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Cardiogenesis Announces Presentation of its PHOENIX(R) Combination TMR Plus Stem Cell Delivery System at the International Society of Minimally Invasive Cardiothoracic Surgeons (ISMICS) Annual Meeting
Date:6/4/2009

IRVINE, Calif., June 4 /PRNewswire-FirstCall/ -- Cardiogenesis Corporation (Pink Sheets: CGCP) the market leader in laser transmyocardial revascularization (TMR) for the treatment of chronic cardiac ischemia, announces that Dr. Naresh Trehan of New Delhi will be presenting his clinical results of combining laser TMR and stem cells to treat regions of myocardium that could not be revascularized by conventional methods. Eight patients treated with the PHOENIX System completed 1 year follow up:

  • Seven patients had concomitant coronary bypass grafting, one patient stand alone therapy.
  • There was no operative or hospital mortality. One year survival was 100%.
  • Compared to baseline, patients had NYHA Class improvement (Mean 3.5+/-0.5 to 1.33+/- 0.5, p= 0.001), and improved six minute walk test: 250+/- 112.1 seconds to 360+/-10 seconds, p=0.01.
  • MRI showed improved perfusion in the regions of myocardium treated by the PHOENIX System

The PHOENIX combination delivery system is CE Mark approved and has been used in over 50 procedures at cardiac centers outside the U.S. It is not currently FDA approved. The abstract "One Year Follow up of Combined Autologous Bone Marrow Derived Progenitor Cell Therapy and Transmyocardial Laser Revascularization for Diffuse Nongraftable Coronary Artery Disease" can be located at: http://www.ismics.org/abstracts/2009/10.html.

"These results add to the growing body of evidence that TMR has a positive impact on the intramyocardial delivery of biologics, such as stem cells. The PHOENIX System is designed to create transmural laser channels and with its three integrated injector needles, deliver the biologic into the surrounding t
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SOURCE Cardiogenesis Corporation
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