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Cardio3 BioSciences Announces Positive Outcome of the C-Cure(R) Phase II Clinical Trial in Heart Failure Patients
Date:11/17/2010

he only difference between the two groups was the administration of C-Cure in the treatment group. C-Cure could ultimately represent a major step in advancing cardiac regenerative medicine, potentially offering a revolutionary treatment in patients suffering from heart failure, a devastating disease."

Prof. Andre Terzic, lead regenerative medicine specialist at Mayo Clinic in Rochester (MN), USA and Co-Principal Investigator of the C-Cure Clinical Trial commented: "Use of stem cells to seek to promote tissue repair in diseased hearts has the potential to transform medicine by providing curative solutions for the unmet needs of our patients. The C-Cure multicenter trial, which involved integrated teams on two continents, has introduced in the clinic the newest innovation under development in the field - namely the application of heart-prespecified stem cells in the treatment of heart failure. By translating a smart stem cell technology, known as "guided cardiopoiesis", into a first-in-class regenerative product candidate designed to be tailored to the individual patient, this study provides a critical step in our understanding of the feasibility, safety and efficacy of next generation cardiovascular medicine."

Using the insights from the trial and input from regulatory agencies in Europe and the United States, Cardio3 BioSciences is now designing a clinical trial programme for C-Cure expected to start in 2011.

About Cardio3 BioSciences

Cardio3 BioSciences is a leading Belgian biotechnology company focused on the discovery and development of regenerative and protective therapies for the treatment of cardiovascular disease.

The Company's lead product candidate, C-Cure(R), is a highly innovative stem cell approach for the treatment of heart failure, one of the world's most pressing unmet medical needs. Based on a comprehensive strategy developed by Cardio3 BioSciences and leveraging technology licensed from Mayo Clinic, the C-Cure
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SOURCE Cardio3 BioSciences
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