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Chief Operating Officer Tessie M. Che Departing Company
Date:1/12/2012

SAN DIEGO, Jan. 12, 2012 /PRNewswire/ -- Optimer Pharmaceuticals, Inc. (NASDAQ: OPTR) today announced that Tessie M. Che, Ph.D., Chief Operating Officer & Senior Vice President, Corporate Affairs, is departing the Company to pursue other interests.

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"For the past decade, it's been a great experience building Optimer Pharmaceuticals and bringing DIFICID® to commercialization.  I am quite pleased to see that Optimer continues on a path to achieve the vision we set for the Company back in 1998," commented Tessie M. Che.

"Optimer and DIFICID exist as a result of the perseverance, versatility and operational excellence that Tessie displayed since the creation of our company. Her legacy is inspirational for all of us as we move into the next stage of our development," said Pedro Lichtinger, President and CEO of Optimer. "We wish Tessie well and thank her for her dedication to Optimer and her enduring efforts to bring DIFICID to market."

About Optimer Pharmaceuticals

Optimer Pharmaceuticals, Inc. is a global biopharmaceutical company focused on discovering, developing and commercializing innovative hospital specialty products that have a positive impact on society. Optimer developed and commercialized DIFICID® (fidaxomicin) tablets, an FDA-approved antibacterial drug for the treatment of adult patients with Clostridium difficile-associated diarrhea (CDAD). Optimer has also received marketing authorization for fidaxomicin tablets in the European Union under the trade name DIFICLIR™. The company is seeking marketing authorization for fidaxomicin in Canada and is exploring marketing authorization in other parts of the world where
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