Navigation Links
Cardioxyl Pharmaceuticals Initiates Dose-Defining Phase IIa Study of Its Lead Candidate, CXL-1020, in Heart Failure Patients
Date:8/26/2010

reatment OptionsADHF is the leading diagnosis at the time of discharge from U.S. hospitals and the most common cause of hospitalization for patients over 65 years of age.(i) Well over $39 billion was spent in the U.S. in 2009 for the medical care of heart failure patients. ADHF is a deadly condition, with in-hospital mortality rates of two to six percent and six-month readmission rates as high as 30 to 60 percent.  Episodes of ADHF are marked by a severe reduction of cardiac function that typically results in fluid accumulation in the lungs (pulmonary edema) and consequent severe shortness of breath.  There were 1.1 million hospitalizations for acute heart failure in the U.S. in 2006.  Among patients hospitalized with ADHF, the 30-day mortality rate is approximately 11 percent and the one-year mortality rate is 34 percent.  These poor outcomes indicate the clear need for better therapies to treat this patient population.

Despite the severity of the condition, the treatment options available for patients with ADHF remain limited.  Current first-line treatments target the removal of excess fluid (diuresis) and preload and afterload reduction (vasodilation).  In order to improve the hemodynamic profile of the heart and increase cardiac contractility, a physician may also administer an intravenous inotropic agent such as dobutamine (beta-adrenergic agonist) or milrinone (PDE3-inhibitor).  Administration of dobutamine or milrinone often requires very close monitoring in the hospital's cardiac or intensive care unit setting due to the life-threatening safety risks associated with these drugs, including ventricular/atrial arrhythmias, hypotension, sudden cardiac death, and other potential adverse long term outcomes.(ii),(iii)

About Cardioxyl Pharmaceuticals Cardioxyl Pharmaceuticals is a clinical-stage pharmaceutical company focused on the discovery and development of new classes of safe and effective therapeutic agents f
'/>"/>

SOURCE Cardioxyl Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Lotus Pharmaceuticals Enter R-Bambuterol(R) Clinical Trial I
2. Jiangbo Pharmaceuticals Chairman to Ring NASDAQ Opening Bell on August 27, 2010
3. Actelion Pharmaceuticals Announces FDA Approval of Brand Name for Commercially Available VELETRI® (epoprostenol for injection) for Pulmonary Arterial Hypertension
4. China Yongxin Pharmaceuticals Reports Second Quarter 2010 Results
5. Jazz Pharmaceuticals Provides Update on FDA Advisory Committee Meeting For JZP-6 (Sodium Oxybate) in Fibromyalgia
6. Cumberland Pharmaceuticals Announces Extension of FDA Review of Acetadote® Supplemental New Drug Application
7. Shareholder Class Action Filed Against SciClone Pharmaceuticals, Inc. by the Law Firm of Barroway Topaz Kessler Meltzer & Check, LLP
8. Optimer Pharmaceuticals Fidaxomicin Marketing Authorization Application Accepted for Review by European Medicines Agency
9. Quark Pharmaceuticals and Major Pharmaceutical Company Enter into Licensing Option Agreement for the p53 Suppressor Drug QPI-1002, the First siRNA Administered Systemically in Human
10. Biostar Pharmaceuticals, Inc. Second Quarter Revenue Increased 46.4% to $19.4 Million
11. Trubion Pharmaceuticals Inc. Reports Second-Quarter and First-Half 2010 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2015)... , May 1, 2015 Hitachi Chemical Diagnostics, ... States launch of the ExoComplete™ 96-Well Plate ... easy system for exosome collection to mRNA purification.  The ... Vesicles ("ISEV") Annual Meeting, April 23 – 26, 2015, ... are intended for research use only of molecular biology ...
(Date:5/1/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/63gppw/asian_dermatology ) ... Market by Type, by End User - Forecast to 2019" ... Devices market is estimated to grow at a CAGR of ... holds a larger share in the Dermatology devices market around ... The Asian Dermatology Devices market holds a high potential for ...
(Date:5/1/2015)... --  Heska Corporation (NASDAQ: HSKA - ... advanced veterinary diagnostic and other specialty veterinary products , today ... at the 16th Annual B. Riley & Co. Investor Conference ... will be held May 12-14, 2015 at Lowes Hollywood Hotel, ... be available during the day on May 13 for one-on-one ...
Breaking Medicine Technology:New Products for Exosome Isolation to mRNA Purification 2Asian Dermatology Devices (Treatment & Diagnostic) Market by Type, by End User - Forecast to 2019 2Asian Dermatology Devices (Treatment & Diagnostic) Market by Type, by End User - Forecast to 2019 3Heska to Present at the 16th Annual B. Riley & Co. Investor Conference 2
... Pharmaceuticals Inc. (NASDAQ: VNDA ) announced ... Vanda,s sublicensor Novartis Pharma AG, has initiated a ... depot) formulation of Fanapt® (iloperidone).  This is a ... and pharmacokinetic profiles of two different long-acting formulations ...
... Noverca – the first and currently only Italian ,Full ... presence in the Health and Wellness Sector . ... has been developed and launched thanks to the long-term ... o verca) and Fatebenefratelli Hospital. Davide ...
Cached Medicine Technology:Vanda Pharmaceuticals Announces Commencement of Clinical Study of Long-Acting Injectable Formulation of Fanapt® 2Vanda Pharmaceuticals Announces Commencement of Clinical Study of Long-Acting Injectable Formulation of Fanapt® 3EXTENDED HEALTH: Noverca Enters the World of Healthcare 2
(Date:5/4/2015)... (PRWEB) May 04, 2015 ... just released the first-ever congenital heart disease ... Catheterization Laboratory (PCCL) accreditation. Driven by the ... are a comprehensive review of interventional procedures ... heart disease. , “The ACE CHD Standards ...
(Date:5/4/2015)... Sara Soulati, CEO of Global ... in Los Angeles associated with the field of Enhanced ... The Sara Soulati Health For Life Program (SSHFLP). , ... lifestyle modification and disease prevention program. A provisional ... S. Patents and Trademarks Office and is now under ...
(Date:5/3/2015)... VEGAS and LOS ANGELES, American Telemedicine Association 2015 ... vitaphone e-health solutions, a full-service telemedicine ... launch of its new platform, VITA health services ... The VITA health services platform enables remote patient ... such as congestive heart failure (CHF), diabetes, COPD, ...
(Date:5/3/2015)... “ BolehVPN ” was featured on NewsWatch ... latest and coolest technology products available to consumers. Scott Steinberg, ... review and shared with viewers how to protect their private ... is on computers and even more so online. It helps ... all over the world. In terms of work, the internet ...
(Date:5/3/2015)... (PRWEB) May 03, 2015 It is not too ... Brain Aneurysm Walk in Memory of Lissa Anne Been in ... organized this great family-friendly event to honor her loving memory. It ... inception. , Just having turned 37, Lissa suffered a ... away on August 24, 2012. This event is designed to serve ...
Breaking Medicine News(10 mins):Health News:Accreditation for Cardiovascular Excellence (ACE) Publishes New Standards for Pediatric and Adult Congenital Cardiac Catheterization Laboratories 2Health News:CEO Sara Soulati Announces Patent-Pending Designation For The Sara Soulati Health For Life Program 2Health News:vitaphone e-health solutions U.S. Announces VITA Health Services for Remote Chronic Disease Management 2Health News:vitaphone e-health solutions U.S. Announces VITA Health Services for Remote Chronic Disease Management 3Health News:A Method to Keep Private Information Secure was Featured on NewsWatch Television 2Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2
... invented at The University of Texas M. D. Anderson Cancer ... III clinical trial for cancer, as announced today at the ... , Introgen Therapeutics, Inc., reported results of its phase III ... gene p53, for end-stage head and neck cancer. , "Cells ...
... select winning online health applications, REDMOND, ... award funding from $3 million to $4.5 ... academic and research health,organizations across the United ... Proposals represent a wide range of innovative ...
... 28 The Gladney Center,for Adoption, Fort Worth, ... Melson to the newly-created position of Executive Vice ... responsible for creating,managing and implementing funding programs that ... bright futures around the globe through,adoption programs and ...
... 28 VirtualHealth,Technologies, Inc. (OTC Bulletin Board: VHGI) ... of Operations effective immediately. Robert,previously served as COO ... past 4 years,and joined VHGI as part of ... Robert has over 21 years experience in the ...
... May 28 At today,s Altria,(Philip Morris USA) ... against public health and tobacco control,measures. America,s largest ... Act recently introduced in the U.S. House of,Representatives ... labeling, tracking and reporting by the tobacco industry., ...
... May 2008 - You went to a wedding yesterday. The ... was dancing all night. But people tell you that you ... weeks, and that you didnt go to a wedding yesterday ... this following neurological damage is known as confabulation. The reasons ...
Cached Medicine News:Health News:Gene therapy increases survival for end-stage head and neck cancer 2Health News:Gene therapy increases survival for end-stage head and neck cancer 3Health News:Gene therapy increases survival for end-stage head and neck cancer 4Health News:Microsoft HealthVault Be Well Fund Increased to $4.5 Million 2Health News:Microsoft HealthVault Be Well Fund Increased to $4.5 Million 3Health News:Microsoft HealthVault Be Well Fund Increased to $4.5 Million 4Health News:Microsoft HealthVault Be Well Fund Increased to $4.5 Million 5Health News:The Gladney Center for Adoption Names Mark L. Melson as Executive Vice President/Chief Development Officer 2Health News:VirtualHealth Technologies, Inc. Announces Management Appointment 2Health News:Shareholders Demand Philip Morris USA Stop Interfering in Health Policy 2
Sharp tip with cutting edge bent to 45 degrees. Fits 19 gauge or 20 gauge instrument port. 21 gauge x 25 mm. 10 per box....
80 inch PVC tubing with connectors and 19 gauge straight, beveled cannula. Fits Bausch & Lomb Surgical cassettes. Allows the safe removal of silicone oil in 10 minutes or less. 3/Box...
Angled, cannula with 32 gauge tip, 4 mm long, angled 65 degrees 1 mm from tip. 10 per box....
Accommodates either eye. Slotted, malleable aluminum surface. Correct size holes produce ideal pin hole effect. Packaged 50 per box....
Medicine Products: