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Cannabis Science Issues Guidance on Its Progress Toward FDA Investigative New Drug Applications For Clinical Trials and Proposed Dividend Payout for Current Shareholders to Receive a New Class of Common Stock
Date:10/12/2010

he application research we have been engaged in."

The following is a prioritized list of potential FDA Investigative New Drug Indications that Cannabis Science is researching:

Pain Management – Cannabis use in pain management has long been documented clinically and anecdotally.  A recent Canadian Medical Association publication showed "Our results support the claim that smoked cannabis reduces pain, improves mood and helps sleep"(Ware et al 2010).

The medical cannabis dispensary model has provided a wealth of observational data, with pain patients reporting improved pain management as well as increases in overall quality of life after beginning cannabis therapy.  Cannabis Science licensee RockBrook, Inc. works with one of the leading pain management doctors in the State of Colorado, which has led to the selection of a standardized cannabis strain and appropriate methods of ingestion for these patients. This strain and its formulated products will be available for dispensary sale in the next quarter.  Because pain management is often associated with Post Traumatic Stress Disorder (PTSD, see below), it is likely that both indications will be targeted with this same formulation in the new drug application.

Last year, MarketResearch.com reported that the "global pain management market generated $46.4 billion sales in 2007, a 12.5% increase over 2006. The most prevalent forms of neuropathic pain in the seven major markets were neuralgia/fibromyalgia and lower back pain, with 16.3m and 15.9m cases respectively during 2008."

See http://www.marketresearch.com/product/display.asp?productid=2290433

Post Traumatic Stress Disorder (PTSD) – Recent peer-reviewed literature, as well as practical applications in foreign markets such as Israel, show that medical cannabis can be extremely effective in the clinical treatment of PTSD and
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SOURCE Cannabis Science, Inc.
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