Navigation Links
Ceregene And Alzheimer's Disease Cooperative Study Group Complete Enrollment Of CERE-110 Phase 2 Trial
Date:3/13/2013

SAN DIEGO, March 13, 2013 /PRNewswire/ -- Ceregene, Inc. today announced the completion of enrollment in its double-blind Phase 2 clinical study of CERE-110 (AAV-NGF), a gene therapy product designed to deliver nerve growth factor (NGF) for the treatment of Alzheimer's disease. The clinical study was carried out in collaboration with the Alzheimer's Disease Cooperative Study (ADCS) based at the University of California San Diego (UCSD) and funded by a grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH).  

Forty-nine (49) patients with mild to moderate Alzheimer's disease were treated with CERE-110 at 10 clinical sites throughout the U.S. Approximately half of the patients received CERE-110 while the other half received an appropriate sham (placebo) surgery control treatment. Patients will be followed for a minimum of two years with respect to safety, brain imaging, as well as measures of cognitive function and quality of life. Standard tests used in Alzheimer's clinical trials.

"We are very excited that enrollment in the first blinded study of NGF gene therapy for Alzheimer's disease is now completed and appreciate the courage of all of the patients and their family members that enrolled in this very important study. We also appreciate the efforts of the ADCS and the National Institute on Aging for carrying out and supporting the operational aspects of this study" stated Jeffrey M. Ostrove , Ph.D., president and chief executive officer of Ceregene, Inc., the developer of CERE-110. Dr. Ostrove added "In addition to CERE-110 for Alzheimer's disease, we have also completed enrollment in two controlled Phase 2 clinical trials of CERE-120 for Parkinson's disease. At this time, we would like to recognize the leadership role of Raymond T. Bartus , Ph.D., our chief scientific officer who led the development effor
'/>"/>

SOURCE Ceregene, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Ceregene Parkinsons Disease Study Demonstrates Long-term Neurturin Expression and Enhanced Dopamine Activity 4 Years Following Delivery of CERE-120 (AAV2-neurturin)
2. Abattis Participates In Project On A Whole Plant Therapeutic For Treating Malaria And Other Diseases And Reducing Drug Resistance
3. Takeda Submits Marketing Authorisation Application for Vedolizumab in Moderately to Severely Active Ulcerative Colitis and Crohns Disease in the European Union
4. Alzheimers Drug Discovery Foundation Awards Grant To CohBar to Develop A Novel Peptide Therapeutic For Alzheimers Disease
5. Acquired Orphan Blood Diseases Therapeutics Market to 2019 - Search for Disease Modifying Drugs Central to Unlocking Premium Pricing Potential
6. Parkinsons Disease: World Drug Market 2013-2023
7. NeuroDerm Announces Positive Results of a Phase I Study of ND0612 for the Treatment of Parkinsons Disease
8. Adventrx To Develop ANX-188 For Complications Of Arterial Disease
9. Aethlon Medical (AEMD) Note: Multiple Shots on Goal - A Therapeutic Strategy to Address Infectious Disease & Cancer
10. Independent Study Published in Clinical Infectious Diseases Highlights the Importance of Antimicrobial Removal Systems in Blood Culture to Rapidly and Accurately Aid in the Diagnosis of Sepsis
11. Shire Supports Rare Disease Day 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... ALBANY, N.Y. , March 5, 2015  AMRI ... Michael Pettersson , fills the newly created position of ... Christopher Conway , Senior Vice President of Global ... Mr. Pettersson will lead the international sales team in ... market share in targeted market segments. Mr. Pettersson will ...
(Date:3/5/2015)... - Cross reference: Picture is ... - Hitachi Medical Systems Europe è ... OASIS* all,ECR 2015. Si tratta di un sistema ... T che migliora la capacità diagnostica dei sistemi già ... del paziente. Le nuove funzionalità di OASIS permettono una ...
(Date:3/5/2015)... PRINCETON, N.J. , March 5, 2015 ... late stage biopharmaceutical company committed to developing products that ... oncology and biodefense, announced today that its President and ... will give a corporate presentation at the 27 th ... California , on Tuesday, March 10, 2015 at ...
Breaking Medicine Technology:AMRI Hires VP of International Sales 2Hitachi Medical Systems Europe lancia la nuova generazione di OASIS*: Il sistema di RM aperta ad alto campo da 1.2 T. Ancora più valore al paziente 2Hitachi Medical Systems Europe lancia la nuova generazione di OASIS*: Il sistema di RM aperta ad alto campo da 1.2 T. Ancora più valore al paziente 3Hitachi Medical Systems Europe lancia la nuova generazione di OASIS*: Il sistema di RM aperta ad alto campo da 1.2 T. Ancora più valore al paziente 4Soligenix to Present at the 27th Annual ROTH Conference 2Soligenix to Present at the 27th Annual ROTH Conference 3
... median survival vs. ... parallel external controls -, IRVINE, Calif., Nov. 2 ... from the Phase 2 study of,its investigational agent IDM-2101 which showed ... responses,and showed a positive survival trend in patients with non-small cell ...
... In a move to improve,significantly the safety ... emergency medical information service, has joined,the Alzheimer,s Association ... offer MedicAlert(R) + Safe Return(R). Currently, there are ... almost 10 million,people caring for someone with Alzheimer,s ...
Cached Medicine Technology:IDM Pharma Announces IDM-2101 Updated Phase 2 Results Show Treatment Well Tolerated With Positive Survival Trend in Lung Cancer Patients 2IDM Pharma Announces IDM-2101 Updated Phase 2 Results Show Treatment Well Tolerated With Positive Survival Trend in Lung Cancer Patients 3IDM Pharma Announces IDM-2101 Updated Phase 2 Results Show Treatment Well Tolerated With Positive Survival Trend in Lung Cancer Patients 4MedicAlert Foundation Joins The Alzheimer's Association to Offer MedicAlert(R) + Alzheimer's Association Safe Return(R) - Live 24-Hour Emergency Response for Wandering and Medical Emergencies 2MedicAlert Foundation Joins The Alzheimer's Association to Offer MedicAlert(R) + Alzheimer's Association Safe Return(R) - Live 24-Hour Emergency Response for Wandering and Medical Emergencies 3
(Date:3/5/2015)... The global digital PCR (dPCR) and qPCR market is expected to ... to 2019. , The global digital PCR (dPCR) and qPCR market ... to 2019. Although the mature markets such as the U.S., Germany, ... and qPCR market the Asia-Pacific region is expected to grow at ... of the digital PCR (dPCR) and qPCR market is driven by ...
(Date:3/5/2015)... 05, 2015 This week, ... in low-cost laminate flooring products, initiating widespread concern ... eco-friendly building materials made primarily from bamboo, stands ... all their flooring products for volatile organic compounds ... Benchmark International (BMH). Results from formaldehyde emissions ...
(Date:3/5/2015)... 2015 AxoGen, Inc. (NASDAQ: AXGN) ... peripheral nerve repair market, reported record revenue of $4.79 ... compared to $2.98 million in the year-ago fourth quarter ... , “Our strong fourth quarter revenue growth reflects ... products which is driving increased surgeon adoption of our ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 Testosterone lawsuits ... allegedly suffered heart attacks, strokes and other serious cardiovascular ... therapies continue to move forward in the federal multidistrict ... of Illinois. According to a Case Management Order issued ... for the use of master pleadings in the proceeding. ...
(Date:3/5/2015)... Rhode Island Medical Imaging (RIMI) was pleased ... to support the Providence College (PC) women’s basketball program’s fight ... of the ‘Think Pink’ uniforms, which were worn during the ... DePaul University at Alumni Hall/Mullaney Gymnasium in Providence, R.I. ... the PC women’s basketball’s ‘Pink Out’ event,” said Dr. Scott ...
Breaking Medicine News(10 mins):Health News:New Research Report by MarketsandMarkets on Digital PCR and qPCR Market Worth $3.97 Billion by 2019 2Health News:New Research Report by MarketsandMarkets on Digital PCR and qPCR Market Worth $3.97 Billion by 2019 3Health News:New Research Report by MarketsandMarkets on Digital PCR and qPCR Market Worth $3.97 Billion by 2019 4Health News:With Homeowners Concerned About Formaldehyde, Cali Bamboo Puts Safety Above Bottom Line 2Health News:AxoGen, Inc. Reports 61% Revenue Growth for the 2014 Fourth Quarter 2Health News:AxoGen, Inc. Reports 61% Revenue Growth for the 2014 Fourth Quarter 3Health News:AxoGen, Inc. Reports 61% Revenue Growth for the 2014 Fourth Quarter 4Health News:Testosterone Lawsuits Move Forward, as Bernstein Liebhard LLP Comments on Most Recent Order Issued in Federal Litigation 2Health News:Testosterone Lawsuits Move Forward, as Bernstein Liebhard LLP Comments on Most Recent Order Issued in Federal Litigation 3Health News:Testosterone Lawsuits Move Forward, as Bernstein Liebhard LLP Comments on Most Recent Order Issued in Federal Litigation 4Health News:RIMI Teams Up with PC Women’s Basketball in the Fight Against Breast Cancer 2
... Boston University researchers has found that the majority of ... health. They also found that opioid users, in particular, ... of one year. These findings appear online in the ... health, dental medicine and internal medicine faculty from Boston ...
... HealthDay Reporter , THURSDAY, April 14 (HealthDay ... breast cancer survivors after successful treatment stems from a ... of the autonomic nervous system, with the former working ... a new study suggests. Researchers from Ohio State ...
... reveals that there is no association between a restaurant worker,s ... able to provide a safe meal to a food allergic customer. ... as 8% of children in the UK alone. Allergic reactions can ... which can cause death. Led by Professor Helen Smith of Brighton ...
... With mounting evidence that patient-centered care improves ... Indiana University School of Medicine are providing a ... physicians to master relationship skills as well as ... Century medicine. "Crossing the Patient-Centered ...
... from the National Institute of Standards and Technology ... Huntington,s disease, an inherited degenerative brain disorder that ... progressively leads to physical impairment, dementia and death. ... disease has a 50-50 chance of getting the ...
... This release is available in French and ... research group composed of professors Antonio Campos and Miguel Alaminos ... la Cruz Cardona (opticians) and the ophthalmologist Miguel Gonzlez Andrades, ... organ in Spain Researchers extracted pig corneal cells and ...
Cached Medicine News:Health News:Nervous System Imbalance May Cause Fatigue in Breast Cancer Survivors 2Health News:Nervous System Imbalance May Cause Fatigue in Breast Cancer Survivors 3Health News:Training future doctors to enlist patients as partners in care 2Health News:New NIST SRM helps improve diagnosis of Huntington's disease 2
Inquire...
Inquire...
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
Medicine Products: