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Cardium Announces Generx Publication In Molecular Therapy
Date:5/2/2013

SAN DIEGO, May 2, 2013 /PRNewswire/ -- Cardium Therapeutics (NYSE MKT: CXM) today announced a publication, "Mechanistic, Technical, and Clinical Perspectives in Therapeutic Stimulation of Coronary Collateral Development by Angiogenic Growth Factors", authored by Gabor M Rubanyi, M.D., Ph.D., Cardium's Chief Scientific Officer in the April issue of Molecular Therapy.  The publication outlines current scientific knowledge about the mechanistic basis of adaptive coronary collateral growth, the biological processes to be targeted by therapeutic angiogenesis, and the optimization of clinical trial designs, including the selection of appropriate clinical trial endpoints, selection of patients who are likely responders to therapeutic stimulation of collateral development, and potential genetic and molecular markers in patient screening.  The abstract of the publication is now available at   www.nature.com/mt/journal/v21/n4/abs/mt201313a.html (membership required for full viewing).  The Company will mail the full article to interested parties upon request by contacting Cardium at 858-436-1000.   

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"In this recent publication, I have summarized the lessons learned during the past 15 years of pre-clinical and clinical research and development efforts in the field of therapeutic angiogenesis using growth factor proteins and genes. I also described in some detail the specific insights that our team, first at Schering AG (now part of Bayer Healthcare) and now at Cardium, has gained in the course of the development of Generx, one of the most advanced therapeutic angiogenesis product candidates.  These lessons have been invaluable and they have been incorporated into the trial des
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