Navigation Links
Ceremed Awarded Third NIH Grant to Develop Soluble Hemostatic Carriers for Targeted Delivery of Therapeutic Agents to the Surgical Site

LOS ANGELES, Oct. 4 /PRNewswire/ -- Ceremed, Inc. was awarded a Small Business Innovation Research (SBIR) grant, the company's third in a series of grants from the National Institutes of Health to develop a versatile soluble carrier with bone hemostatic properties for targeted delivery of therapeutic agents directly to surgical sites. The recently awarded grant will aid Ceremed in its effort to develop a soluble carrier to topically deliver the antibiotic Vancomycin.

Topical delivery of therapeutics is a valuable tool in securing better patient outcomes, particularly in many common cardiac, orthopedic, spinal, and neurosurgical procedures. Ceremed's anhydrous, soluble, and highly malleable carrier is made of proprietary AOC® material. Applied to cut bone, the AOC® carrier will control bleeding and release therapeutic agents as it dissolves without compromising the healing process.

The AOC® formulation with Vancomycin, in combination with a carrier for the antibiotic Gentamicin, under development thanks to an earlier NIH grant, will target both susceptible and methycillin-resistant (MRSA) organisms to help prevent post operative infections, reduce the cost of potentially preventable complications, and improve patient outcomes across surgical fields. The third grant in the series was awarded for the development of an AOC® carrier for DBM. AOC® with DBM allows for stable delivery of bone growth factors directly to the bone, strengthens bone fusion, and promotes significantly earlier onset of healing and postoperative recovery without increased risk of complications.

"Utilizing the AOC® material for delivery of therapeutics has great potential to continue improving patient outcomes across surgical fields," said Ceremed's Chairman Tadeusz Wellisz, MD. "Ceremed has experienced success in developing soluble carriers for DBM and Gentamicin, and we look forward to continued success in the development of AOC® Vancomycin."

About AOC®:

AOC® is Ceremed's proprietary implantable polymer material. It is composed of a blend of Alkylene Oxide Copolymers that are commonly used in the medical field. This unique blend is an ideal carrier because it dissolves without swelling and is eliminated from the body within 48 hours. To dissolve, the material does not require metabolic or inflammatory processes as most resorbable polymers do.  AOC® is synthetic and can be formulated in a range of consistencies with a unique combination of properties, including anhydrous formulations, making it an ideal carrier for compounds that are not stable in aqueous solutions. The material is proving to be a versatile, soluble carrier that delivers a broad range of therapeutics to the surgical site, without compromising the healing process.

AOC® is already used in spinal fusion products, as a soluble coating system for orthopedic and neurosurgical implants, and for bone hemostasis. Ceremed is able to custom-manufacture compounds using any OEM proprietary material in combination with the AOC® biomaterial.

About Ceremed:

Ceremed, Inc. is a privately held medical device corporation founded in Los Angeles, California in 2002.  Ceremed's mission is to utilize its proprietary implantable polymer formulations to enhance the "Standard of Care" by replacing aging and possibly harmful materials with safe and effective materials and devices that bring about better patient outcomes by improving healing and reducing post-surgical complications.  The company manufactures a variety of surgical implantable devices marketed both directly and through partnership licensing and manufacturing arrangements. Ceremed's signature product is the highly successful Ostene® Bone Hemostasis material (

Research leading to the formulation of AOC carriers was supported by NIH Awards # 1R43HL092732, 1R43 HL104840, and 1R41AR056177 from the National Institute Of Arthritis And Musculoskeletal And Skin Diseases and from the National Heart, Lung and Blood Institute. The studies were solely the responsibility of Ceremed, Inc. and do not necessarily represent the official views of the National Institutes of Health.

SOURCE Ceremed, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Ceremeds OSTENE(R) Improves Bone Fusion and Healing After Surgery, New Study Shows
2. Ceremeds OSTENE(R) Stops Bone Bleeding Without Added Risk of Surgical Infection, New Study Finds
3. Twin City Pharmacy & Surgical Awarded NJHPCO 2010 Pharmacists of the Year
4. Generex Awarded a New Patent in Canada for its Proprietary Buccal Drug Delivery System
5. Microfluidic Systems (MFSI) is Awarded Four New Patents in the Field of Automated Biological Sample Processing and Detection.
6. WuXi PharmaTech Awarded GLP Certificate from OECD for Suzhou Toxicology Facility
7. Signum Biosciences Awarded Two Additional NIH Grants for Development of Topical Therapeutics
8. Sysmex America Awarded National Novation GPO Contract for Automated Urinalysis
9. Pfenex Inc. Awarded Contract With the United States Federal Government Potentially Totaling Up to $18.8 Million to Develop a Robust Pfenex Expression Technology Based Process for the Production of Bulk Recombinant Protective Antigen (rPA) From Anthr
10. CRF Health is Awarded for Getting Closer
11. SRI International and Stanford University School of Medicines MISTRAL Collaborative and the Institute for Pediatric Innovation Awarded FDA Grant to Accelerate Commercialization of Pediatric Medical Devices
Post Your Comments:
(Date:11/24/2015)... Connecticut , November 24, 2015 ... of Acadiana has entered into a multi-year agreement ... imaging centers. This investment will provide the Breast Center ... --> Sectra (STO: SECT B) announces that ... agreement to deploy Breast Imaging PACS in its ...
(Date:11/24/2015)... , Nov. 24, 2015  Ascendant Solutions, Inc. (Pink Sheets: ... its Board of Directors has declared a special 1 percent ... dividend is payable December 14, 2015, to shareholders of record ... form of additional shares of common stock. ... Board is a strong endorsement of our confidence in Ascendant,s ...
(Date:11/24/2015)... -- iRhythm Technologies, Inc. , a leading digital health care ... will participate in the 27th Annual Piper Jaffray Healthcare Conference at ... . Kevin King , Chief Executive Officer of ... 8:50am ET. --> --> ... . --> iRhythm is a privately held ...
Breaking Medicine Technology:
(Date:11/24/2015)... ... 2015 , ... Preparing for the LDT Regulation:, CLIA Won’t Satisfy the FDA, ... , FDA has long asserted that design and manufacture of Laboratory Developed Tests (LDTs) ... not meet the device regulations. , Come up short in an inspection and the ...
(Date:11/24/2015)... Richey, FL (PRWEB) , ... November 24, 2015 , ... ... deems a growing epidemic as deaths from prescription opioids in the United States grew ... and cocaine. In 2013 alone, opioids were involved in 37 percent of all fatal ...
(Date:11/24/2015)... ... November 24, 2015 , ... American Family Care (AFC), the ... of a holiday pop-up clinic located in Metro Atlanta’s North Point Mall. The clinic ... and different way. The location is scheduled to operate through Dec. 24. , Holiday ...
(Date:11/24/2015)... CA (PRWEB) , ... November 24, 2015 , ... Cold Shoulder , LLC launched ... Kickstarter last week and hit their goal of $20,000 in under 10 hours. ... aims to bring the new PRO Weight Loss Vest to the market. , The PRO ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... its exceptional customer service: the TrustDale certification. The award recognizes good companies for ... stone honing , tile and grout, and hard surface restoration company earned this ...
Breaking Medicine News(10 mins):