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Cellular Biomedicine Group Announces Enrollment Milestone for Phase I Clinical Trial for Liver Cancer
Date:5/22/2013

PALO ALTO, Calif., May 22, 2013 /PRNewswire/ -- Cellular Biomedicine Group (OTCQB: CBMG) today announced that it has achieved half of the enrollment of the total projected enrollment required for its Phase I trial to evaluate the safety and preliminary efficacy of TC-DC (Tumor Stem Cell Specific Dendritic Cell) therapy for hepatocellular carcinoma (HCC), the most common type of liver cancer. To date the trial has had no Severe Adverse Effect (SAE) reported.

The Phase I clinical trial for TC-DC therapy for HCC, registered with NIH under number NCT01828762 (click here to view) is an open label clinical trial conducted with Shanghai's PLA 85 Hospital, one of the Liver Disease Centers of People's Liberation Army. The trial will evaluate the safety and efficacy in lowering the incidence of tumor recurrence and metastasis by means of autologous immune cell therapy in primary HCC patients following standard tumor resection and TACE chemotherapy.

Cellular Biomedicine Group's VP and GM of the Autologous Products Business Unit, Cheng Xiang (Chase) Dai, MD, commented, "We expect that enrollment will progress quickly and this study is on schedule to complete Phase I clinical trials."

Hepatocellular Carcinoma
Forty-five percent of the world's HCC patients are in China, with over 300,000 new patients diagnosed every year. Currently the therapies commonly offered to most patients are surgery and local chemotherapy, with a 2-year recurrence rate of 51% and median survival time of 13 months.

The TC-DC therapy that CBMG is developing has had extraordinary US phase II metastatic melanoma trial results, with a 5 year overall survival of 54% in the TC-DC group versus 10% in the control group, and a median survival time of 4.5 years for the TC-DC group, versus 1.3 years for the control group with standard therapies.'/>"/>

SOURCE Cellular Biomedicine Group
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