Navigation Links
Cell Therapeutics Announces Study Data Set Cut-off for Phase III Pivotal Pixantrone (301) Trial
Date:11/2/2008

Novartis notified of data set closing, Top-line results expected in

November

SEATTLE, Nov. 3 /PRNewswire-FirstCall/ -- Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) announced today that it has closed the data set for preliminary analysis of the primary endpoint in the phase III EXTEND (PIX301) trial of pixantrone (BBR2278) for patients with relapsed diffuse large B cell non-Hodgkin's lymphoma (NHL) and it has provided Novartis notice that the data set has been closed. The primary endpoint for the study is the complete remission (CR) and unconfirmed complete remission (uCR) rate in patients receiving either pixantrone or another single agent chemotherapeutic drug. CTI plans to report top-line results in November.

"We are excited to have reached the end of the treatment phase and follow-up period for the pixantrone pivotal study and look forward to reporting top-line results in November," said James A. Bianco, M.D., CEO of Cell Therapeutics. "Complete remissions in this patient population with end stage advanced disease are seldom accomplished with the current standard of care. Pixantrone, if successful in achieving the study objectives, could offer these patients a significant benefit, and we would work with the FDA to submit an NDA in 2009."

CTI has an existing license and co-development agreement with Novartis for OPAXIO(TM) (paclitaxel poliglumex, CT-2103), which also provides Novartis with an option to enter into an exclusive worldwide license to develop and commercialize pixantrone based upon agreed terms.

About the EXTEND (PIX301) Clinical Trial

The EXTEND clinical trial is a phase III single agent trial of pixantrone for patients with relapsed, aggressive non-Hodgkin's lymphoma who received two or more prior therapies and who were sensitive to treatment with anthracyclines. The trial was conducted at 130 sites in 17 countries. Patients were randomized to receive either pixantr
'/>"/>

SOURCE Cell Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. InteRNA Technologies and VU University Medical Center to Develop microRNA-Based Diagnostics and Therapeutics for Cancer
2. Sirion Therapeutics Announces Positive Pivotal Uveitis Data for Durezol(TM)
3. XTENT Announces Clinical Trial Data to be Presented at Annual Meeting of Transcatheter Cardiovascular Therapeutics Next Week
4. Alba Therapeutics Presents New Data for Larazotide Acetate at the 2008 American College of Gastroenterology Annual Scientific Meeting
5. In Vivo Data on Taligen Therapeutics Pipeline Candidates Presented at the XXII International Complement Workshop
6. BN ImmunoTherapeutics Announces Positive Mature Phase II Results From Newly Acquired Prostate Cancer Vaccine
7. Video: Sirion Therapeutics Launches Durezol for Postoperative Ocular Inflammation and Pain
8. Orexigen(R) Therapeutics Presents Data on Its Proprietary Formulation of Naltrexone Sustained Release (SR) Used in Contrave(R)
9. PTC Therapeutics Announces Data Showing Six-Minute Walk Test Consistently Measures Ambulatory Function in Patients With Duchenne Muscular Dystrophy
10. Data from In Vivo Disease Models on Taligen Therapeutics Pipeline Candidates to be Presented at the XXII International Complement Workshop
11. Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... 2, 2015  Konica Minolta, Inc. (Konica Minolta) ( ... has acquired Sawae Technologica Ltda., an X-ray system equipment ... , through its Brazilian healthcare sales company, Konica Minolta ... Local Brazil market investment and ... exceeding 200 million, significant healthcare technical advancements and efficiencies ...
(Date:7/2/2015)...  The Commission for Certification in Geriatric Pharmacy ... that represents pharmacists in acute and ambulatory settings, ... for recertification of Certified Geriatric Pharmacists.  ASHP will ... this purpose.  ASHP will join the American Society ... CCGP Professional Development Program. ...
(Date:7/2/2015)... 2015   BioLife Solutions , Inc. (NASDAQ: BLFS ... grade cell and tissue hypothermic storage and ... biologistics cold chain management app for smart shippers ... Business Magazine has included BioLife in its annual list ... Washington state for 2015. Now ...
Breaking Medicine Technology:Konica Minolta Acquires Sawae, Enhancing Digital X-ray Diagnostic Imaging Systems in Brazil 2Konica Minolta Acquires Sawae, Enhancing Digital X-ray Diagnostic Imaging Systems in Brazil 3Commission for Certification in Geriatric Pharmacy Adds ASHP as Professional Development Program Provider 2BioLife Solutions Named One of the 100 Best Companies to Work For in Washington State 2BioLife Solutions Named One of the 100 Best Companies to Work For in Washington State 3
... Sept. 28 Reportlinker.com announces that a ... its catalogue: Diagnostic Imaging ... India, and China) 2010 – 2015". ... Report DescriptionThe market for diagnostic imaging ...
... 28 Reportlinker.com announces that a new market ... Global Pico Projector By Application, ... http://www.reportlinker.com/p0304770/Global-Pico-Projector-By-Application-Technology--Products-Market-2010-2014.html ... to revolutionize the global projector market by making ...
Cached Medicine Technology:Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 2Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 3Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 4Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 5Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 6Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 7Reportlinker Adds Diagnostic Imaging Equipment - Emerging Markets (BRIC- Brazil, Russia, India, and China) 2010 - 2015". 8Reportlinker Adds Global Pico Projector By Application, Technology & Products Market (2010-2014) 2Reportlinker Adds Global Pico Projector By Application, Technology & Products Market (2010-2014) 3Reportlinker Adds Global Pico Projector By Application, Technology & Products Market (2010-2014) 4Reportlinker Adds Global Pico Projector By Application, Technology & Products Market (2010-2014) 5Reportlinker Adds Global Pico Projector By Application, Technology & Products Market (2010-2014) 6
(Date:7/2/2015)... VA (PRWEB) , ... July 02, 2015 , ... ... Congresswoman Donna Edwards (D-Md.) for her introduction of the Stop Overdose Stat (S.O.S.) ... introduced by Senator Jack Reed (D-R.I.), this Act seeks to decrease drug overdose ...
(Date:7/2/2015)... ... ... With summer in full swing, Americans are flocking to Canada’s many lakes to reel in ... in the world, and it’s easy to understand why. From the Pacific Northwest Coast of ... Recreational fishing is a huge industry, and Americans make up the vast majority of anglers ...
(Date:7/2/2015)... ... July 02, 2015 , ... As Americans celebrate the Fourth of July outdoors ... is on the rise. July is UV Safety Month, and physicians at American Family ... of getting skin checks. Experts say most skin cancers can be found early with ...
(Date:7/2/2015)... ... July 02, 2015 , ... Six months ahead of his 80th birthday, ... raise awareness and money for the Pulmonary Hypertension Association (PHA). Stevenson began the ... near Washington, D.C. by mid-September. He left Glasgow, Mont. yesterday morning and is making ...
(Date:7/2/2015)... PLAINSBORO, N.J. (PRWEB) , ... July 02, 2015 ... ... ACO and Emerging Healthcare Delivery Coalition met for the late June Web-based ... moves forward with new reimbursement schemes and managing high-risk patients through coordinated care. ...
Breaking Medicine News(10 mins):Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 3Health News:Local Physicians Warn of Holiday Health Hazards 2Health News:Local Physicians Warn of Holiday Health Hazards 3Health News:Local Physicians Warn of Holiday Health Hazards 4Health News:79-Year-old ‘Pacing Parson’ Passes 1,000-Mile Mark in Cross-Country Walk for Pulmonary Hypertension Association 2Health News:79-Year-old ‘Pacing Parson’ Passes 1,000-Mile Mark in Cross-Country Walk for Pulmonary Hypertension Association 3Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 2Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 3Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 4
... By Steven Reinberg HealthDay Reporter , FRIDAY, Aug. ... now and then can,t hurt, right? Wrong, according to ... exposure can cause irreparable damage to cells essential to breathing. ... exposure to secondhand smoke. The initial damage, while not usually ...
... This release is available in French . ... women, while often unrecognised and underreported, have become the subject ... Female Sexual Offenders: Theory, Assessment and Treatment (Wiley), is the ... female-perpetrated sexual abuse, statistics on the crime, as well as ...
... If you want to know how people become addicted and ... addicted. Thirty-one of 75 patients hospitalized for opioid detoxification ... drugs legitimately prescribed for pain. , Another 24 began ... parent,s medicine cabinet. The remaining 20 patients said they got ...
... project at the Peninsula Medical School in Exeter, which will study ... eggs, gas) as an effective anti-inflammatory agent, has won a research ... H 2 S occurs naturally in the body and, when in ... good health. Last year the research team investigated the ...
... more commonly associated with the smell of ,rotten eggs, and ... present naturally in our bodies and reside in knee joint ... joints that reduces friction between the cartilage of joints during ... in reducing inflammation in joints. The research, carried out ...
... Elsevier Health Sciences and Helinet, India,s premier medical ... that will provide all medical students at Helinet,s ... local medical content through Elsevier,s electronic platforms: ScienceDirect ... provides all undergraduates, graduates, researchers and faculty within ...
Cached Medicine News:Health News:Study Finds Even a Little Cigarette Smoke Harms Airway 2Health News:Study Finds Even a Little Cigarette Smoke Harms Airway 3Health News:Female sexual offenders: Unrecognized and underreported 2Health News:Drug addicts get hooked via prescriptions, keep using 'to feel like a better person,' research shows 2Health News:Drug addicts get hooked via prescriptions, keep using 'to feel like a better person,' research shows 3Health News:Grant for 'rotten eggs' anti-inflammatory research 2Health News:'Rotten eggs' gas and inflammation in arthritic joints 2Health News:'Rotten eggs' gas and inflammation in arthritic joints 3
... quality control material that, once tonometered, is ... gas, electrolyte, metabolite, and CO-Oximeter instrumentation. It ... of human blood in tonometry. QC 463 ... monitoring analyzer performance at varying points within ...
... is a reagent and probe system used ... high throughput plate based system is a ... a unique approach for RNA detection and ... branched DNA (bDNA) technology. Branched DNA allows ...
... KMI Diagnostics is a CLIA-certified diagnostic ... hormones and a limited number of other ... programs across the United States. We ... research laboratory services and pre-clinical trials services. ...
For the qualitative detection of Hepatitis B surface Antigen (HBsAG) in human serum, plasma and whole blood specimens...
Medicine Products: