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Cardiovascular Researchers Use MEDIHONEY(TM) on Sternal Infections Following Open-Heart Procedures
Date:5/13/2008

iovascular and Thoracic Surgery as a special publication of the Journal of the Thoracic and Cardiovascular Surgeon. The investigators reported that there were no local or systemic adverse reactions to the treatment and that all patients progressed to complete wound healing. In the six patients who received application of MEDIHONEY every four days, the wounds were clean and sterile after a mean duration of treatment of 23 days. The two patients that received fewer applications of MEDIHONEY showed repeat positive wound cultures. No nosocomially acquired "superinfections" (including MRSA and VRE) were seen.

To read the abstract, please go to: http://www.thieme-connect.com/ejournals/abstract/thoracic/doi/10.1055/s-2008-1038073 (Information in this article concerns a use that has not been cleared by the US Food and Drug Administration.)

About deep sternal wound infections

Deep sternal wound infections occur in roughly 0.8% to 2% of patients undergoing median sternotomy and CABG. This rate increases to as high as 5.6% for diabetic patients, who make up between 17% and 20% of all patients undergoing CABG surgery. DSWI is associated with an average hospital stay increase of 16 days (average cost of over $25,000) and a higher mortality rate (19% versus 3.8% in patients without infection). Although the number of CABG procedures had been in decline since 2000 due to the advent of percutaneous coronary interventions (PCI) and drug-eluting stent (DES) procedures, recent questions into the safety and efficacy of these procedures has led to a 0.9% growth in CABG procedures. Approximately 800,000 to 1 million CABG procedures are performed globally each year. The worldwide CABG market is roughly $36 billion.

About Derma Sciences

Derma Sciences is a global manufacturer and marketer of advanced wound-care products. Its key produc
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