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Cepheid Receives Grant to Develop Ten-Color Real-Time PCR Detection Technology for Use in the GeneXpert(R) System
Date:6/10/2009

ology, gives us the ability to detect as many as 100 distinct targets in a single test. This feature eliminates the need for guesswork, and when performed on the GeneXpert System, will help deliver cost-effective, medically actionable results to clinicians and their patients."

Building upon the success of Cepheid's six-color Xpert(R) MTB/RIF test, clinical utility of the ten-color system will be demonstrated through development of a new assay for multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis (MTB). Future GeneXpert-based tests, which apply the ten-color technology, are expected to follow.

"Our goal is to continue the transformation of the clinical mycobacteriology laboratory by making it possible to replace time-intensive and less sensitive culture processes with rapid, sensitive, and accurate molecular techniques that that are not constrained to a central laboratory environment," said UMDNJ's David Alland, M.D. "This dramatic increase in the number of targets we can detect with a single test will enable us to develop an assay for MDR and XDR Mycobacterium tuberculosis that will give clinicians a full panel of information, including resistance to the widest variety of treatments."

About the GeneXpert(R) System Molecular Diagnostic Platform

The GeneXpert System is a closed, self-contained, fully-integrated and automated platform that represents a paradigm shift in the automation of molecular analysis, producing accurate results in a timely manner with minimal risk of contamination. The GeneXpert System is the only system to combine on-board sample preparation with real-time PCR (polymerase chain reaction) amplification and detection functions for fully integrated and automated nucleic acid analysis. The system is designed to purify, concentrate, detect, and identify targeted nucleic acid sequences thereby delivering answers directly from unproce
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