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Centocor Ortho Biotech Inc. Announces NDA Submission for Abiraterone Acetate for the Treatment of Metastatic Advanced Prostate Cancer
Date:12/20/2010

" said William N. Hait, M.D., Ph.D., Global Therapeutic Head, Oncology, Johnson & Johnson Pharmaceutical Research & Development, LLC.  "We believe that we can develop important therapies to treat devastating diseases by focusing on the tumor microenvironment.  Abiraterone acetate is a key part of this strategy, and we look forward to working with health authorities to provide a new therapeutic option for metastatic advanced prostate cancer patients."

If approved, abiraterone acetate will be commercialized and distributed by Centocor Ortho Biotech Inc. in the U.S. and by Janssen Pharmaceutical Companies in all other countries around the world.

About Metastatic Advanced Prostate Cancer

Prostate cancer is considered to be advanced when metastases beyond the prostate occur and when resistance emerges to conventional hormonal therapies.  Metastatic advanced prostate cancer is also referred to as castration-resistant prostate cancer, or CRPC, when disease progresses despite conventional hormone therapies or appearance of new metastases.

Prostate cancer occurs when cancer cells form in the tissues of the prostate.  The prostate is a gland located around the urethra (under the bladder) in men that produces part of the seminal fluid.  In some cases, cancer of the prostate can grow slowly compared with other cancers.  However, depending on factors including characteristics specific to the patient and the tumor, prostate cancer can also grow very quickly and spread widely.

Prostate cancer is the second most common type of cancer in American men.  One in six men will be diagnosed with prostate cancer, and in the United States in 2009, nearly 200,000 men were diagnosed with the disease. In 2010, an estimated 217,000 new cases of prostate cancer and 32,000 related deaths are expected to be reported in the United States.

About Centocor Ortho Biotech Inc.

Centocor Ortho Biotec
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SOURCE Centocor Ortho Biotech Inc.
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