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Cancer Vaccines: From First-in-Class to Best-in-Class?
Date:4/9/2013

dditional Information 6
2.4 BioSeeker Group's Oncology Team 6
3 Methodology 7
3.1 Cancer Highlights' Five Pillar Drug Assessment 7
4 Table of Contents 9
4.1 List of Figures 19
4.2 List of Tables 19
5 Introduction 28
5.1 The Scope of this Report 28
5.2 Definitions 31
5.3 Abbreviations 31
6 Consider the Therapeutic Target Among Cancer Vaccine Drugs for the Highest Therapeutic Outcome and Return on Investment 32
6.1 Drug Repositioning in Oncology 32
6.2 Introduction to Targets of Cancer Vaccine Drugs 33
6.2.1 Acid Phosphatase Activity Targets 38
6.2.2 Carboxypeptidase Activity Targets 39
6.2.3 Catalytic Activity Targets 41
6.2.4 Cell Adhesion Molecule Activity Targets 43
6.2.5 Chaperone Activity Targets 52
6.2.6 Cofactor Binding Targets 54
6.2.7 Complement Activity Targets 56
6.2.8 Cytokine Activity Targets 58
6.2.9 DNA Binding Targets 68
6.2.10 DNA Topoisomerase Activity Targets 70
6.2.11 DNA-directed DNA Polymerase Activity Targets 71
6.2.12 Growth Factor Activity Targets 72
6.2.13 GTPase Activity Targets 79
6.2.14 Heat Shock Protein Activity Targets 81
6.2.15 Hormone Activity Targets 83
6.2.16 Isomerase Activity Targets 84
6.2.17 Kinase Binding Targets 85
6.2.18 Kinase Regulator Activity Targets 86
6.2.19 Metallopeptidase Activity Targets 88
6.2.20 MHC Class I Receptor Activity Targets 90
6.2.21 Molecular Function Unknown Targets 93
6.2.22 Oxidoreductase Activity Targets 112
6.2.23 Peptidase Activity Targets 114
6.2.24 Peptide Hormone Targets 123
6.2.25 Protein Binding Targets 126
6.2.26 Protein Serine/Threonine Kinase Activity Targets 128
6.2.27 Protein-tyrosine Kinase Activity Targets 130
6.2.28 Receptor Activity Targets 133
6.2.29 Receptor Binding Targets 147
6.2.30 Receptor Signaling Complex Scaffold Activity Targets 152
6.2.31 Receptor Signaling Protein Serine/Threonine Kinase Activity Ta
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