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Cardiovascular Drug Delivery - Technologies, Markets and Companies
Date:11/30/2011

s of cardiovascular drug delivery 154

7. Companies involved in Cardiovascular Drug Delivery 155

Profiles of companies 155

Collaborations 241

8. References 245

List of Tables

Table 1 1: Landmarks in the historical evolution of cardiovascular drug delivery 13

Table 1 2: Gene polymorphisms that alter cardiovascular response to drugs 18

Table 2 1: Routes of drug delivery used for treatment of cardiovascular disorders 25

Table 2 2: Formulations for drug delivery to the cardiovascular system 27

Table 2 3: Improved methods of systemic drug delivery of cardiovascular drugs 32

Table 2 4: Targeted delivery of therapeutic substances to the cardiovascular system 35

Table 2 5: Classification of devices for drug delivery to the cardiovascular system 36

Table 2 6: Various methods of delivery of therapeutic agents for hypertension 41

Table 2 7: Marketed controlled/ extended release preparation for hypertension 43

Table 2 8: Drug delivery in ischemic heart disease 45

Table 2 9: Methods of delivery of nitrate therapy in angina pectoris 49

Table 2 10: Drug delivery for peripheral arterial disorders 54

Table 3 1: Clinical trials of cell therapy in cardiovascular disease 73

Table 4 1: Cardiovascular disorders for which gene therapy is being considered. 79

Table 4 2: Catheter-based systems for vector delivery to the cardiovascular system 80

Table 4 3: Potential applications of antisense in cardiovascular disorders 99

Table 4 4: Companies involved in gene therapy of cardiovascular diseases 104

Table 5 1: Treatment of restenosis 108

Table 5 2: Devices used for drug delivery in restenosis 114

Table 5 3: Companies involved in drug-eluting stents 124

Table 6 1: Prevalence of cardiovascular disorders in major markets: US 2010-2020 146

Table 6 2: Prevalence of cardiovascular disorders in major markets:
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