Navigation Links
Ceregene And Alzheimer's Disease Cooperative Study Group Complete Enrollment Of CERE-110 Phase 2 Trial
Date:3/13/2013

SAN DIEGO, March 13, 2013 /PRNewswire/ -- Ceregene, Inc. today announced the completion of enrollment in its double-blind Phase 2 clinical study of CERE-110 (AAV-NGF), a gene therapy product designed to deliver nerve growth factor (NGF) for the treatment of Alzheimer's disease. The clinical study was carried out in collaboration with the Alzheimer's Disease Cooperative Study (ADCS) based at the University of California San Diego (UCSD) and funded by a grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH).  

Forty-nine (49) patients with mild to moderate Alzheimer's disease were treated with CERE-110 at 10 clinical sites throughout the U.S. Approximately half of the patients received CERE-110 while the other half received an appropriate sham (placebo) surgery control treatment. Patients will be followed for a minimum of two years with respect to safety, brain imaging, as well as measures of cognitive function and quality of life. Standard tests used in Alzheimer's clinical trials.

"We are very excited that enrollment in the first blinded study of NGF gene therapy for Alzheimer's disease is now completed and appreciate the courage of all of the patients and their family members that enrolled in this very important study. We also appreciate the efforts of the ADCS and the National Institute on Aging for carrying out and supporting the operational aspects of this study" stated Jeffrey M. Ostrove , Ph.D., president and chief executive officer of Ceregene, Inc., the developer of CERE-110. Dr. Ostrove added "In addition to CERE-110 for Alzheimer's disease, we have also completed enrollment in two controlled Phase 2 clinical trials of CERE-120 for Parkinson's disease. At this time, we would like to recognize the leadership role of Raymond T. Bartus , Ph.D., our chief scientific officer who led the development effor
'/>"/>

SOURCE Ceregene, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Ceregene Parkinsons Disease Study Demonstrates Long-term Neurturin Expression and Enhanced Dopamine Activity 4 Years Following Delivery of CERE-120 (AAV2-neurturin)
2. Abattis Participates In Project On A Whole Plant Therapeutic For Treating Malaria And Other Diseases And Reducing Drug Resistance
3. Takeda Submits Marketing Authorisation Application for Vedolizumab in Moderately to Severely Active Ulcerative Colitis and Crohns Disease in the European Union
4. Alzheimers Drug Discovery Foundation Awards Grant To CohBar to Develop A Novel Peptide Therapeutic For Alzheimers Disease
5. Acquired Orphan Blood Diseases Therapeutics Market to 2019 - Search for Disease Modifying Drugs Central to Unlocking Premium Pricing Potential
6. Parkinsons Disease: World Drug Market 2013-2023
7. NeuroDerm Announces Positive Results of a Phase I Study of ND0612 for the Treatment of Parkinsons Disease
8. Adventrx To Develop ANX-188 For Complications Of Arterial Disease
9. Aethlon Medical (AEMD) Note: Multiple Shots on Goal - A Therapeutic Strategy to Address Infectious Disease & Cancer
10. Independent Study Published in Clinical Infectious Diseases Highlights the Importance of Antimicrobial Removal Systems in Blood Culture to Rapidly and Accurately Aid in the Diagnosis of Sepsis
11. Shire Supports Rare Disease Day 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... YORK , Nov. 24, 2014  AiCure, ... and motion-sensing technology to monitor medication ingestion, has ... to monitor and intervene with patients receiving medication ... Fatal overdoses from prescription opiates have quadrupled ... more deaths per year than heroin, cocaine and ...
(Date:11/24/2014)... , Nov. 24, 2014  Rigel Pharmaceuticals, Inc. (Nasdaq: ... is retiring from the board of directors and from ... Raul Rodriguez , most recently serving as the company,s president ... executive officer and join the board of directors.  Gary ... 2005, will become chairman. Mr. Gower is expected to remain ...
(Date:11/24/2014)... PLYMOUTH MEETING, Pa. , Nov. 24, 2014  Inovio ... Dr. J. Joseph Kim , President and CEO of ... board and management team to ring the Nasdaq Opening Bell ... celebration of Inovio,s September 15 th listing on the ... bell ringing ceremony, Dr. Kim said, "We are honored to ...
Breaking Medicine Technology:Can artificial intelligence solve the $55 billion problem of opioid abuse? 2Rigel Announces Executive Management Changes 2Rigel Announces Executive Management Changes 3Inovio Pharmaceuticals to Ring Opening Bell Nov 25th on the Nasdaq Stock Market 2Inovio Pharmaceuticals to Ring Opening Bell Nov 25th on the Nasdaq Stock Market 3
... Taylor Strategy Partners (TSP), who enable clients in the life science ... organizations, is pleased to announce the expansion of its operations to ... is headquartered in Columbus, OH with additional offices in New York, ... Director, will be taking the lead of the Kansas City office. ...
... Friday, June 10, 2011 at twelve o,clock noon, NMT ... Joseph F. Finn, Jr., C.P.A. ("Finn") of the firm ... the benefit of NMT Medical creditors. ... that designed, developed, manufactured and marketed proprietary implant technologies ...
Cached Medicine Technology:Taylor Strategy Partners Set to Open Office in Kansas City in June 2011 2NMT Medical, Inc. Sealed Bid Sale of its Intellectual Property to Take Place Friday, June 10, 2011 at Twelve O'Clock Noon 2
(Date:11/24/2014)... Francisco, California (PRWEB) November 24, 2014 ... reach USD 6.19 billion by 2020, according to ... Increasing incidence rates of cardiac arrhythmias clubbed with ... drivers of this market. Though still in the ... a significant rise in usage rates in the ...
(Date:11/24/2014)... 2014 Volpara Solutions announced today ... the 100th Annual Meeting of the Radiology Society ... (RSNA Booth 1752 – South Hall). Volpara Solutions ... the rest of its innovative suite of quantitative ... enable personalized measurements of volumetric density, patient-specific dose, ...
(Date:11/24/2014)... November 24, 2014 Residents of retirement ... in this year’s SENIORS GOT TALENT, an annual online ... From piano players to classic crooners, to seniors partying ... older adults are indeed living young. , “SENIORS GOT ... there’s a cash prize, has always been about highlighting ...
(Date:11/24/2014)... Olaparib functions as a chemical of ... one of the first PARP inhibitors. Sufferers with BRCA1/2 ... of melanoma, and are often immune to other types ... malignancies a exclusive weaknesses, as the tissues of melanoma ... and allow them to proceed splitting. This implies that ...
(Date:11/24/2014)... The Holiday Inn Westbury - Long Island ... Association to donate various items consisting of practical, ... such items.The Association's program is aimed toward helping over ... nursing homes, assisted living facilities and nursing homes. The ... of seniors throughout the Long Island area. The Holiday ...
Breaking Medicine News(10 mins):Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 3Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 4Health News:Volpara Solutions to Launch VolparaAnalytics 1.2 at RSNA 2Health News:Volpara Solutions to Launch VolparaAnalytics 1.2 at RSNA 3Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 2Health News:Nursing Homes & Assisted Living Retirement Communities Enter Seniors Guide's Seniors Got Talent 3Health News:Olaparib Industry (CAS 763113-22-0) 2009-2019 Global and China Research Reports is Now Available at RnRMarketResearch.com 2Health News:Olaparib Industry (CAS 763113-22-0) 2009-2019 Global and China Research Reports is Now Available at RnRMarketResearch.com 3Health News:Olaparib Industry (CAS 763113-22-0) 2009-2019 Global and China Research Reports is Now Available at RnRMarketResearch.com 4Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 2Health News:The Holiday Inn Westbury - Long Island gives back to the local Long Island community, and also goes beyond borders to assist those in need during the 2014 Holiday Season 3
... available in Spanish . Researchers headed ... New York and by Mara Macas at the Institute for ... by which some proteins that are essential for life, called ... fruit of three years of intense work, the study reports ...
... Institute (JASRI) have successfully produced a first beam of ... This light was created using SACLA, a cutting-edge X-ray ... February 2011 in Harima, Japan. SACLA (SPring-8 Angstrom Compact ... of atoms and molecules at a level of detail ...
... By Alan Mozes HealthDay Reporter , THURSDAY, June ... exercise habits of America,s teens, new data from the U.S. ... picture. Not only are high school kids guzzling far ... the CDC research team found. In fact, just one ...
... steady reduction in overall cancer death rates translates to ... 1990 and 2007, according to the latest statistics from ... 2011, and its companion consumer publication Cancer Facts & ... segments of the population equally. A special section of ...
... A team of social scientists and medical and nursing ... has pinpointed how a programme, which ran in more ... reduced the rates of potentially deadly central line bloodstream ... patient safety programmes. Funded in part by the ...
... Child Development (e-publication ahead of print) finds ... lead to a mathematical learning disability and difficulty in ... just one cause of math learning disabilities, according to ... Kennedy Krieger Institute. Approximately 6 to 14 percent ...
Cached Medicine News:Health News:Discovery of a new mechanism of gene control that is associated with cancer 2Health News:First X-ray lasing of SACLA 2Health News:High School Kids Get Too Many Sugary Drinks, Too Little Exercise: CDC 2Health News:High School Kids Get Too Many Sugary Drinks, Too Little Exercise: CDC 3Health News:American Cancer Society report finds continued progress in reducing cancer mortality 2Health News:American Cancer Society report finds continued progress in reducing cancer mortality 3Health News:American Cancer Society report finds continued progress in reducing cancer mortality 4Health News:International team works out secrets of one of world's most successful patient safety programs 2Health News:International team works out secrets of one of world's most successful patient safety programs 3Health News:Poor 'gut sense' of numbers contributes to persistent math difficulties 2Health News:Poor 'gut sense' of numbers contributes to persistent math difficulties 3
... a cast from an arm or leg can ... cut or burned by the cast saw blade. ... remove any cast with confidence. This innovative, cut-resistant ... burns from the cast saw and can be ...
... bypass grafting or creation of a vascular ... tunnel is of the utmost importance in ... answer for those seeking a high-precision tunneling ... the risk of twisting or kinking for ...
... In pediatric cardiac surgery, modified Blalock-Taussig ... prior to total correction. GORE-TEX Vascular Grafts ... of surgeons worldwide for use as shunts ... offer such benefits as ease of implantation ...
... have met the challenges of the most ... Recognized for exceptional performance and quality, they ... worldwide. These grafts require no preclotting, resist ... assure utmost thrombectomy safety. The Gore vascular ...
Medicine Products: