Navigation Links
Ceremed's OSTENE(R) Stops Bone Bleeding Without Added Risk of Surgical Infection, New Study Finds
Date:2/5/2008

LOS ANGELES, Feb. 5 /PRNewswire/ -- New polymer material designed to stop bone bleeding in surgery reduces the risk of surgical infection, according to a new animal study to be published in the February 2008 issue of Clinical Orthopaedics and Related Research (CORR). The study has implications for lowering the risk of hospital-acquired infections, including MRSA.

Researchers from the Medical University of South Carolina at Charleston and Keck School of Medicine at the University of Southern California in Los Angeles compared newly available polymer, Ostene(R), with bone wax, traditionally used to stop bone bleeding in surgically cut bone surfaces. The scientists looked at the two materials' effect on bone infection in the presence of Staphylococcus Aureus, similar to the organism that is responsible for MRSA. The results showed that, when exposed to bacteria, the bones treated with Ostene(R) were four times less likely to get infected than the bones treated with bone wax, 100% of which developed infection. The study also showed that the bones treated with Ostene(R) healed normally, while the presence of bone wax inhibited bone growth.

Bone wax, a beeswax-based product, is the least expensive and most commonly used bone hemostasis material despite its well-documented side effects: Numerous studies indicate that bone wax interferes with the body's ability to clear bacteria and increases the risk of hospital-acquired infections; it is also known to inhibit bone growth and bone healing after surgery.

Ostene(R) offers an alternative that does not increase the risk to patient. Its use in place of bone wax may help reduce serious post-operative complications, including sternal wound infection and the separation of the sternum. The material is used in cardiac, orthopedic, oral, and neurosurgery. Other applications under development include the use of Ostene(R) as a safe, soluble delivery vehicle for a variety of therapeutic agents, from antibiotics to bone growth factors. Ostene(R) is authorized for sale both in the U.S. and the European market.

Ostene(R) is a sterile mixture of water-soluble alkylene oxide copolymers developed as an affordable, easy-to-handle synthetic bone hemostasis material that reduces the overall risk of post surgical infections, sternal non-union, poor bone healing and chronic inflammation. Wax-like and malleable during application, the biomaterial dissolves rapidly and is eliminated from the body shortly after surgery. The material's main polymer component inherently reduces bacterial adhesion. Ostene(R) is the only available product designed to stop bone bleeding in surgery that does not interfere with bone healing or add the risk of surgical infections, including MRSA.

The results of the USC/MUSC study suggest that the use of Ostene(R) may have implications for reducing the risk of surgical site infection and for improving post-operative healing and recovery. The benefits of Ostene(R) may be particularly significant in lowering the rates of serious complications following cardiac surgery, especially among a growing high-risk group of diabetic and overweight patients, who currently represent at least 25% of the 640,000 open heart surgery procedures performed each year in the US.

"Ostene(R)'s unique properties are particularly significant now that we are battling the threat of hospital-acquired infections, especially MRSA," Ceremed's president and CEO Tadeusz Wellisz, M.D., commented on the study. "Ceremed is currently developing the next generation of Ostene(R) with antibiotics, specifically designed to prevent hospital-acquired surgical infection."

About The Company:

Ceremed, Inc. is a privately held medical device corporation formed in 2002 by a surgeon and a group of scientists from the University of Southern California. The company has unique expertise and a portfolio of innovative proprietary technology in the field of soluble alkylene oxide copolymers. These polymers have multiple medical applications, including bone hemostasis and a delivery system for a variety of therapeutic agents.

For additional information about the product or the Company, please contact Danielle Nolan at 310-815-2125 or info@ceremed.com.

For copies of the study please go to: http://www.springerlink.com/content/rk727126p2385460/fulltext.pdf Available Topic Expert(s): For information on the listed expert(s), click appropriate link. Tadeusz Wellisz http://profnet.prnewswire.com/Subscriber/ExpertProfile.aspx?ei=72918


'/>"/>
SOURCE Ceremed, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Cogentus to Launch Phase III Program of Novel Combination Product Designed to Reduce Bleeding Side Effect of Antiplatelet Therapy
2. Study Finds Starion Instruments Tissue Welding Technology Reduces Pain and Bleeding in Tonsillectomy Patients
3. Surgeons Develop Innovative Life-Saving Treatments to Correct Massive Bleeding in Trauma Patients
4. Stem Cell Breakthrough Advances Science Without Ethical Landmines, Says Cardinal
5. Two Major Studies Show: Human Pluripotent Stem Cells without Cloning or Destroying Embryo
6. A Phase II, Randomized, Double Blind, Placebo-Controlled Dose-Escalating Study, Meets the Clinical Endpoints of MTR106 Tablets During the Treatment of Acute Migraine Attacks Without Aura in Females
7. New Topical Therapy Safely Treats Serious Skin Infections Without Systemic Side Effects
8. New Data Suggest Cymbalta(R) Reduced Pain in Fibromyalgia Patients With and Without Depression
9. Zetia Does Not Reduce Carotid Plaque Size When Added to Zocor
10. Ranexa(R) Added to New ACC/AHA Guidelines on Unstable Angina/Non ST-Elevation Myocardial Infarction (UA/NSTEMI)
11. New Non-Surgical Stem-Cell Procedure to Relieve Chronic Tendon Problems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... BRAHMS PCT (procalcitonin) assay as a dedicated testing solution ... this clearance, Roche is the first IVD company in ... sepsis risk assessment and management. PCT is ... levels in blood can aid clinicians in assessing the ...
(Date:6/23/2016)... Bracket , a leading clinical trial technology and specialty ... Bracket eCOA (SM) 6.0, at the 52 nd ... in Philadelphia , Pennsylvania.  A demonstration of ... its kind to fully integrate with RTSM, will be held ... a flexible platform for electronic clinical outcomes assessments that is ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica ... Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs ... Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
Breaking Medicine News(10 mins):