Navigation Links
Cardio3 BioSciences Announces Promising Pre-Clinical Data for Proprietary C-Cath(R) Catheter

MONT-SAINT-GUIBERT, Belgium, March 2, 2010 /PRNewswire/ -- Cardio3 BioSciences, a leading Belgian biotechnology company specialising in cell-based therapies for the treatment of cardiovascular diseases, announced today promising results in a pre-clinical study of its proprietary C-Cath(R) catheter which is under development to administer a range of bio-therapeutics to the heart. C-Cath is designed to take into account organ tissue structure and properties to maximize patients' safety, improve performance and increase user confidence during the injection procedure.

The study was a head-to-head comparison between the current 'gold standard' injection catheter and C-Cath in injecting mesenchymal stem cells originating from bone marrow in an animal model widely used in cardiology studies. The study was carried out by a renowned clinical research organization in Canada.

The study results indicated a close to three fold increase in retention of cells within the heart muscle when using C-Cath. Within a clinical setting, an increased retention rate would allow the reduction of the administered dose while increasing the potency of the product, thereby increasing efficacy and reducing side effects. The cost of therapy could also be reduced through lower required doses. C-Cath's performance is based on its unique needle design which aims at increasing patient's safety, improving penetration and retention in the target tissue and enhancing fluid dynamics.

Dr Christian Homsy, CEO of Cardio3 BioSciences said: "While the key focus for Cardio3 BioSciences remains our unique stem cell treatment for heart failure, C-Cure, which is in clinical trials, today's announcement marks an important new step for the company towards its broader goal of becoming a leader in regenerative therapies for the treatment of heart diseases."

This latest study builds on earlier research showing C-Cath improves the retention of microparticles and a range of cell types at the injection site and is the final stage in pre-clinical development of the product. Cardio3 BioSciences will now further develop the C-Cath technology and advance the product towards regulatory approval as a Medical Device in Europe (CE Mark). Ultimately, C-Cath would potentially be used with C-Cure, an autologous stem cell-based therapy developed to help heal damaged heart tissue, and further Cardio3 BioSciences products in development such as allogeneic and protein therapeutics. C-Cath would also present an attractive delivery technology for a range of therapies in the cardiovascular and potentially other fields.

C-Cath was developed by Cardio3 BioSciences scientists and their clinical partners at the Cardiovascular Center in Aalst, Belgium. The work was supported by grants from the Walloon Region (DG06).

About Cardio3 BioSciences

Cardio3 BioSciences is a leading Belgian biotechnology company specialising in stem cell-based therapies for the treatment of cardiovascular disease. The Company's lead product, C-Cure(R), is a highly innovative approach to the treatment of heart failure, one of the world's most pressing unmet medical needs. Based on a strategy developed by Cardio3 BioSciences' founders and leveraging technology licensed from Mayo Clinic, C-Cure allows the differentiation of a patient's own cells into cardiopoeitic cells which grow into new heart cells and repair heart muscle.

The Cardio3 BioSciences team has extensive experience in developing and commercialising new pharmaceutical products and medical technologies and the Company's strategy is to drive the clinical development of C-Cure and to market the product itself in major territories.

Cardio3 BioSciences was founded in July 2007 and is based in Mont-Saint-Guibert in the Walloon region of Belgium.


Mayo Clinic holds equity in Cardio3 BioSciences as a result of intellectual property licensed to the company.

    For more information contact:

    Cardio3 BioSciences
    Dr Christian Homsy, CEO
    Tel: +32-10-39-41-00

    Anne Portzenheim,
    Communication Manager
    Tel : +32-10-39-41-00

    Citigate Dewe Rogerson
    Chris Gardner/Nina Enegren
    Tel : +44(0)207-638-9571

SOURCE Cardio3 BioSciences

Back to top
SOURCE Cardio3 BioSciences
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Cardio3 BioSciences Raises EUR13.7 Million in Series B Fundraising and Grant Funding
2. Harbor BioSciences to Receive Patent for Apoptone(R) Cancer Treatment
3. BD Biosciences Launches BD FACSAria(TM) III Flow Cytometry System
4. Hollis-Eden Announces Name Change to Harbor BioSciences, Inc. and Ticker Symbol Change to HRBR
5. Sangamo BioSciences Announces Fourth Quarter and Full Year 2009 Conference Call and Webcast
6. Ambit Biosciences and Astellas Enter Strategic Partnership to Research, Develop and Commercialize FLT3 Kinase Inhibitors in Multiple Indications
7. Sangamo BioSciences Announces Presentation of Preliminary Data From Phase 2 Study of SB-509 at International ALS Symposium
8. Ambit Biosciences Corporation Presents Phase I Clinical Results of AC220 in Patients With Acute Myeloid Leukemia at ASH Conference
9. CeloNova BioSciences CEO Urges More Heart, More Passion, More Honesty, and All Urgency in Developing Medical Devices
10. Regado Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference on December 1, 2009
11. Ambit Biosciences Corporation Announces Presentations Profiling AC220 Clinical and Non-Clinical Data at 51st American Society of Hematology Annual Meeting
Post Your Comments:
(Date:12/1/2015)... MARIETTA, Ga. , Dec. 1, 2015 ... purchase Dallas, Texas -based Tenet Healthcare,s ... WellStar Board of Trustees approved the strategic move following ... expand upon its proven clinical care models and patient ... improved access to healthcare to new communities. ...
(Date:12/1/2015)...  Eyeon Therapeutics has received a Notice of ... on a charged hydrophilic polymer developed at Particles ... has been shown to be safe and effective ... Mitchnick , MD, CEO states, "This second set ... in conjunction with a therapeutic agent.  Nanoparticles coated ...
(Date:12/1/2015)... Pharma Tech Outlook recently conducted a comprehensive ... Management Solution Providers - 2015 .  After careful consideration ... CIOs, VCs, analysts, and the Pharma Tech Outlook editorial ... 10 clinical data management solution providers (check out the ... 36 respectively). --> ...
Breaking Medicine Technology:
(Date:12/1/2015)... ... December 01, 2015 , ... Visage accelerates mobile ... wholly owned subsidiary of Pro Medicus Ltd. (ASX: PME), has announced they are ... of North America (RSNA) 2015 annual meeting through December 3 in Chicago, Illinois, ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... that it has been selected as a finalist in this year’s Fierce Innovation ... FierceMobileHealthcare. Next IT Healthcare was recognized as a finalist in the category of ...
(Date:12/1/2015)... MA (PRWEB) , ... December 01, 2015 , ... Lutronic, ... release of Clarity, the latest addition to the devices for sale in the United ... 755 nm Alexandrite and long-pulsed 1064 nm Nd:YAG lasers, into a single platform that ...
(Date:12/1/2015)... ... December 01, 2015 , ... PYA’s latest ... Integration ,” addresses a main “pain point” for merging or aligning healthcare provider ... a deal is signed. This quick-read guidance suggests that failing to recognize ...
(Date:12/1/2015)... ... December 01, 2015 , ... PartnerTech , ... membership and leadership since 2008. Gary Bruce, President of PartnerTech North America, currently ... spent a significant amount of time in Sweden since joining PartnerTech based in ...
Breaking Medicine News(10 mins):