drop and ... treatment of potential infection or inflammation caused by eye ... are able to produce tobramycin, among which ...
(Date:8/28/2015)... , Aug. 28, 2015 ... announced the addition of the "Investigation Report ... their offering. Developed by AstraZeneca plc, ... an important drug for the treatment of schizophrenia. ... quetiapine was listed in the Catalogue of Drugs ...
Breaking Medicine Technology:Investigation Report on China's Pranoprofen Market, 2010-2019 2Investigation Report on China's Tobramycin Market, 2015-2019 2China Quetiapine Market Investigation Report 2010-2019 2
... Genomics announced today that,the company entered into a ... (JHU) to commercialize products that identify,patients at risk ... a suite of,issued and pending JHU patents covering ... (IGF2). Orion,s simple blood-based risk,assessment test is being ...
... , - Data Published in the British ... Negative Impact on Overall Survival or Tumour,Progression, ... controlled,studies in 2,301 cancer patients shows that treating ... on survival, tumour,progression or deaths caused by blood ...
Cached Medicine Technology:Orion Genomics Gains Exclusive Worldwide Rights to the IGF2 Gene for Colorectal Cancer Risk Testing Through Licensing Agreement With Johns Hopkins University 2New Meta-Analysis Confirms Safety Profile for NeoRecormon in Treating Anaemia in Cancer Patients 2
(Date:8/30/2015)... Fl (PRWEB) , ... August 30, 2015 , ... ... Executive Vice President Jeff Fernandez will lead the expansion of global cosmeceutical and ... and skin care experience having spent the last 25 years working in operations, ...
(Date:8/29/2015)... ... August 30, 2015 , ... Rio Salado College President ... the college’s Vice President of Strategic Initiatives and Information Services. O’Shea, who has served ... college expand its reach and impact through innovative technologies and strategies. , “I am ...
(Date:8/29/2015)... ... August 29, 2015 , ... On Saturday, September 19, ... Applied Research Foundation (Meso Foundation) will present an educational program titled “Asbestos and ... and lasts through 9:30 PM (doors open at 6:45pm) at Calvary United Methodist Church, ...
(Date:8/29/2015)... ... August 29, 2015 , ... ... extend and improve the lives of patients, according to a newly published report. ... to read the full article. , The authors of the new paper ...
(Date:8/29/2015)... York, NY (PRWEB) , ... August 29, 2015 , ... ... unofficial end of summer (which astronomically, officially ends on September 22nd this year). For ... summer-induced cyber security hangovers linger on which could prove far more costly than a ...
Breaking Medicine News(10 mins):Health News:NPI Executive Vice President Leads Cosmeceutical Expansion 2Health News:Rio Salado College Appoints New Vice President of Strategic Initiatives and Information Services 2Health News:Mesothelioma Applied Research Foundation to Hold Educational Class About Asbestos and Mesothelioma Prevention 2Health News:Top Mesothelioma Researchers Highlight Targeted Therapies in New Report, According to Surviving Mesothelioma 2Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 2Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 3Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 4
... of North Carolina at Chapel Hill School of Medicine ... large clinical study to evaluate the role played by ... study, which was part of the Johnston County Osteoarthritis ... who inherited a specific pattern of genetic variations in ...
... sunless tanning products, and an intervention promoting these products ... and sunburns among adult women, according to two reports ... , one of the JAMA/Archives journals. Ultraviolet radiation ... category and is the most common avoidable cause of ...
... to any length to try to become part of a ... eating something dicey, or doing illicit drugs, according to a ... "Social exclusion prompts people to use money and ... Mead (Tilburg University), Roy F. Baumeister (Florida State University), Tyler ...
... By Kathleen Doheny HealthDay Reporter , ... studies may help breast cancer patients and their ... after mastectomy. One study finds that about ... having had a mastectomy with immediate reconstruction develop ...
... HealthDay Reporter , MONDAY, Sept. 20 (HealthDay News) -- ... of hearings Monday on whether to recommend approval of ... the advisers recommend approval, it would mark the first ... America,s dinner plates and restaurant menus. Currently, genetically modified ...
... College of Law at Arizona State University has been ... Law Network, which launches today to provide legal and ... challenges such as food safety, health reform and emergency ... Program (PHLPP) received a $1.325 million grant from the ...
Cached Medicine News:Health News:UNC researchers identify genetic patterns that may predict osteoarthritis 2Health News:UNC researchers identify genetic patterns that may predict osteoarthritis 3Health News:Use of sunless tanning products common in teens, may encourage sun safety in women 2Health News:Use of sunless tanning products common in teens, may encourage sun safety in women 3Health News:Money, drugs and chicken feet? What consumers will do for social acceptance 2Health News:Breast Reconstruction After Mastectomy: Now or Later? 2Health News:Breast Reconstruction After Mastectomy: Now or Later? 3Health News:FDA Advisers Weigh Approval of Genetically Modified Salmon 2Health News:FDA Advisers Weigh Approval of Genetically Modified Salmon 3Health News:11-state regional Public Health Law Network office to be established at ASU College of Law 2Health News:11-state regional Public Health Law Network office to be established at ASU College of Law 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: