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Cannabis Science announces preclinical development program for CS-TATI-I, commencing EU operations in the Netherlands and sourcing proprietary material for pharmacokinetic characterization
Date:4/26/2013

he growth of and induces programmed cell death in KSHV in endothelial cells (Maor 2012).  Studies published in 2011 and 2012 in the Journal of Neuroimmune Pharmacology, PLoS ONE, and Journal of Pharmacology and Experimental Therapeutics found that cannabinoids inhibit macrophage migration to HIV TAT. 

A meeting by the Cannabis Science Scientific Advisory Board planned for May to be held immediately prior to the Institut Pasteur HIV meeting from May 21-23, 2013 in Paris, France, will examine the results of these initial studies for dissemination to leading publically sponsored clinical research programs to guide the design of Phase I studies.

About Kaposi's Sarcoma (KS)
KS is a form of cancer that develops typically from exposure to the HHV8 virus, a type of Herpes simplex virus. HHV8 can lay dormant in the body and develop when and if the immune system is dramatically weakened. KS arises from the cells that line lymph or blood vessels. KS lesions can occur internally in lymph nodes and visceral organs, externally on various parts of the body or both internally and externally.  There are distinct types of KS: epidemic HIV-associated KS and endemic KS.

About CS-TATI-1
Cannabis Science's research of CS-TATI-I will be targeted to newly diagnosed patients infected with drug resistant virus, treatment-experienced patients with drug-resistant HIV strains, and those intolerant of currently available therapies. Cannabis Science will be pursuing a wide range of Federal Research Programs such as RO1s, PO1s and SBIRs, which exist to support preclinical development of target validation and proof of concept studies. These studies will be implemented through collaborations with leading scientific institutions. Cannabis Science will also be pursuing other clinical research collaborations including the AIDS Clinical Trials Groups (ACTG), the Canadian AIDS Trial Network (CATN) and the European AIDS Trial Network (
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