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Cardiac Dimensions® Announces Publication of TITAN Clinical Trial Data in European Journal of Heart Failure
Date:5/21/2012

entricular dilation among the comparison group.
  • Marked improvement in functional capacity was observed among implanted patients through 24 months with six-minute walk distances increasing by 131.9 plus or minus 80 meters (p<0.001).
  • A 30-day major adverse event rate of 1.9 percent was demonstrated on an intent-to-treat basis.
  • "From Cardiac Dimensions' inception, we have been focused on delivering a therapeutic modality that effectively addresses FMR via a safe and efficient percutaneous approach," stated David Reuter, M.D., Ph.D., Chief Medical Officer. "With the publication of the TITAN results, we now have substantial evidence that we have achieved this objective. Patients who suffer from FMR are a large and growing population with few viable options for treatment. This manuscript serves as a major step forward in establishing CARILLON as an important therapy, specifically targeted at this debilitating condition. The strength of the data reflects the clinical evolution of the technology and we are pleased to have partnered with some of the leading investigators in the field in achieving these results. As an organization, these data provide us with significant confidence as we initiate commercialization in Europe."

    About CARILLON® Mitral Contour System® Cardiac Dimensions' CARILLON Mitral Contour System combines a proprietary, implantable device with a percutaneous catheter delivery system. The implantable device consists of a proximal anchor and a distal anchor connected by a shaping ribbon. Utilizing the heart's natural structures, the device is intended to reduce mitral annulus dilatation upon deployment, thereby significantly reducing functional mitral regurgitation (FMR). Rapidly delivered via the venous vasculature, CARILLON has the potential to treat most heart failure patients in a minimally invasive fashion. Clinical data suggests that usage is associated with significant reduction in FMR, and s
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    SOURCE Cardiac Dimensions, Inc.
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