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Cellular Biomedicine Group Announces Positive Interim Results from Phase I/IIa Clinical Trial for Treatment of Knee Osteoarthritis (KOA)
Date:9/6/2013

nts were screened, and 18 of them were eligible for the inclusion criteria and enrolled in the trial with their informed consent. To date, half of the subjects have completed a total of 2 doses of intra-articular injections and the scheduled 6 follow-up observations, and no serious adverse events (SAEs) have been reported.

The trial is conducted by Shanghai's Renji Hospital, a tertiary hospital affiliated to Shanghai Jiao Tong University School of Medicine.

"Our adipose-derived MPC therapy for KOA utilizes our proprietary medical device, the A-Stromal™ Kit," commented Li (Helen) Zhang, BM, Vice President of Technology and Manufacturing at CBMG. "With this patented kit, approved as a medical device by China's SFDA, we use the patient's own haMPC, which negates the need for immunosuppression or donor matching. In addition, our proprietary technology allows us to produce a high yield of adipose-derived vascular stromal cells (haVSC) from only 30-50mL of adipose tissue, thus minimizing pain and recovery time following the lipoaspiration procedure. This is very significant for China, where patients typically do not have a lot of body fat. The haVSCs are further differentiated and expanded to haMPCs with our proprietary cell culture technology."

About the Therapy
Cellular Biomedicine Group's therapy for KOA is an interventional therapy that consists of 30-50mL of adipose tissue obtained via lipoaspiration from the patient, from which the patient's haMPCs are then expanded using CBMG's proprietary technology. After three weeks there is an initial injection into the knee joints and a second injection three weeks later.

About Cellular Biomedicine Group
Cellular Biomedicine Group, Inc. develops proprietary cell therapies for the treatment of certain degenerative diseases and cancers.  Our developmental stem cell
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SOURCE Cellular Biomedicine Group
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