Navigation Links
Catabasis Pharmaceuticals Announces Issuance of Patents for CAT-1000 and CAT-2000 Series
Date:4/30/2013

treat complex human diseases such as inflammatory and metabolic diseases."

About CAT-1004CAT-1004 is a new chemical entity that is a conjugate of the omega-3 fatty acid docosahexaenoic acid (DHA) and salicylate. Catabasis' lead program amplifies the beneficial effects of omega-3 fatty acids and salicylate to target inflammation, an underlying cause of many chronic diseases. A growing body of peer-reviewed research, along with clinical experience, has demonstrated important therapeutic benefits of DHA and eicosapentaenoic acid (EPA). Salicylates are anti-inflammatories with proven clinical efficacy and safety, and have been used safely for years to treat inflammatory bowel disease and other diseases of inflammation. Inhibition of NF-kB in muscle satellite cells has been hypothesized to have a beneficial effect in Duchenne muscular dystrophy. Catabasis recently announced positive Phase 1 data for CAT-1004 showing it was safe and well tolerated and that the technology allowed the active components to synergistically inhibit the NF-kB pathway. Phase 2 studies are being planned to evaluate the safety and efficacy of CAT-1004 in patients with inflammatory bowel disease and as a replacement for corticosteroids in patients with Duchenne muscular dystrophy.

About CAT-2003CAT-2003 is a new chemical entity that is a conjugate of the B vitamin niacin and eicosapentaenoic acid (EPA), an omega-3 fatty acid, linked using the company's proprietary SMART Linker technology. It is being investigated for the treatment of severe hypertriglyceridemia. In preclinical models of severe hypertriglyceridemia, a significant and dose-dependent reduction in plasma triglycerides was observed with CAT-2003, while a simple combination of niacin and omega-3 had only a marginal effect. In preclinical models of dyslipidemia, CAT-2003 dramatically reduced LDL cholesterol. In combination with a statin, CAT-2003 synergistically lowered LDL cholesterol. Because CAT-2003 is not activated unti
'/>"/>

SOURCE Catabasis Pharmaceuticals Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Catabasis Initiates Phase 1 Trial of CAT-2003 for Treatment of Severe Hypertriglyceridemia
2. Selexis SA Sells Rights to Royalty Payments for More Than 15 Biologic Development Programs to Ligand Pharmaceuticals
3. Oramed Pharmaceuticals to Present Results of its Key Clinical Studies of Oral Insulin in Type 1 Diabetes Patients at the GTC Diabetes Summit, Boston, MA; April 29-30, 2013
4. Auxilium Pharmaceuticals Completes Acquisition Of Actient Holdings LLC To Create A Leading Urology Franchise With A Diversified Product Portfolio And Strong Growth Profile
5. Absorption Pharmaceuticals to Receive Patent for Premature Ejaculation Topical Medication
6. Novartis Pharmaceuticals Corporation disputes allegations in two US Government lawsuits and looks forward to a fair discussion of the facts
7. Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Thursday, May 2
8. Avanir Pharmaceuticals Receives Positive CHMP Opinion for Approval of NUEDEXTA in Europe
9. Cumberland Pharmaceuticals To Announce First Quarter 2013 Financial Results On May 2, 2013
10. Horizon Technology Finance Closes $2 Million Venture Loan Facility with New Haven Pharmaceuticals
11. Auxilium Pharmaceuticals to Announce First Quarter 2013 Results and Conduct Conference Call on Monday, April 29, 2013
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... CARLSBAD, Calif., May 5, 2015 Isis Pharmaceuticals, ... operating income of $4.0 million for the three months ... net operating loss of $22.6 million for the same ... due to higher revenue from milestone payments earned from ... On a GAAP basis, Isis reported a loss from ...
(Date:5/5/2015)... 2015 Big Market Research presents a detailed ... Europe , ( France , Germany ... , UK) and Japan . Current scientific views ... provides the 5-year test volume and sales forecasts by country for ... Anti-HAV, Hepatitis Delta, HBc Ag, HBe Ag, and ALT/SGPT tests performed ...
(Date:5/5/2015)... 2015  Image Stream Medical, a leader in OR ... one of the largest group purchasing organizations, serving four ... terms of the three-year agreement, Image Stream,s portfolio of ... made available to MedAssets members beginning on July 1, ... Medical CEO Eddie Mitchell said, ...
Breaking Medicine Technology:Isis Reports Financial Results and Highlights for First Quarter 2015 2Isis Reports Financial Results and Highlights for First Quarter 2015 3Isis Reports Financial Results and Highlights for First Quarter 2015 4Isis Reports Financial Results and Highlights for First Quarter 2015 5Isis Reports Financial Results and Highlights for First Quarter 2015 6Isis Reports Financial Results and Highlights for First Quarter 2015 7Isis Reports Financial Results and Highlights for First Quarter 2015 8Isis Reports Financial Results and Highlights for First Quarter 2015 9Isis Reports Financial Results and Highlights for First Quarter 2015 10Isis Reports Financial Results and Highlights for First Quarter 2015 11Isis Reports Financial Results and Highlights for First Quarter 2015 12Isis Reports Financial Results and Highlights for First Quarter 2015 132015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 22015 Opportunities in the Global Hepatitis Diagnostic Testing Market: Big Market Research 3Image Stream Medical Announces Agreement with MedAssets 2
(Date:5/5/2015)... Sunny skies and cool temperatures made for great conditions last ... walkers participated in Global Lyme Alliance’s (GLA) inaugural “Lyme ... 5K and 10K runs and 1-and 3-mile walks were held ... for tick-borne disease research. The “Lyme Walk and Run” was ... of Lyme Research Alliance (LRA) and Tick-Borne Disease Alliance (TBDA), ...
(Date:5/5/2015)... May 05, 2015 Skedans Systems ... Victoria BC announced the Skedans Sensor Collaboration Platform at ... mobile and web app developers, provides tooling to deliver ... mobile sensors. , The Skedans Sensor Collaboration Platform is ... of the Internet of Things, Web Real Time Communications ...
(Date:5/5/2015)... year, PolyU researchers garnered two Grand Prizes, two Special ... and four Silver Medals at the world-renowned event. The ... Prize and Gold Medal with the Congratulations of Jury:, ... Investigator: Dr Allan Chee-kooi CHAN, Institute of Textiles and ... the “mannequin” for many tasks involved in apparel design, ...
(Date:5/5/2015)... 2015 ProTexting, LLC – a ... deploy Mobile Engagement Campaigns and other Mobile solutions, introduces ... can now leverage the power of Mobile Marketing to ... subscribers’ e-mail addresses into the Constant Contact Platform. , ... the growing trend of multi-channel marketing would become more ...
(Date:5/5/2015)... Rare Genomics Institute (RG) today announced ... determining how crowdfunding can promote scientific research to help ... rare disease patients with access to state of the ... and help for payment of these services through grants, ... how crowdfunding will not only help raise much needed ...
Breaking Medicine News(10 mins):Health News:1st Annual “Lyme Walk & Run” Event a Huge Success 2Health News:1st Annual “Lyme Walk & Run” Event a Huge Success 3Health News:Skedans Systems Announces Skedans Sensor Collaboration Platform at AUVSI's Unmanned Systems 2015 in Atlanta 2Health News:PolyU wins top prizes in Geneva’s Invention Expo 2Health News:PolyU wins top prizes in Geneva’s Invention Expo 3Health News:PolyU wins top prizes in Geneva’s Invention Expo 4Health News:PolyU wins top prizes in Geneva’s Invention Expo 5Health News:ProTexting SMS Mobile Marketing platform integrates with Constant Contact 2Health News:ProTexting SMS Mobile Marketing platform integrates with Constant Contact 3Health News:Rare Genomics Institute to Study Impact of Crowdfunding on Rare Diseases 2
... congratulates Jeffrey Crowley, an openly gay man with significant ... his appointment as Director of the Office of National ... dedicated team in the Executive Office of the President,s ... Barnes who has a long standing commitment to HIV/AIDS. ...
... best, south the worst; men and young adults also ... -- The federal government,s push to reduce motor vehicle ... in Massachusetts and the northeast getting the message loud ... -- particularly Mississippi -- are still dying in higher-than-acceptable ...
... Journal of Gerontology: Social Sciences reveals that ... elementary schools are not only more physically active than their ... time. Specifically, those who volunteered burned twice as many calories ... led by Erwin Tan, PhD, of the Johns Hopkins University, ...
... Ltd, B2B, SEO Online PR & Marketing Consultancy, is pleased to ... its already successful Industry Directory, offering free listings to relevant specialist ... ... Marcomms Ltd, B2B, SEO Online PR & Marketing Consultancy , ...
... WASHINGTON, Feb. 26 The chief executive of ... Senate subcommittee today, addressing an alarming new report ... a dangerous shortage of veterinarians available to fill ... DeHaven, CEO of the American Veterinary Medical Association ...
... In the past 12 weeks, two ... Lifesaver, a nationwide tracking program established to quickly locate ... disabilities, such as autism and Alzheimer,s. The program is ... two fathers of children with autism, Sam Spencer and ...
Cached Medicine News:Health News:AIDS Action Applauds President on Appointment of Jeffrey Crowley as Director of National AIDS Policy 2Health News:Car-Crash Death Rates Depend on Where You Live in U.S. 2Health News:Older women find health benefits through volunteer program 2Health News:Simply Marcomms Launch New Specialist Online Industry Directories 2Health News:AVMA Testifies at Senate Hearing on GAO Veterinary Shortage Report 2Health News:AVMA Testifies at Senate Hearing on GAO Veterinary Shortage Report 3Health News:Local Communities Get Serious About Saving Lives Through Project Lifesaver Tracking Equipment, Says NAA 2
... The Super 66® Stereo Fundus ... magnification viewing of the central retina. Its ... subtle macular and optic disc detail, making ... choroidal neovascular membranes, macular edema, serous detachments ...
... The original Volk 90D lens started the ... small 26mm diameter ring design which is ... Aspheric optical design expands the usable viewing ... Volk 90D has good small pupil capabilities, ...
The Volk 60D provides high magnification - making it ideal for detailed disc and macular viewing. Its 31mm diameter facilitates easy handling within the orbital area. Available with SupraCoat (argon...
The 40D is ideal for pediatric ophthalmoscopy and other examinations requiring expansive fundus visibility. Alternatively, this lens may be used at the slit lamp biomicroscope to provide an extremely...
Medicine Products: