Navigation Links
Children's Hospital Boston and Pfizer Enter Into Novel Collaborative Research Agreement for Muscular Dystrophy Therapeutics
Date:11/9/2011

BOSTON, Nov. 9, 2011 /PRNewswire-USNewswire/ -- Children's Hospital Boston and Pfizer Inc. (NYSE: PFE) have launched a new collaborative program aimed at identifying potential drug therapies for Duchenne muscular dystrophy (DMD). At the heart of the one-year collaborative research agreement is a novel exchange of expertise that brings the respective strengths of academia and industry together in a framework that could hold promise for benefitting DMD patients in the future.

The agreement focuses on the work of the laboratory of Louis Kunkel, Ph.D., Director of the Program in Genomics at Children's Hospital Boston and discoverer of the dystrophin gene that underlies the biology of DMD. In March 2011, Kunkel and colleagues announced the results of their efforts to screen 1,200 chemicals already approved for human use in a zebrafish model of DMD for any that might have a restorative effect on muscle tissue. Kunkel's team – one of several at Children's engaged in research on rare or orphan diseases – found that several had the desired effect in the zebrafish model, including compounds owned by Pfizer.

Through the agreement, Pfizer will, via its Orphan and Genetic Diseases Research Unit, provide Kunkel access to select proprietary compounds, as well as relevant data about these compounds. Pfizer is also committing internal resources to the project such as medicinal chemistry.

In collaboration with Pfizer's Carl Morris, Ph.D., Kunkel's laboratory will test the compounds provided by Pfizer in the DMD zebrafish model, with an eye toward identifying candidates for further preclinical development.

"This agreement brings together the best of two worlds, namely Pfizer's ability to develop promising new compounds and our ability to test them in physiologically relevant models," Kunkel said. "To have Pfizer show this level of interest in DMD is ve
'/>"/>

SOURCE Children's Hospital Boston
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. The Childrens Hospital of Philadelphia Receives Grand Challenges Explorations Funding
2. Childrens Hospitals and Clinics of Minnesota Opens New Helipad on its Minneapolis Campus
3. UC San Diego Clinical Trials for Latin America International Seminar at Hospital Angeles in Tijuana
4. St. John Hospital 1st in Region to Offer Innovative Chemotherapy Delivery System
5. CareFusion Announces New Ventilation Solution to Help Hospitals Provide Improved Patient Care and Reduce Costs
6. DMC Childrens Hospital of Michigan Selects Allscripts Electronic Health Record for Employed and Affiliated Physicians
7. Novation Commends the White House for Its Support and Advancement of Solutions for American Hospitals Drug Shortage Crisis
8. A Heart for Jordan Merecka: Texas Childrens Hospitals First Total Artificial Heart Patient Receives the Gift of a Donor Heart
9. Mevion Medical Systems Delivers the Worlds First Superconducting Synchrocyclotron for Proton Therapy to Barnes Jewish Hospital
10. Australias Prince of Wales Hospital Launches New Era of Targeted Lung Cancer Treatments with Elektas Advanced 4D Motion Management Technology
11. DMC Harper University Hospital is the First in Michigan to Utilize New Device for Brain Tumor Removal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... Aug. 28, 2015  With the heroin epidemic in ... heights, Jacksonville -based Lakeview Health drug ... is helping to explain why fentanyl is causing a ... to 50 times more potent than pharmaceutical grade heroin ... heroin, the risk of death skyrockets. "Fentanyl ...
(Date:8/28/2015)... According to a new market ... Prostate) Type (Protein & Genetic Biomarkers) Profiling Technology (Proteomics, ... Geography - Global Forecast to 2020", published by MarketsandMarkets, ... 17,689.0 Million USD by 2020 at a CAGR of ... Browse 191 Tables and 38 F ...
(Date:8/28/2015)... DUBLIN , Aug. 28, 2015 ... ) has announced the addition of the ... Capacity and Production" report to their offering. ... Survey of Biopharmaceutical Manufacturing Capacity and Production is ... contract manufacturing organizations, current and projected future capacity ...
Breaking Medicine Technology:Lakeview Health's Dr. Philip Hemphill Explains Why Heroin Addicts Are Now Dying of Fentanyl Overdoses 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 3Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 4Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 512th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 2
... 1, 2011 Advanstar Communications, Inc., a ... the Fashion, Life Sciences and Powersports industries, announced today ... newly created position of Executive Vice President, Pharmaceutical/Science. ... Officer and Chief Administrative Officer roles, this new position ...
... FRANCISCO, March 1, 2011 Practice Fusion, ... community in the US, today announced Jason Portnoy as ... leading, free, cloud-based EMR to physicians; enabling charting, scheduling, ... a period of rapid expansion, bringing his deep expertise ...
Cached Medicine Technology:Veteran Executive Ron Wall Joins Advanstar Communications as Executive Vice President, Pharmaceutical/Science 2Former PayPal, Palantir Executive Jason Portnoy Joins Practice Fusion as CFO 2Former PayPal, Palantir Executive Jason Portnoy Joins Practice Fusion as CFO 3
(Date:8/30/2015)... ... August 30, 2015 , ... Scientists in France say asbestos exposure may ... digestive cancers. Surviving Mesothelioma has just posted an article on the new research. ... measured the cancer incidence among 2,024 French asbestos plant workers from 1978 to 2009. ...
(Date:8/30/2015)... ... August 30, 2015 , ... Nutritional Products International ... assistant to Executive Assistant to CEO Mitch Gould for Nutritional Products International. ... your goals. Kathleen graduated from Florida State University with a Bachelor of ...
(Date:8/29/2015)... ... 29, 2015 , ... On Saturday, September 19, 2015, Diane Blackburn-Zambetti, the Director ... Foundation) will present an educational program titled “Asbestos and Your Health.” , The two ... (doors open at 6:45pm) at Calvary United Methodist Church, 16 E Park Ave., Ambler, ...
(Date:8/29/2015)... ... ... Brands like Toppik , Eau Thermale Avene and Bliss are now available on ... was required to qualify for free standard shipping,” said Jennifer Ramirez, the public relations ... of the item’s selling price.” , With competitive pricing in the e-commerce market for ...
(Date:8/29/2015)... ... 2015 , ... The popular television program VOICES IN AMERICA, hosted by legendary ... be devoting an entire short segment to the subject of diabetes. Diabetes is a ... a daily basis, but recent advancements in medical science may prove to be a ...
Breaking Medicine News(10 mins):Health News:Researchers Say Mesothelioma Not the Only Cancer Linked with Asbestos Exposure, According to Surviving Mesothelioma 2Health News:NPI Appoints New Executive Assistant To CEO 2Health News:Mesothelioma Applied Research Foundation to Hold Educational Class About Asbestos and Mesothelioma Prevention 2Health News:TheBeautyPlace.com Discounts Shipping on Select Brands 2
... will soon have the opportunity to take part in ... the autoimmune disease, ankylosing spondylitis. Approximately 200 patients will ... aims to merge the latest molecular discoveries published by ... medical expertise of physicians and researchers at West China ...
... glaucoma and other conditions , , ... times a day can be difficult for patients to do, and because ... the dose is actually absorbed by the eye. Now, researchers led by ... Delivery at Children,s Hospital Boston, have developed special contact lenses that can ...
... , , , ... Allscripts (Nasdaq: MDRX ), the leader in software, ... Medfusion, the leader in patient-to-provider online communication solutions, today announced ... for Allscripts Electronic Health Record (EHR) and Practice Management clients ...
... 21 /PRNewswire-USNewswire / -- Representatives from leading national ... to honor the 2009 winners of the National Family ... and MetLife Foundation. The event recognized community-based programs supporting ... responsiveness to caregiver needs. , ...
... they,d prefer more flex time and balance in life, , TUESDAY, ... all again, most female surgeons would choose the same career path, ... in the July issue of Archives of Surgery , revealed ... because of their rigorous training and work schedule. , Few female ...
... combined with air pollution, smoking, it raises chances of condition, ... pollution from cars can increase a child,s chances of developing ... get even higher, a new study finds. , For children ... risk, parental stress also increases the risk for asthma, the ...
Cached Medicine News:Health News:Study aims to induce recovery from ankylosing spondylitis 2Health News:A Drug-Dispensing Contact Lens 2Health News:A Drug-Dispensing Contact Lens 3Health News:Allscripts and Medfusion Partner to Provide Patient Portal to Physician Practices Nationwide 2Health News:Allscripts and Medfusion Partner to Provide Patient Portal to Physician Practices Nationwide 3Health News:Allscripts and Medfusion Partner to Provide Patient Portal to Physician Practices Nationwide 4Health News:The National Alliance for Caregiving and MetLife Foundation Honor Innovators Making a Difference in the Lives of Caregivers 2Health News:The National Alliance for Caregiving and MetLife Foundation Honor Innovators Making a Difference in the Lives of Caregivers 3Health News:The National Alliance for Caregiving and MetLife Foundation Honor Innovators Making a Difference in the Lives of Caregivers 4Health News:The National Alliance for Caregiving and MetLife Foundation Honor Innovators Making a Difference in the Lives of Caregivers 5Health News:Female Surgeons Like What They Do, Survey Finds 2Health News:Parental Stress Boosts Kids' Asthma Risk 2Health News:Parental Stress Boosts Kids' Asthma Risk 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: