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Cancer Experts Detail New Approaches to Liver Cancer Treatment with Stereotactic Ablative Radiotherapy
Date:9/3/2013

op="name">Carlo Greco, MD, professor and director of clinical research at the Champalimaud Foundation in Lisbon, Portugal, discussed advances in imaging and biological targeting that enable high precision single-dose image-guided radiotherapy (SD-IGRT) for treating metastatic lesions in the liver as well as elsewhere in the body.  "These treatments depend on our ability to accurately position patients for treatment, use imaging for precise targeting, and manage motion during treatment," said Dr. Greco. 

The TrueBeam™ platform from Varian Medical Systems (NYSE: VAR), with its high dose delivery rate, enables fast completion of these otherwise time-consuming treatments.  "Since we installed the TrueBeam machine in early 2012, we have treated over 400 metastatic lesions with high dose SD-IGRT," Dr. Greco said.  "Lung, bone, liver, adrenal gland and lymph node lesions have been the focus of our experience. Based on follow-up imaging studies, we're seeing outstanding early local control rates, with 95% of lesions free of relapse at twelve months following treatment."

Encouraging Outcomes Reported From Milan
Marta Scorsetti, M.D., director of the Department of Radiation Oncology and Radiosurgery at the Humanitas Cancer Center in Milan, Italy, presented her work evaluating the feasibility and efficacy of SABR in the treatment of both inoperable primary liver cancer and liver metastases.  She reported on the results obtained with 67 patients treated for metastatic lesions, and 18 patients with primary HCC lesions.

While specific local tumor control and overall survival results varied, after a median follow-up of 12 months all groups showed acceptable rates of local tumor control and very little treatment related toxicity.  No radiation induced liver disease (RILD) was detected
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SOURCE Varian Medical Systems, Inc.
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