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Cancer Research UK Signs Deal With Centella Therapeutics, Inc. to Launch Clinical Development of Radiotherapy-Enhancing Drug
Date:5/25/2011

ncer patients. Two drugs from the CDP initiative are already in early phase trials.

CEN-209 is currently in pre-clinical development. Under the terms of the partnership, Cancer Research UK's Drug Development Office will complete pre-clinical development of the drug and take it through the first Phase I clinical trial, which will be conducted through the charity's Experimental Cancer Medicine Centres.

After the Phase I trial Centella will have the exclusive option to buy back the clinical trial data and conduct further clinical studies towards approval of CEN-209.  If Centella doesn't exercise its option, the rights to the programme will be transferred to Cancer Research Technology to secure an alternative partner with the goal of making it possible for the drug to reach cancer patients.  

Dr. Thorsten Melcher, president of Centella, said: "We are very pleased to work in this public-private partnership with the experts from Cancer Research UK to advance CEN-209. The drug development experience of Cancer Research UK is very well respected and critical to evaluate the potential of CEN-209 for attacking hypoxic tumours for which few effective treatments are available today. Centella is particularly excited to launch this important project that may make radiotherapy even more effective, and to do it in the year that the United Kingdom has dedicated to raising awareness for radiotherapy."

2011 was designated "The Year of Radiotherapy" in the UK, to help raise awareness of the treatment and highlight the progress made over the last century.

Dr. Ian Walker, senior licensing manager at Cancer Research UK's Drug Development Office, said: "Through this exciting partnership, we are taking a completely new drug which could treat a range of cancer types into clinical trials - bringing new hope for thousands o
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SOURCE Varian Medical Systems
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