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Cancer Treatment Centers of America(R) Studies Treatment That Aims Chemotherapy Directly at Ovarian Cancer Cells
Date:6/17/2009

Therapy targets folate receptors found on cancer cells otherwise resistant to standard chemo

ZION, Ill., June 17 /PRNewswire-USNewswire/ -- Cancer Treatment Centers of America (CTCA) at Midwestern Regional Medical Center, a leading provider of innovative cancer care for patients living with complex and advanced-stage disease, is the only hospital in Illinois and Wisconsin to take part in new clinical research involving a treatment designed to target ovarian cancer cells otherwise resistant to standard chemotherapy.

(Logo: http://www.newscom.com/cgi-bin/prnh/20090612/CTCALOGO)

The Phase II clinical study, called "PRECEDENT," is designed to evaluate the safety and efficacy of EC145, a drug currently being studied in the treatment for women with ovarian cancer who develop a resistance to standard platinum-based chemotherapy. EC145 was developed by Endocyte, a privately-held biotechnology company.

"With EC145, we're working to target a powerful chemotherapy drug directly to cancer cells while sparing the healthy cells," says Dr. Sybilann Williams, MD, gynecologic oncologist and surgeon at Cancer Treatment Centers of America at Midwestern Regional Medical Center and principal investigator for the PRECEDENT study. "EC145 is designed to target the folate receptors found in high concentrations on cancer cells," she adds.

In order to be eligible for the PRECEDENT study, patients must have platinum-resistant ovarian cancer where the disease has progressed or recurred within six months of a first or second treatment with a platinum-based chemotherapy drug. Those elig
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SOURCE Cancer Treatment Centers of America
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