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CardioDx Completes Validation Study of First-Of-Its-Kind Genomic Test for Coronary Artery Disease
Date:8/25/2009

er individualize patient care.

"Our decision to develop Corus CAD was derived from many physician interactions in which they stressed the importance of and current challenges with effectively assessing obstructive CAD in patients with stable chest pain," said Levison. "We envision that a non-invasive, objective, easy-to-use test such as Corus CAD will empower physicians to more confidently identify which of these patients may have obstructive CAD."

About Corus CAD

Corus CAD is a clinically validated genomic test that integrates the expression levels of 23 genes and other patient characteristics to assess obstructive CAD. The test is intended to be used in an outpatient setting with clinically stable, non-diabetic patients who present with chest pain or who have a high risk of coronary artery disease, but without previously diagnosed myocardial infarction (heart attack) or prior revascularization procedure. Corus CAD is convenient and safe, and only requires a standard blood draw procedure. The test yields an objective result delivered to the physician in the form of a numeric score that quantifies the likelihood that a patient with stable chest pain has obstructive CAD.

Clinical Data

CardioDx designed a rigorous scientific plan and a prospective, nationwide, multi-center clinical study, PREDICT (Personalized Risk Evaluation and Diagnosis in the Coronary Tree, www.clinicaltrials.gov) to develop and validate Corus CAD. The PREDICT study sought to determine whether a gene expression test could be developed to identify obstructive CAD in patients with stable chest pain. The company has collected more than 2,800 patient samples in PREDICT from more than 40 clinical sites in the United States as of April 2009. Trial results and the Corus CAD validation data are expected to be presented toward the end of 2009.

About Obstructive CAD

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SOURCE CardioDx
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