Navigation Links
Cempra Announces Comparable Efficacy of Oral Solithromycin (CEM-101) Compared with Levofloxacin in Phase II Clinical Trial in Patients with Community-Acquired Bacterial Pneumonia (CABP)
Date:9/15/2011

1 to 5).  Patients were enrolled if diagnosed with PORT II-to-IV pneumonia.  The primary outcome measure was continued improvement or complete resolution of baseline signs and symptoms in the intent to treat (ITT) and the clinically evaluable (CE) populations at the Test of Cure (TOC) visit, which was completed five to 10 days after the last dose of the drug.

"Cempra's mission is to develop differentiated antibiotics that confront today's challenges of bacterial resistance to existing antibiotics," said Prabhavathi Fernandes, president and chief executive officer of Cempra.  "Completing this Phase II trial is an important milestone for the company. I congratulate our staff for their good work.  The data from this study strongly support further evaluation of orally-administered CEM-101 in the treatment of CABP in an 'all-oral therapy' Phase III trial, and as a component of IV-to-oral Phase III trials."

About CEM-101

CEM-101 is the first fluoroketolide with a number of attributes that may provide clinically important advantages over several comparator products.  Our clinical trials and pre-clinical studies have shown that CEM-101, with its unique chemical structure, has:

  • a favorable safety and tolerability profile;
  • comparable efficacy to the current standard of care;
  • potent activity against a broad range of bacteria with excellent tissue distribution and intracellular activity;
  • a lower incidence of resistance development;
  • IV, oral and suspension formulations that allow it to be used in all patient populations and settings; and
  • anti-inflammatory qualities to help patients feel better sooner during treatment.

The annual incidence for CABP in the United States is over five million with over one million hospitalized (File, T.M., Lancet, 2003; File, T.M. and Tan, J.S. JAMA, 2005; CDC, National Hospital Dis
'/>"/>

SOURCE Cempra Pharmaceuticals
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Cempra Pharmaceuticals to Present at the 2011 Wells Fargo Healthcare Conference
2. Cempra Pharmaceuticals to Present at the Jefferies 2011 Global Healthcare Conference
3. Cempra Pharmaceuticals to Present at Two Investor Conferences in Paris
4. Intravenous (IV) Administration of Cempra Pharmaceuticals Solithromycin (CEM-101) Demonstrates Excellent Systemic Tolerability in a Phase 1 Clinical Trial
5. Cempra Pharmaceuticals to Present at Two Upcoming Cambridge Healthtech Institute (CHI) Conferences
6. Cempra Pharmaceuticals to Present at Two Upcoming Investor Conferences
7. Cempra Expands Clinical Management Team to Advance Leading Antibacterial Clinical Programs Solithromycin and TAKSTA™
8. Cempra Pharmaceuticals Names Carl Foster Executive Vice President of Business Development
9. Cempra Pharmaceuticals Names Richard Kent, M.D., to Its Board of Directors
10. Cempra Pharmaceuticals to Present at the UBS Global Life Sciences Conference
11. Cempra Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... Calif. , Nov. 26, 2014  Avanir ... that the U.S. Food and Drug Administration (FDA) ... New Drug Application (NDA) for AVP-825. AVP-825 is ... sumatriptan powder delivered intranasally utilizing a novel Breath ... Complete Response letter, and consistent with the preliminary ...
(Date:11/26/2014)... 2014  BioScrip ® , Inc. (NASDAQ: BIOS ) ... Executive Officer, will present at the Bank of America Merrill Lynch ... , Date: , , , Wednesday, December 3, 2014 , ... , , , Location: , , , Boca Raton Resort ... Inc. BioScrip, Inc. is a leading national ...
(Date:11/26/2014)... JOSE, Calif. , Nov. 26, 2014 /PRNewswire/ ... technologies to produce novel therapies for infectious diseases, ... , M.D., an internationally recognized key opinion leader ... the Company,s scientific advisory board. Founder ... Ph.D., stated, "We believe Dr. Opal,s extensive experience ...
Breaking Medicine Technology:Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 2Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 4Aridis Pharmaceuticals Appoints Dr. Steven Opal to Scientific Advisory Board 2Aridis Pharmaceuticals Appoints Dr. Steven Opal to Scientific Advisory Board 3
... MALVERN, Pa., Nov. 17, 2010 Siemens ... System is now commercially available in the United ... diagnostic mammography, stereotactic biopsy, and upgrade capability to ... (Logo: http://photos.prnewswire.com/prnh/20070904/SIEMENSLOGO ) ...
... The National Community Pharmacists Association (NCPA) ... to unite to host what the organizers are calling ... the eastern Suffolk area of New York. ... ) According to event organizer and NCPA ...
Cached Medicine Technology:Siemens MAMMOMAT Inspiration Digital Mammography Commercially Available in U.S. 2Siemens MAMMOMAT Inspiration Digital Mammography Commercially Available in U.S. 3NCPA Commends Prescription Drug Take Back Event Hosted by 15 New York Pharmacies 2NCPA Commends Prescription Drug Take Back Event Hosted by 15 New York Pharmacies 3
(Date:11/28/2014)... November 28, 2014 Earlier in ... during the hugely popular, 2014 MTV Video Music ... Truth launched ground-breaking celebrity centered television advertisements directed ... viewership figures were estimated by Entertainment Weekly ... placed the spotlight on celebrities photographed by paparazzi ...
(Date:11/28/2014)... UniWigs.com, a leader in the wig industry, has announced ... next Monday. This promotion features: , > 400 ... to 70% off (no coupon code needed), > ... on orders over $49 , Visit http://www.uniwigs.com for more ... 28th to Dec. 1st and the first 100 shoppers each day ...
(Date:11/28/2014)... An inventor from Flint, Mich., wants to minimize ... this idea while lying in a hospital bed, unable to ... The Bed Buddy provides a more ergonomic and convenient way ... eliminates the need to leave the bed, which avoids hassle ... to use and producible in design variations, it's ideal for ...
(Date:11/28/2014)... talklocal ( http://www.talklocal.com ) is ... service professionals by phone in about 90 seconds. , ... tornadoes were reported to have touched down just north of ... following the tornadoes, Denver residents now know all too well ... is like having local pros in over 50 service categories ...
(Date:11/28/2014)... Texas (PRWEB) November 28, 2014 ... worldwide dental market along with the definite portrayal ... point by point depiction of various variables driving ... patterns and difficulties blocking the development of the ... http://www.marketreportsonline.com/376605.html . , According to the report ...
Breaking Medicine News(10 mins):Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 2Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 3Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 4Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 5Health News:Pre-X'mas Crazy Sale Starts from $0 at UniWigs.com 2Health News:TalkLocal Launches In Denver A Week After Multiple Tornadoes Hit Near City 2Health News:Global Dental Market Report 2014 Edition Now Available at MarketReportsOnline.com 2Health News:Global Dental Market Report 2014 Edition Now Available at MarketReportsOnline.com 3
... a night of sleep is equivalent of the amount of energy ... Alternatively, looked at in terms of food, a night of ... about the amount found in two slices of bread or a ... energy saved during sleep may seem small, it was actually more ...
... News) -- Adults who were children when their parents divorced ... grew up in intact families, according to a new study. ... 695 who were younger than 18 when their parents divorced. ... Men whose parents divorced when they were children were ...
... , This release is available in Spanish ... of Granada warns about the negative effects of the ... and attitudes of men towards women, which are based on ... themselves for women. The research revealed that when individuals ...
... , AUGUSTA, Ga. Fat appears to associate with some ... may help explain why obesity can increase the risk for ... , The finding, published in BMC Medicine , may ... according to Dr. Xiaoling Wang, genetic epidemiologist at the Medical ...
... published in The American Journal on Addictions ... has become common among young American male weightlifters. Additionally, ... with polysubstance abuse involving both performance-enhancing and classical drugs. ... by elite athletes, has become cheaply available for illicit ...
... State University sleep researchers have determined that the air ... commuter flight was substantially fatigued when he failed ... runway and cleared it for takeoff. , Writing in ... researchers come short of saying his fatigue caused the ...
Cached Medicine News:Health News:Study Finds Lack of Sleep Leads to Lost Calories 2Health News:Parents' Divorce May Contribute to Suicidal Thoughts Years Later 2Health News:Warning about 'benevolent sexism' and men's apparently positive attitudes towards women 2Health News:Fat associated with chemical changes in DNA that may help explain obesity-related disease 2Health News:WSU researchers apply fatigue model to fatal commuter air crash 2
Used for stenting the urethra after hypospadias or epispadias repair and to provide post-operative drainage of the bladder. Supplied sterile in peel-open packages. Intended for one-time use....
... for temporary internal drainage ... to the bladder. Supplied ... Intended for one-time use. ... advised; C-Flex® and Sof-Flex® ...
Used to introduce Cook-Cope loop and other catheters for percutaneous nephrostomy. Supplied sterile in peel-open packages. Intended for one-time use....
Used to establish a percutaneous tract into the renal pelvis for catheter placement or stone manipulation. Supplied sterile in peel-open packages. Intended for one-time use....
Medicine Products: