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Cardio3 BioSciences Announces Positive Outcome of the C-Cure(R) Phase II Clinical Trial in Heart Failure Patients
Date:11/17/2010

development programme is designed to direct the patient's own stem cells into new heart cells with the potential to rebuild the heart.

The Cardio3 BioSciences team has extensive experience in developing and commercialising new pharmaceutical products and medical technologies and the Company's current strategy is to drive the clinical development of C-Cure and to market the product itself, if marketing authorisation is obtained, on a wide geographical scale.

Cardio3 BioSciences was founded in July 2007 and is based in Mont-Saint-Guibert (near Louvain-la-Neuve) in the Walloon region of Belgium.

About C-Cure and Heart Failure

Heart failure is a life-threatening and increasingly common condition in which the heart cannot pump enough blood through the body, leaving the patient debilitated and significantly decreasing quality of life. It can result from heart attacks or a number of other causes. Patients suffering from the condition can experience shortness of breath and extreme exhaustion. Based on available data, the company estimates that 84 million people suffer from heart failure and that this number will double by 2020. Therapies available for chronic heart failure aim at slowing disease progression, but with the exception of heart transplant, existing drugs or devices do not cure the underlying disease.

C-Cure is produced by taking a patient's own stem cells and, through a proprietary process, differentiating them into cardiac lineage ("cardiopoietic") cells designed to regenerate damaged heart muscle. Cardiopoietic cells are injected into the heart of the patient with heart failure where they aim to replace damaged tissue and promote repair without carrying the risk of rejection. This is the first product candidate of its kind offering the potential for heart muscle regeneration. C-Cure is being developed on the basis of multiple years of research conducted at Mayo Clinic (Rochester, Minnesota, USA) and clinical expertise g
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SOURCE Cardio3 BioSciences
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