Cardium Reports Non-Healing Wounds Continue to Challenge Patients and Healthcare...(events.powerstream.net/002/00432/player/...),Health

Date:8/27/2009

events.powerstream.net/002/00432/player/start.asp?mediaformat=asx&bitrates=100%3B34&bitratetxt=HIGH+BANDWIDTH%3BLOW+BANDWIDTH&mediahost=http%3A%2F%2Fpowerlink%2Epowerstream%2Enet&w=349&h=400&clip=1&contID=MatrixTrial&bypass=" target="_new">click here to view a segment featuring Dr. Peter A. Blume, DPM, FACFAS, of the Yale University School of Medicine, and their patients enrolled in the MATRIX clinical study. The MATRIX study media segments can also be accessed at www.cardiumthx.com.

Orthobiologics Initiative

Cardium recently announced its plans to develop a DNA-based orthobiologics product portfolio based on research and development that will initially focus on non-union bone fractures for medically-compromised patients, and spinal fusions for patients with degenerative disc disease. Orthobiologics is a rapidly growing segment of the orthopedics market and represents biologically-active products designed to enhance musculo-skeletal repair and regeneration. The initial orthobiologics focus will be on the development of Osteorate(TM), a DNA-based non-surgical injectable bone graft gel to repair bone fractures and regenerate tissue in certain medically-compromised patient populations. Osteorate will be based on reformulation of Cardium's DNA-based Excellarate wound healing product candidate, which is designed to stimulate localized and sustained cellular production of platelet-derived growth factor-B (PDGF-B) protein, as a treatment for patients with non-healing diabetic foot ulcers. The Gene Activated Matrix technology allows for a broad spectrum of biocompatible matrix formulations which would include, but not be limited to, collagen, demineralized bone, allograft and synthetic graft materials.

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