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Cardium Presents Year-End 2012 Financial Results And Recent Developments
Date:4/5/2013

rketing and distribution of Excellagen in the South Korean market; and (2) Advanced Biosciences Research, an affiliate of bioRASI, for the planned commercialization of Excellagen in the Russian Federation and CIS;
  • Advanced forward with applications to support the reimbursement process for Excellagen with the Centers for Medicare & Medicaid Services (CMS) and private insurance providers, and broadened marketing and sales efforts into markets with established CPT® codes for surgical debridement procedures and in-hospital surgical markets covered under DRG reimbursement systems.
  • Advancing Generx Phase 3 Angiogenic
    Gene Therapy Product Candidate

  • Initiated the ASPIRE Phase 3 registration study, a 100-patient randomized and controlled multi-center study being conducted at leading cardiology centers in Russia, and designed to evaluate the therapeutic efficacy of the Company's Generx® (Ad5FGF-4) DNA-based angiogenic growth factor therapeutic for patients with myocardial ischemia due to coronary artery disease; 
  • Published important Generx findings in the peer-reviewed journal Human Gene Therapy Methods demonstrating that Cardium's innovative technique employing transient cardiac ischemia can be used to dramatically enhance gene delivery and transfection efficiency after a one-time intracoronary administration of adenovector in mammalian hearts.  The findings have been incorporated into the treatment protocols of the Generx ASPIRE Phase 3 study; 
  • Presented at the 2013 Phacilitate Annual Cell & Gene Therapy Forum held in Washington, DC, "Optimizing Phase III Trial Design for Generx (Ad5FGF-4)" on adaptive coronary collateral growth, the biological processes to be targeted by therapeutic angiogenesis, and discussed the lessons learned during the past decade of the Co
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