Navigation Links
Celladon Announces Presentation of Clinical Data From First-in-Human MYDICAR(R) Trial for Advanced Heart Failure at American Heart Association Scientific Sessions
Date:11/9/2008

inical studies of more than 500 patients. AAV vectors are the product of decades of research focused on the safety of gene transfer agents, and are derived from components of a non-replicating, non-pathogenic, commonly occurring human virus. AAV vectors do not integrate into the chromosome and are considered non-mutagenic. In addition, they have not been associated with the types of inflammatory reactions observed in trials involving adenoviral vectors, which are known to induce acute inflammation of tissues due to activation of the body's immune system.

About Heart Failure

Heart failure is the leading medical cause of hospitalization and is expected to result in estimated direct and indirect costs to the healthcare system in 2008 of $35 billion. Despite important therapeutic advances in pharmacologic and device therapies, the prognosis of heart failure patients remains poor. Access to nonpharmacologic therapies, such as heart transplantation and the use of mechanical assist devices, is restricted to a fraction of patients who need them. About 5 million people in the United States have heart failure, and another 550,000 new cases are diagnosed each year. Heart failure contributes to or causes about 280,000 deaths annually. The most common symptoms of heart failure are shortness of breath, feeling tired, and swelling in the ankles, feet, legs, and sometimes the abdomen. There is no cure for heart failure.

About Celladon

Celladon was launched in October 2004 as a privately held biotechnology company founded with the goal of becoming the leader in developing molecular therapies for the treatment of heart failure. The company's products target the key enzyme deficiency in advanced heart failure, SERCA2a, which regulates calcium cycling and contractility in heart muscle cells. Celladon's first generation product candidate, MYDICAR, delivers the gene for the SERCA2a enzyme. MYDICAR is currently being tested in Phase 1 and 2 clinical trials. Cel
'/>"/>

SOURCE Celladon Corporation
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Portola Announces Data Presentations Relevant to Its Lead Phase II Antithrombotic Compounds at American Heart Association Scientific Sessions 2008
2. Poniard Pharmaceuticals Announces Final Top-Line Results from Phase 1 Trial Demonstrating Positive Bioavailability with Oral Picoplatin
3. VIA Pharmaceuticals Announces Conference Call and Webcast to Discuss VIA-2291 Phase 2 Data Presentations at AHA
4. NicOx Announces Favorable Blood Pressure Data for Naproxcinod in a Large ABPM Study
5. Michael J. Fox Foundation Announces $11 Million in 2009 Funding for Translational, Pre-Clinical and Clinical Parkinsons Disease Research
6. CEL-SCI Announces Expansion of Exclusive Licensing Agreement for Cancer Drug Multikine
7. Mpex Pharmaceuticals Announces Initiation of a Phase 2 Clinical Trial of Aerosol MP-376 in COPD
8. CuraGen Announces Preliminary Data from Ongoing Phase II Study Showing Clinical Activity of CR011-vcMMAE in Patients with Metastatic Melanoma
9. Cell Therapeutics Announces Study Data Set Cut-off for Phase III Pivotal Pixantrone (301) Trial
10. Anadys Pharmaceuticals Announces Single Dose Safety and Pharmacokinetics Results for ANA598 in Healthy Volunteers
11. Lutonix Inc. Announces $20 Million Series B Financing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... , May 21, 2013   Regulus Therapeutics ... leading the discovery and development of innovative medicines targeting ... , Ph.D., Chief Operating Officer and Executive Vice ... Deutsche Bank 38th Annual Healthcare Conference on Wednesday, May ... being held at the Westin Boston Waterfront Hotel. ...
(Date:5/21/2013)... May 21, 2013  LCA-Vision Inc. (NASDAQ: LCAV ... the Lasik Plus ® brand, announces that all nominees to ... at today,s annual meeting of stockholders.  These Directors are: ... President of Bahl & Gaynor Investment Counsel , ... , Edgar F. Heizer III , ...
(Date:5/21/2013)... -- Zacks.com announces the list of stocks featured in the ... discuss the latest news and events impacting stocks and ... include Actavis, Inc.,s (NYSE: ACT ), BP plc ... ), Petrobras (NYSE: PBR ) and Devon Energy ... http://photos.prnewswire.com/prnh/20101027/ZIRLOGO ) Get the most recent ...
Breaking Medicine Technology:Regulus to Present at Deutsche Bank 38th Annual Healthcare Conference 2LCA-Vision Reports on Annual Meeting of Stockholders 2LCA-Vision Reports on Annual Meeting of Stockholders 3LCA-Vision Reports on Annual Meeting of Stockholders 4The Zacks Analyst Blog Highlights: Actavis, BP, Total, Petrobras and Devon Energy 2The Zacks Analyst Blog Highlights: Actavis, BP, Total, Petrobras and Devon Energy 3The Zacks Analyst Blog Highlights: Actavis, BP, Total, Petrobras and Devon Energy 4The Zacks Analyst Blog Highlights: Actavis, BP, Total, Petrobras and Devon Energy 5
(Date:5/21/2013)... of the adenoids and tonsils, is performed 500,000 times ... treatment for children with obstructive sleep apnea. However, ... executive functioning, behavior, sleep apnea symptoms, and quality of ... A study led by Susan Redline, MD, MPH, ... and Associate Clinic Director of the Division of Sleep ...
(Date:5/21/2013)... 21, 2013 The Las Vegas personal injury ... announce that Crawford Gates, a senior at Coronado High School, ... scholarship essay contest . As the winner of the essay ... contest started on Dec. 1, 2012 and ran through April ... submit a three-page minimum essay on “The Role of the ...
(Date:5/21/2013)... Harbor, Florida (PRWEB) May 21, 2013 ... agency, announced today that they have redesigned their website ... a nude beach, pool, hot tubs, bars and dining. ... this nudist resort including sales and guest reviews, will ... island of Jamaica itself, including pages on culinary local ...
(Date:5/21/2013)... A new study appearing in the current ... cells harvested from fat (adipose) are more potent than ... the body’s immune system. , The finding could ... adipose tissue-derived stem cells (AT-SCs) are far more plentiful ... and can be collected from waste material from liposuction ...
(Date:5/21/2013)... 21, 2013 The American Diabetes Association ... in the United States of America are affected with ... a great risk of developing peripheral neuropathy which unfortunately ... The ADA further goes on saying that the disease ... around 2 million new cases are diagnosed every year ...
Breaking Medicine News(10 mins):Health News:Early removal of adenoids and tonsils can help pediatric sleep apnea symptoms 2Health News:Benson, Bertoldo, Baker & Carter is Pleased to Announce the Winner of its First Annual College Scholarship Essay Contest 2Health News:The Oldest and Original Nudist Travel Agency for NResort Announced Today a Redesigned Website Featuring Information on Culinary Events, Flora and Fauna, and Photography 2Health News:Stem Cells from Fat Outperform Those from Bone Marrow in Fighting Disease 2Health News:Stem Cells from Fat Outperform Those from Bone Marrow in Fighting Disease 3Health News:Neuracel Aims to Reduce Peripheral Neuropathy Pain 2
... Texas to Receive this Honor, AUSTIN, Texas, May ... announced today that the hospital network was,selected as one ... the highest honor bestowed by the State of Texas ... by the Quality Texas Foundation, is based on St.,David,s ...
... Major Part of Unprecedented ,Justice for,All, Plan to Change ... million, mobilize tens of,thousands during and AFTER the election ... May 8 Members and leaders of the,nation,s strongest ... strictly accountable if they say one thing before an ...
... GHX electronic trading exchange enables fully ... May 8 GHX Mobile Solutions today,announced that ... SalesAccelerator,handheld inventory management tool that can now read ... capability, healthcare manufacturers can,more broadly utilize SalesAccelerator to ...
... Who says the best,times of your life have already ... (http://www.HealthCentral.com ) has recently,brought on The Midlife Gals, two ... the responsibility of caring for their elderly mother,comes the ... face of others., Known for their personal blog, ...
... Webcast and Archived Replay Instructions Below, SAN ... MXWL ) will conduct its Annual Meeting of ... Spectrum Center Drive., For those who are ... live,via the following link:, http://www.maxwell.com/investors/investor-calendar.asp . The webcast ...
... SAN DIEGO (May 8, 2008) The La Jolla ... $7.1 million grant from the National Institutes of Health ... antibody treatment that quickly fights the smallpox virus. ... defense in protecting against a terrorist-originated smallpox outbreak and ...
Cached Medicine News:Health News:St. David's HealthCare Granted the State's Top Honor for Quality and Performance Excellence 2Health News:St. David's HealthCare Granted the State's Top Honor for Quality and Performance Excellence 3Health News:SEIU Members to Politicians: Live Up to Your Promises or We Will Hold You Accountable 2Health News:SEIU Members to Politicians: Live Up to Your Promises or We Will Hold You Accountable 3Health News:SEIU Members to Politicians: Live Up to Your Promises or We Will Hold You Accountable 4Health News:GHX Mobile Solutions' SalesAccelerator Tool Adds Capability to Read RFID Tags, as Well as Barcodes 2Health News:The HealthCentral Network Signs Spunky 'Midlife Gals' for Comedic Relief on Alzheimer's, Skin Care Sites 2Health News:NIH awards LIAI major grant to test safety of new smallpox treatment 2Health News:NIH awards LIAI major grant to test safety of new smallpox treatment 3
... performing of plugs and allow precise control of ... and sorting. Colored graduations are enameled onto the ... calibrated "To Deliver" its total capacity when the ... L 8 350 mm Measur range: ...
... opening allows more rapid intake and delivery of ... onto the glass. Two narrow bands or one ... is calibrated"To Deliver"its total capacity when the last ... 350 mm graduations and accuracy 0-4.9 0.1 ...
Corning 7078 Calibrated"to deliver". multi-pack plugged capacity 5 mL...
... These disposable 0.5mL PYREX glass ... (TD) with blow-out and offer ... make pipetting go faster and ... graduations and fire polished tips ...
Medicine Products: