Navigation Links
Cell Therapeutics to Re-submit Pixantrone NDA in Consideration for Accelerated Approval in Accordance with Guidance from FDA's Office of New Drugs
Date:5/2/2011

th particular specificity for CpG rich, hyper-methylated sites. These structural differences resulted in significantly enhanced anti-lymphoma activity compared to doxorubicin in preclinical models. In addition, the structural motifs on anthracycline-like agents that are responsible for the generation of oxygen free radicals and the formation of toxic drug-metal complexes have also been modified in pixantrone in an effort to prevent the binding of iron and perpetuation of superoxide production--both of which are the putative mechanism for anthracycline induced acute cardiotoxicity. These novel pharmacologic differences may allow re-introduction of anthracycline-like potency in the treatment of relapsed/refractory diffuse large lymphoma without unacceptable rates of cardiotoxicity.

About Cell Therapeutics, Inc.

Headquartered in Seattle, CTI is a biopharmaceutical company committed to developing an integrated portfolio of oncology products aimed at making cancer more treatable. For additional information, please visit www.CellTherapeutics.com http://www.CellTherapeutics.com.

Sign up for email alerts and get RSS feeds at our Web site, http://www.CellTherapeutics.com/investors_alert

This press release includes forward-looking statements that involve a number of risks and uncertainties the outcome of which could materially and/or adversely affect actual future results and the market price of CTI's securities. Specifically, the risks and uncertainties that could affect the development of pixantrone include risks associated with preclinical and clinical developments in the biopharmaceutical industry in general, and with pixantrone in particular, including, without limitation, the potential failure of pixantrone to prove safe and effective for the treatment of relapsed or refractory di
'/>"/>

SOURCE Cell Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Grifols and Talecris Biotherapeutics Announce the Signing of a Consent Agreement With FTC Staff
2. Pearl Therapeutics to Present Complete PT003 Results from Phase 2b COPD Study in a Late-Breaker Session at the American Thoracic Society Annual Meeting
3. Halozyme Therapeutics to Host First Quarter 2011 Financial Results Conference Call on May 6
4. United Therapeutics Corporation Reports First Quarter 2011 Financial Results
5. Cell Therapeutics, Inc. Announces Institutional Investors Purchase Approximately $16.0 Million of Preferred Stock and Warrants
6. Prime Therapeutics President and CEO Eric Elliott Delivers Speech at University of Minnesota College of Pharmacy Dialogues in Managed Care Leadership 2011
7. Cell Therapeutics, Inc. Reports First Quarter Accomplishments and Financial Results
8. JumpStart Ventures Invests in Cleveland-based SPR Therapeutics
9. New Biopharmaceutical Company to Accelerate Delivery of Vaccines and Protein Therapeutics
10. Vista Partners Updates Coverage on Opexa Therapeutics, Inc.; Maintains Target Price of $6.50
11. Mersana Therapeutics Appoints Michael A. Metzger as EVP & COO
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... , June 2, 2015 Today ... joins over 150 major food companies, retailers, and ... House Forum on Antibiotic Stewardship. CSTE is committed ... antibiotic-resistant bacteria, detect resistant strains, preserve the efficacy ... of resistant infections. CSTE continues to ...
(Date:6/2/2015)... , June 2, 2015  ErgoNurse, the leader in bedside ... healthcare products in the United States , ... home, long-term care and skilled nursing markets. ... Thousands ... to fully take advantage of the ErgoNurse products to stop ...
(Date:6/2/2015)... CAMBRIDGE, Mass. , June 2, 2015 /PRNewswire/ ... has expanded its offerings with the addition of ... ARISg™, a world leader in safety data collection ... safety and regulatory affairs professionals, and expert physicians, ... industry, provide clinical interpretation and monitoring of safety ...
Breaking Medicine Technology:ErgoNurse and Briggs Healthcare Positioned to Completely Eliminate the Unnecessary Cost of Healthcare-Related Back Injuries 2PROMETRIKA Announces the Availability of Pharmacovigilance Services 2
(Date:6/2/2015)... 2015 Highly qualified dental care specialists inside ... drive prolific change in the dental tourism industry in Europe. ... Clinic offers a full range of superior dental services ... dental tourism. , Partnered with a top medical tourism ... advancing dentistry and has earned a reputation as an influential ...
(Date:6/2/2015)... Orlando, FL (PRWEB) June 02, 2015 ... can enjoy quality care in a more convenient location ... Publix in Partin Village Plaza, 2310 E. Irlo Bronson ... location is located less than a mile away from ... with warm décor, more spacious patient areas with digital ...
(Date:6/2/2015)... June 02, 2015 The Down Syndrome ... Potter from the hit show Glee as the keynote ... Walk in Pleasant Prairie, WI. The event aims to ... in Racine, Kenosha, and Walworth counties. ... join us for this important event," says Dawn Nuoffer, ...
(Date:6/2/2015)... 2015 The 3TVPhoenix contest, conducted in partnership ... station’s 6:00 a.m. Good Morning Arizona program for a code ... Facebook page. , Lisa Allen of Scottsdale was ... plans to apply the monthly $1,000 prize to her mortgage ... mom, expressed her surprise and gratitude at winning, indicating that ...
(Date:6/2/2015)... Los Angeles (PRWEB) June 02, 2015 ... a letter of intent to partner and expand urgent ... is subject to approval by the University of California ... The planned transaction will allow UCLA Health to purchase ... centers in Beverly Hills, Calabasas, Newbury Park and Northridge ...
Breaking Medicine News(10 mins):Health News:Team Dental Clinic Unveils Plan to Drive Change in the Dental Tourism Industry 2Health News:Team Dental Clinic Unveils Plan to Drive Change in the Dental Tourism Industry 3Health News:Coast Dental Office Opening In Kissimmee with Expanded Technology 2Health News:Glee star Lauren Potter helps Down Syndrome Association of WI raise awareness, support 2Health News:Scottsdale Resident Named $12,000 Prize Winner- Arizona Central and KTVK 3TV Phoenix Partner in Mortgage Giveaway Contest 2Health News:UCLA Health Partners With Exer - More Than Urgent Care 2
... Service Employees International Union taking immediate legal ... by California Nurses,Association, WASHINGTON, April 17 ... announced plans to file a motion to,dismiss ... the California,Nurses Association against SEIU President Andy ...
... of America,(PHA) today strongly denounced efforts by opponents ... farm bill in their continuing effort,to close all ... the latest effort by opponents of hospitals that ... and non-physician,corporations and has already drawn strong criticism ...
... the cancer may have an Achilles, heel, report suggests , , ... has forced metastatic melanoma into remission for the first time, ... The case involves a 79-year-old woman with melanoma tumors in ... abnormality in a gene called KIT, so the patient was ...
... MONICA, Calif., April 17 Consumer,Watchdog today praised ... insurance coverage of patients left uninsured, uninsurable,and often ... when their,health insurance policies were illegally cancelled after ... that reinstatements must be,complete and retroactive, with no ...
... 17 The American,Chemistry Council (ACC) today sent ... FDA to update its review of the safety ... extensive body of scientific study regarding bisphenol A ... reports have,raised concerns about the safety and use ...
... money for crucial research, advocacy and ... ... announced its first-ever national fundraising and awareness,campaign -- the Hemophilia Walk, presented ... partner with local,chapters in five cities across the U.S. to raise much ...
Cached Medicine News:Health News:SEIU to File Motion to Dismiss CNA Restraining Order 2Health News:Physician Hospitals of America Denounces 'Farm Bill' Plan to Sell Out Seniors and Physicians to Pay for Agribusiness Subsidies 2Health News:Gleevec Pushes Advanced Melanoma Into Remission 2Health News:Consumer Watchdog Praises CA HMO Regulator's Promise to Reinstate Health Coverage for Wrongfully Cancelled Patients; Cautions That All Health Costs During Gap Must be Covered 2Health News:ACC Calls on FDA to Update Review of Bisphenol A 2Health News:ACC Calls on FDA to Update Review of Bisphenol A 3Health News:National Hemophilia Foundation Asks America to Make a Difference With National Fundraising Initiative 2
Helical Stone Basket...
Nitinol Tipless Stone Basket...
A breakaway microwell EIA for the detection of toxins produced by Enterohemorrhagic E. coli...
For presumptive identification of E. coli serogroup O157:H7 cultured on laboratory media....
Medicine Products: