Navigation Links
Cempra Announces Comparable Efficacy of Oral Solithromycin (CEM-101) Compared with Levofloxacin in Phase II Clinical Trial in Patients with Community-Acquired Bacterial Pneumonia (CABP)
Date:9/15/2011

1 to 5).  Patients were enrolled if diagnosed with PORT II-to-IV pneumonia.  The primary outcome measure was continued improvement or complete resolution of baseline signs and symptoms in the intent to treat (ITT) and the clinically evaluable (CE) populations at the Test of Cure (TOC) visit, which was completed five to 10 days after the last dose of the drug.

"Cempra's mission is to develop differentiated antibiotics that confront today's challenges of bacterial resistance to existing antibiotics," said Prabhavathi Fernandes, president and chief executive officer of Cempra.  "Completing this Phase II trial is an important milestone for the company. I congratulate our staff for their good work.  The data from this study strongly support further evaluation of orally-administered CEM-101 in the treatment of CABP in an 'all-oral therapy' Phase III trial, and as a component of IV-to-oral Phase III trials."

About CEM-101

CEM-101 is the first fluoroketolide with a number of attributes that may provide clinically important advantages over several comparator products.  Our clinical trials and pre-clinical studies have shown that CEM-101, with its unique chemical structure, has:

  • a favorable safety and tolerability profile;
  • comparable efficacy to the current standard of care;
  • potent activity against a broad range of bacteria with excellent tissue distribution and intracellular activity;
  • a lower incidence of resistance development;
  • IV, oral and suspension formulations that allow it to be used in all patient populations and settings; and
  • anti-inflammatory qualities to help patients feel better sooner during treatment.

The annual incidence for CABP in the United States is over five million with over one million hospitalized (File, T.M., Lancet, 2003; File, T.M. and Tan, J.S. JAMA, 2005; CDC, National Hospital Dis
'/>"/>

SOURCE Cempra Pharmaceuticals
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Cempra Pharmaceuticals to Present at the 2011 Wells Fargo Healthcare Conference
2. Cempra Pharmaceuticals to Present at the Jefferies 2011 Global Healthcare Conference
3. Cempra Pharmaceuticals to Present at Two Investor Conferences in Paris
4. Intravenous (IV) Administration of Cempra Pharmaceuticals Solithromycin (CEM-101) Demonstrates Excellent Systemic Tolerability in a Phase 1 Clinical Trial
5. Cempra Pharmaceuticals to Present at Two Upcoming Cambridge Healthtech Institute (CHI) Conferences
6. Cempra Pharmaceuticals to Present at Two Upcoming Investor Conferences
7. Cempra Expands Clinical Management Team to Advance Leading Antibacterial Clinical Programs Solithromycin and TAKSTA™
8. Cempra Pharmaceuticals Names Carl Foster Executive Vice President of Business Development
9. Cempra Pharmaceuticals Names Richard Kent, M.D., to Its Board of Directors
10. Cempra Pharmaceuticals to Present at the UBS Global Life Sciences Conference
11. Cempra Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2015)... Ga. , April 23, 2015 WellStar ... care available to its patients with the most advanced ... in Georgia to offer TomoTherapy ... United States to offer both TomoTherapy and ... TomoTherapy System rotates 360 degrees around the patient, which ...
(Date:4/23/2015)... , April 23, 2015  Hill-Rom Holdings, Inc., (NYSE: ... management presentation at the Deutsche Bank 40 th ... 9:20 a.m. EDT. You are invited to ... at http://ir.hill-rom.com/events.cfm or access it directly at ... will be available one hour after conclusion of the ...
(Date:4/23/2015)... 2015  To commemorate the upcoming 25 th anniversary of ... long-anticipated ADA Legacy Tour will make a stop at ... at the New Jersey Convention & Expo Center in ... will be Friday and Saturday 11 am to 5 pm, and ... Tour is a traveling exhibit designed to raise public awareness and ...
Breaking Medicine Technology:WellStar's New, Highly Targeted Therapy Shortens Cancer Treatment Time 2ADA 25th Anniversary Legacy Tour Stops at Abilities Expo New York Metro, May 1-3 2ADA 25th Anniversary Legacy Tour Stops at Abilities Expo New York Metro, May 1-3 3
... , WILMINGTON, Del., Dec. 8 ... enrolled in the company,s Medicare Part D prescription savings program ... program. , (Logo: http://www.newscom.com/cgi-bin/prnh/20091027/PH99766LOGO ) , ... physician,s offices under the changes to the AZ&Me(TM) Prescription Savings ...
... , WALTHAM, ... leading research and advisory firms for pharmaceutical and healthcare issues, ... levofloxacin, moxifloxacin and piperacillin/tazobactam -- will be the primary factors ... the community-acquired pneumonia drug market though 2018. , The new ...
Cached Medicine Technology:AstraZeneca Medicare Part D Patient Assistance Program No Longer Requires Co-Pays 2Patent Expiries of Blockbuster Antibiotics Will Fuel a Decline of More Than 15 Percent in the Community-Acquired Pneumonia Drug Market 2
(Date:4/24/2015)... 24, 2015 The Fastest Fat Loss Week ... great success of the Xtreme Fat Loss Diet, has been ... fat loss blueprint that claims to help one lose belly ... HealthyandFitZone.com's Stan Stevenson, prompting an investigative review. , "Our ... creators spent years researching and experimenting with these methods on ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Lowcostcarinsuranceprice.com has ... low cost auto insurance for senior citizens . ... drivers, but this does not mean that they cannot ... even senior drivers can find the right coverage for ... insurance brokerage website like http://lowcostcarinsuranceprice.com/ provides free ...
(Date:4/24/2015)... 2015 “Kind,” “selfless,” “the voice of ... ways Denise Weiner described pediatric oncology nurse Laura Vasquez ... daughter, Alexa, during her five-year battle with a malignant ... marrow transplant and numerous experimental treatments, Vasquez continued caring ... when she was not in the hospital and even ...
(Date:4/24/2015)... “ Opera ” was featured on NewsWatch as ... and coolest technology products available to consumers. Andrew Tropeano, a ... and shared with viewers how this is the fastest way ... internet would not be in existence. But each web browser ... is no different. Celebrating their 20th anniversary this year, Opera ...
(Date:4/24/2015)... Pastor and Overseer at The House of Yahweh, has written ... worldwide, and how they would not be necessary if the ... nations have been trained to build up armed defense forces ... and distrust. , “The nations believe they must use ... rules and laws, and the rape of their sons, daughters, ...
Breaking Medicine News(10 mins):Health News:Fastest Fat Loss Week Ever Review Revealed on Healthy & Fit Zone 2Health News:Low Cost Auto Insurance Quotes for Senior Citizens 2Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 2Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 3Health News:CURE™ Magazine Names Pediatric Nurse Laura Vasquez from Children’s Hospital Los Angeles As Extraordinary Healer™ of 2015 4Health News:A Web Browser That Connects over 350 Million People was Featured on NewsWatch Television 2Health News:Armed Forces Would Not Be Necessary if Biblical Laws Were Followed, Says Yisrayl Hawkins in New Article 2
... and education complex in Islamabad to cater to the health ... the twin city of Rawalpindi . ,The complex ... a Health and Education City in the capital, and includes ... dentistry. ,Harvard Medical International (HMI) is a ...
... and a standardized rehabilitation protocol are successful in returning ... today at the 2007 Annual Meeting of the American ... Center. ,Dr. Brunt and colleagues studied the ... to evaluate the experience of athletes undergoing tension-free mesh ...
... of the American Orthopaedic Society for Sports Medicine at ... in the arm bone and soft tissue of the ... help protect them against injury. ,Young baseball ... as they mature, says principal investigator Scott D. Mair, ...
... of sex, a move that is proving highly controversial among ... workers more vulnerable . ,Men who buy sex ... fine or face both, under proposed legislation currently under consultation ... the buying of sex, but not the sale. Procuring, or ...
... what Victoria Beckham is really wishing for, is a baby girl ... that she and hubby David Beckham will try to add to ... hoping theyll be bringing back a bundle of pink from the ... little girl, is because after all those boys in the house, ...
... Institute for Learning and Memory have uncovered a molecular ... traumatic events . ,The work could lead ... adults who suffer each year from persistent, debilitating fears ... Iraq and Afghanistan. ,A study conducted by the ...
Cached Medicine News:Health News:Surgical Repair of Athletic Hernia Speeds Return to Play 2Health News:Surgical Repair of Athletic Hernia Speeds Return to Play 3Health News:Shoulder Protection by Throwing Motion in Baseball Players 2Health News:Prostitutes Fume as Norway Bids to Criminalise Sex Purchases 2Health News:Prostitutes Fume as Norway Bids to Criminalise Sex Purchases 3Health News:First Drug for Post-traumatic Stress Disorder 2
... New Sorvall Discovery 90SE ... need to discover more. ... come with top-of-the-line performance, ... ease of use, all ...
... centrifuge continues to raise the standard for ... 1,048,000 x g performance and our new ... sample sizes from 0.2 ml to 8.3 ... direct drive, very quiet operation, rotor imbalance ...
... versatility, and environmental safety are ... LE-80 K Ultracentrifuge from Beckman ... Optima centrifugation technology, the LE-80 ... effectively provide advanced capability for ...
... Capable of generating 694,000 ... to 90,000 rpm, Beckman Coulter's ... to perform more separations in ... model operates with a broad ...
Medicine Products: