Celldex Therapeutics Receives Fast-Track Designation for CDX-110, a Novel EGFRvIII Vaccine for Gl...(ns as are appropriate to expedite the de...),Health

About Celldex Therapeutics, Inc.

Celldex Therapeutics, Inc. is a biotechnology company focused on developing therapeutic vaccines that target and stimulate the body's immune system for the treatment of cancer, infectious and autoimmune diseases. Celldex has three product candidates already in or about to enter clinical development targeting multiple cancers and Hepatitis B. Four additional product candidates are in preclinical development for cancer and autoimmune disease. Celldex's proprietary technology platform uses fully human monoclonal antibodies administered directly to patients to target and stimulate dendritic cells - key cells within the immune system. The Company is headquartered in Phillipsburg, New Jersey. On October 22, 2007, Celldex and AVANT Immunotherapeutics, Inc. announced that they had signed a definitive merger agreement. The all-stock transaction, approved by both companies' Boards of Directors, will combine Celldex and AVANT. Closing of the merger is contingent upon a vote of approval by the current stockholders of AVANT at a special meeting expected to take place in the first quarter 2008. For more information, please visit the website: http://www.celldextherapeutics.com.

Additional Information about the Merger and Where to Find It This communication contains "forward-looking" statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements are typically preceded by words such as "believes," "expects," "anticipates," "intends," "will," "may," "should," or similar expressions. These forward- looking statements are subject to risks and uncertainties that may cause actual f
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