Navigation Links
Cell Therapeutics Announces Presentation of Interim Results from Phase 2 Tosedostat Trial in Older Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) at ASH Annual Meeting
Date:12/9/2013

SEATTLE, Dec. 10, 2013 /PRNewswire/ -- Cell Therapeutics, Inc. (CTI) (NASDAQ and MTA: CTIC) today announced promising interim results from an investigator-initiated Phase 2 clinical trial of tosedostat in combination with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). Tosedostat is a first-in-class selective inhibitor of aminopeptidases, which are required by tumor cells to provide amino acids necessary for growth and tumor cell survival. Tosedostat is administered orally and has been previously shown to induce complete remissions as monotherapy in relapsed or refractory AML. Researchers presented the findings from this combination study today for the first time at the 55th American Society of Hematology (ASH) Annual Meeting and Exposition held December 7–10 in New Orleans, La.

"Treatment outcomes for older patients with newly diagnosed AML remain poor," said John Pagel, M.D., Ph.D., Associate Member, Clinical Research Division, Fred Hutchinson Cancer Research Center; Associate Professor, Medical Oncology Division, University of Washington School of Medicine; and Principal Investigator in the tosedostat first-line AML/MDS trial. "This is the first time that tosedostat has been given in a front-line setting in combination with low intensity therapy. The complete response rates and median survival observed in previously untreated older patients with AML is promising and appears to be worthy of further clinical investigation." 

The Phase 2 trial was designed to test the efficacy of tosedostat in combination with low intensity therapy for older patients with previously untreated AML or high-risk MDS not considered candidates for standard intensive therapy. This presentation reported on the results of 26 patients (median age was 69) enrolled in t
'/>"/>

SOURCE Cell Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
3. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
4. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
5. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
6. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
7. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
8. Cara Therapeutics Licenses Novel Kappa Opioid Agonist, CR845, to Chong Kun Dang Pharmaceutical Corporation For South Korean Market
9. Frost & Sullivan: High Uptake of New Drug Therapies and Aging Population Expansion Keep the U.S. Retinal Therapeutics Market Buoyant
10. Zenobia Therapeutics, Inc. And BioBlocks, Inc. Announce Sale Of A Joint Fragment Library Ideal For Screening By All Popular Methods
11. New Forecast Shows Global Protein Therapeutics Market to Reach $143.4 Billion by 2015
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... , Oct. 22, 2014 AVACEN Medical ... device received 510 (k) OTC clearance by the U.S. ... 100 to be marketed over the Internet for: ... muscle spasms; and minor strains and sprains . ... The AVACEN 100 (MSRP $2495) is a sophisticated medical ...
(Date:10/22/2014)... -- Oramed Pharmaceuticals Inc. (NASDAQCM: ORMP) ... focused on the development of oral drug delivery ... its Phase IIa clinical trial of ORMD-0801, the ... 1 diabetes. The trial was conducted in ... Food and Drug Administration (FDA) Investigational New Drug ...
(Date:10/22/2014)... Influenza will affect as many as 200,000 people ... United States as high as 49,000 people.  The ... from person to person in respiratory droplets of coughs and ... death, but kills much fewer people each year than the ... fluids including sweat, saliva, blood and other bodily fluids. The ...
Breaking Medicine Technology:AVACEN Medical Announces FDA Clearance of First Medical Device with Internal Game Mode 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 4WholeHealth Products is proud to be releasing its Influenza A and B combo test, on the heels of the announcing of its phase 2 completion of the Rapid Ebola Test 2
... 2 Meeting with the FDA for the Fabry Program and Initiation ... ... Quarter, CRANBURY, N.J., Aug. 7 ... pharmacological chaperones for the treatment of human,genetic diseases, today announced financial results ...
... 7 The American Association of Diabetes,Educators ... conducted by Harris,Interactive highlighting communication between people ... healthcare providers. According to the,survey results, 33 ... of,dread relating to insulin injections (eight percent ...
Cached Medicine Technology:Amicus Therapeutics Announces Second Quarter 2008 Financial Results 2Amicus Therapeutics Announces Second Quarter 2008 Financial Results 3Amicus Therapeutics Announces Second Quarter 2008 Financial Results 4Amicus Therapeutics Announces Second Quarter 2008 Financial Results 5Amicus Therapeutics Announces Second Quarter 2008 Financial Results 6Amicus Therapeutics Announces Second Quarter 2008 Financial Results 7Amicus Therapeutics Announces Second Quarter 2008 Financial Results 8Amicus Therapeutics Announces Second Quarter 2008 Financial Results 9Amicus Therapeutics Announces Second Quarter 2008 Financial Results 10Amicus Therapeutics Announces Second Quarter 2008 Financial Results 11Amicus Therapeutics Announces Second Quarter 2008 Financial Results 12New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers 2New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers 3New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers 4
(Date:10/22/2014)... 22, 2014 Akeso Biomedical, Inc. ... the treatment of bacterial infections, microbial biofilms, and chronic ... its board of directors. , Dr. Sinskey ... at The Massachusetts Institute of Technology, or MIT. He ... 1968. Dr. Sinskey also holds positions as Co-Director of ...
(Date:10/22/2014)... Haelle HealthDay Reporter , TUESDAY, ... adult men may lead to increased blood pressure, according to ... similar rise in blood pressure for young adult women or ... adult women drank lightly or moderately, their risk of high ... "This finding parallels studies in older adult men and women," ...
(Date:10/22/2014)... HealthDay Reporter TUESDAY, Oct. 21, 2014 (HealthDay News) ... for NBC News in Liberia has cleared the virus ... Nebraska Medical Center in Omaha, where he had been treated for ... test confirmed by the U.S. Centers for Disease Control and Prevention ... NBC News reported Tuesday night. "Recovering from Ebola ...
(Date:10/20/2014)... The Advocator Group, LLC is proud ... for Suicide Prevention’s (AFSP) Out of the Darkness walk ... that hosts hundreds of community walks throughout the country ... to help understand and prevent suicide through not only ... , The Advocator Group shares this passion for ...
(Date:10/20/2014)... IN (PRWEB) October 20, 2014 ... Start, a secure cloud solution that enables healthcare ... of the ultimate healthcare-specific customer relationship management (“CRM”) ... meet the unique needs of the healthcare industry, ... experience for providers and patients by combining healthcare ...
Breaking Medicine News(10 mins):Health News:Akeso Biomedical Appoints Dr. Anthony J. Sinskey to Board of Directors 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 3Health News:Binge Drinking May Boost Blood Pressure in Young Men 4Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 2Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2
... , , , CARLSBAD, Calif., ... the leader in antisense therapeutics, today announced that management will present ... Conference on Tuesday, August 11, 2009, at 1:00 p.m. ET at ... audio webcast of the presentation will be available on the "Investors ...
... , , SPRING, ... pleased to advise the nutrition and investing community that its flagship ... corporate activities, are easily accessible by simply Googling Cholesterade(R). , ... recent updates on Go Healthy and/or its products, we are confident ...
... , , , , ... high-performance sports water , is targeting ... of major sporting events throughout the late summer and fall. ... cellular hydration in the most demanding environments, from professional sporting events ...
... ... UK have brought every major video conference endpoint manufacturer together for the ultimate in ... altogether under one roof and connect with MCU, Gateway, Firewall, Streaming & Recording infrastructure ... ...
... ... Web site with resources for people with disabilities coincides with Americans with Disabilities Act,s ... ... Americans with Disabilities Act, the U.S. Department of Labor has re-named and re-launched its ...
... , , WASHINGTON, ... announced that they have been chosen as the exclusive ... improvement program, called the IC3 Program(R) (Improving Continuous Cardiac ... Record (EHR) interfacing and data extraction process beginning with ...
Cached Medicine News:Health News:Go Healthy's Marquis Product Cholesterade(R) at Your Fingertips on Google 2Health News:AquaHydrate, First High Performance Sports Water, Targets So Cal Sports Market With Summer Event Support 2Health News:AquaHydrate, First High Performance Sports Water, Targets So Cal Sports Market With Summer Event Support 3Health News:The World of HD Video Conferencing is Now at VideoCentric - One-stop Comparisons of Tandberg, Polycom, Lifesize, Sony, Emblaze-VCON and Aethra 2Health News:The World of HD Video Conferencing is Now at VideoCentric - One-stop Comparisons of Tandberg, Polycom, Lifesize, Sony, Emblaze-VCON and Aethra 3Health News:The World of HD Video Conferencing is Now at VideoCentric - One-stop Comparisons of Tandberg, Polycom, Lifesize, Sony, Emblaze-VCON and Aethra 4Health News:Disability.gov Adds Social Media Tools, Disability Resources and a New Design to Complement Information from 22 Federal Agencies 2Health News:Disability.gov Adds Social Media Tools, Disability Resources and a New Design to Complement Information from 22 Federal Agencies 3Health News:Featherstone Informatics Group, Inc. Named Exclusive Vendor for the American College of Cardiology's Practice-Based Data Registry Program 2
Curved shafts with 2 mm angled platform. Wide serrated handle with dull finish....
Curved shafts with 3.5 mm angled platform and dull finish. Wide serrated handle with dull finish....
15 mm curved blade. 8 mm straight distal tip. Serrated on top of knife. Flat handle....
Grooved roller, on which knife oscillates....
Medicine Products: