Navigation Links
Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process
Date:10/13/2010

SAN DIEGO, Oct. 13 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM) today reported on new preclinical research findings that Excellagen, a topically applied formulated collagen wound management gel product candidate, activates platelet release of platelet-derived growth factor (PDGF) locally at the wound site.  This growth factor has been shown to play an essential role in the wound healing process.

(Logo:  http://photos.prnewswire.com/prnh/20051018/CARDIUMLOGO)

(Logo:  http://www.newscom.com/cgi-bin/prnh/20051018/CARDIUMLOGO)

This research effort was undertaken for Cardium by an independent contract testing laboratory in an effort to further understand the statistically significant accelerated wound healing (as measured by the overall reduction in wound radius) in chronic diabetic foot ulcers that was observed in Cardium's Matrix clinical study during the first two weeks following administration of Excellagen formulated collagen (2.6%) topical gel, compared to the study's standard of care arm.   In addition, detailed reviews of previous preclinical studies, the Matrix clinical study protocol and Excellagen application practices were undertaken.

Based on data from this new research study and review, Cardium researchers now believe that the Excellagen product candidate activates the release of PDGF (and potentially other important growth factors) from platelets that migrate into the wound site with the influx of blood resulting from surgical wound debridement, a procedure that is commonly used by physicians and wound care specialists as a component of standardized wound care.  In the Matrix clinical study, Excellagen formulated collagen was applied immediately following debridemen
'/>"/>

SOURCE Cardium Therapeutics
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Cardium and Tissue Repair Companys Excellarate Candidate for Healing Diabetic Wounds Gains Media Focus in Multiple Regions Across U.S.
2. Cardiums Innercool Therapies Unit Announces Publication of Positive Effects of Early and Rapid Hypothermia Following Heart Attack
3. Cardium Announces Appointment of Paul A. Foster, M.D. to Lead Generx and Excellarate Late-Stage Development Activities
4. Cardium Reports on Second Quarter 2008 Highlights and Financial Results
5. Cardiums InnerCool Announces Positive Benefits of Cooling During Robotic-Assisted Prostate Surgery Published in Urology
6. Cardium Reports on Applicability of Corgentin to Stem Cell Therapies: Independent Studies Indicate that Ad5IGF-1 Potentiates Stem Cells to Improve Cardiac Function After Heart Attack
7. Cardium Announces Completion of Patient Recruitment in Phase 2b Clinical Trial of Excellarate(TM) for the Potential Treatment of Diabetic Foot Ulcers
8. Cardium Completes Initial Patient Evaluation Period for MATRIX Phase 2b Excellarate Clinical Study
9. Cardium Reports Non-Healing Wounds Continue to Challenge Patients and Healthcare Providers
10. Cardium Presents at Tenth Annual Wound Healing: Science and Industry Conference on Matrix Wound Healing Clinical Development
11. Cardium Files FDA 510(k) Application for U.S. Marketing Clearance of ExcellagenXL(TM) Topical Gel and ExcellagenFX(TM) Flowable Collagen Protein-Based Matrix for Diabetic, Pressure and Venous Ulcers and Other Dermal Wounds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... Research and Markets  has announced the addition ... report to their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... to inflammation and pain in the human body,s joints such ... causes inflammation of the tissues that surround the joints and ... RA begin slowly, usually just mild pain around the joints ...
(Date:7/28/2014)... -- Syneron Medical Ltd. (NASDAQ: ELOS ), a ... new PicoWay® device has received CE Mark indication to ... lesions on any skin type. PicoWay is a new ... wavelengths, which utilizes Syneron,s proprietary PicoWay technology to deliver ... of a second, known as picosecond pulses. Syneron will ...
(Date:7/28/2014)... -- Concord Medical Services Holdings Limited ("Concord Medical" or ... specialty hospital management solution provider and operator of the ... China , today announced that on ... special cash dividend of US$0.30 per ordinary share (or ... outstanding ordinary shares. The total expense for the special ...
Breaking Medicine Technology:Global Rheumatoid Arthritis Drugs Market 2014-2018 2Syneron Announces CE Mark for PicoWay Dual Wavelength Picosecond Laser for Tattoo Removal and Treatment of Pigmented Lesions 2Syneron Announces CE Mark for PicoWay Dual Wavelength Picosecond Laser for Tattoo Removal and Treatment of Pigmented Lesions 3Syneron Announces CE Mark for PicoWay Dual Wavelength Picosecond Laser for Tattoo Removal and Treatment of Pigmented Lesions 4Concord Medical Declares Special Dividend 2
... PORTSMOUTH, N.H., Aug. 4, 2011 Novocure, a ... it has entered into a long-term supply agreement ... engineering and manufacturing conglomerate ITT Corporation (NYSE: ITT). ... ceramic components used to manufacture the disposable electrodes ...
... Texas, Aug. 4, 2011 Healthpoint Biotherapeutics today ... clinical trial investigating the efficacy of HP802-247 in ... living cell suspension containing keratinocytes and fibroblasts. The ... of two cell concentrations and two dosing frequencies ...
Cached Medicine Technology:Novocure Announces Long-Term Supply Agreement With ITT Corporation for Ceramic Sensor Technology 2Novocure Announces Long-Term Supply Agreement With ITT Corporation for Ceramic Sensor Technology 3Positive Results for Phase IIb Trial of Unique Cell-Based Therapy in Venous Leg Ulcers 2Positive Results for Phase IIb Trial of Unique Cell-Based Therapy in Venous Leg Ulcers 3Positive Results for Phase IIb Trial of Unique Cell-Based Therapy in Venous Leg Ulcers 4
(Date:7/28/2014)... Cape Regional Medical Center, is ... technology solution in an effort to streamline its ... with their New Jersey health information exchange (NJSHINE). ... in New Jersey, serves the local population and ... of inpatient and outpatient services. With a strong ...
(Date:7/28/2014)... 28, 2014 (HealthDay News) --,The more chronic medical conditions ... expectancy may be, a new study claims. ... health issues, scientists at Johns Hopkins Bloomberg School of ... explain why gains in life expectancy are slowing in ... such as diabetes, kidney disease and heart failure is ...
(Date:7/28/2014)... Reinberg HealthDay Reporter MONDAY, ... and heart rhythm irregularities are more likely to get a ... In fact, the study of more than 16,000 people found ... likely to get a pacemaker than those without the memory-robbing ... why folks with dementia are so much more likely to ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 Parker Waichman LLP, ... fighting to ensure that the heroes of 9/11 are never ... has announced an important deadline. According to a VCF ... with a covered cancer on or before October 12, 2012 ... 2014. First responders and others who were allegedly injured by ...
(Date:7/28/2014)... expecting somethinglike the meal you,ve ordered at a ... rhythms sweep through your brain. , These ... a symphony of cellsboth excitatory and inhibitoryplaying together ... been debated, gamma waves have been associated with ... have been tied to schizophrenia, Alzheimer,s disease, autism, ...
Breaking Medicine News(10 mins):Health News:Cape Regional Medical Center Chooses Summit Provider Exchange to Connect With NJSHINE and Physician Offices 2Health News:Cape Regional Medical Center Chooses Summit Provider Exchange to Connect With NJSHINE and Physician Offices 3Health News:Chronic Medical Conditions Can Shorten Seniors' Lives: Study 2Health News:Pacemakers Common for Those With Dementia and Irregular Heartbeats 2Health News:Pacemakers Common for Those With Dementia and Irregular Heartbeats 3Health News:October 12, 2014 Deadline Approaching for 9/11 First Responders Suffering from Certain Cancers to Submit Their Registration to the VCF, Parker Waichman LLP Comments 2Health News:October 12, 2014 Deadline Approaching for 9/11 First Responders Suffering from Certain Cancers to Submit Their Registration to the VCF, Parker Waichman LLP Comments 3Health News:Memory relies on astrocytes, the brain's lesser known cells 2Health News:Memory relies on astrocytes, the brain's lesser known cells 3
... in mice shows promise for possible use in treating Alzheimer's ... study. ,Alzheimer's disease is the most common form of ... speech deterioration, and behavioral changes. The main factor in the ... toxic to the brain. ,Researchers say they have found ...
... steps you take to prevent heart attack may also ... risk factors like high blood pressure and high cholesterol ... and can cause death of brain cells over time. ... designed to slow the progression of mixed dementia, vascular ...
... Researchers say most of the existing drugs on the ... are derived from soil bacteria hence researchers feel that ... miracle drugs.// ,More than 1 million microorganisms ... to a life-saving treatment for some of our deadliest ...
... have identified a protein that essentially blocks HIV replication, ... it is not as effective at stopping HIV, say ... issue of Nature. The team, headed by Joseph Sodroski, ... and Infectious Diseases (NIAID). ,"Identification of this ...
... have optic nerve damage are at increased risk for ... with visual impairment. The participants had their sleep-wakefulness cycles ... with those of 12 young subjects with normal sight. ... more likely to have daytime sleepiness than those with ...
... panoramic X-rays can identify postmenopausal women with low skeletal ... taken for the diagnosis of conditions affecting the teeth ... the mandibular cortical shape and width and refer the ... more than 300 women who had no symptoms of ...
Cached Medicine News:
... 2.2 offers extremely high resolution treatment capability ... an exceptionally wide 78° field of view. ... critical evaluation of the optic nerve head ... of the macula and disc. Redesigned to ...
... is excellent for critically evaluating and ... macular degeneration, retinal vascular occlusions, diabetic ... other retinal conditions. It is ideal ... conditions providing excellent magnification combined with ...
... 130° QuadrAspheric lens has grown in popularity ... preferred wide field fundus laser lens. Its ... advantage over competitive wide field lenses for ... of use. This lens is excellent for ...
... Wide Field Lens combines exceptional ... magnification. The enhanced double aspheric ... high resolution stereo views of ... These unique features make it ...
Medicine Products: