Navigation Links
Can Hormone Help Treat Multiple Sclerosis Long-Term?
Date:3/10/2013

SAN DIEGO, March 10, 2013 /PRNewswire-USNewswire/ -- A new study suggests that treatment with adrenocorticotropic hormone (ACTH) may be helpful for people whose multiple sclerosis (MS) is not well-controlled through their regular treatment. The study was released today and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

The study involved 23 people with MS who were taking beta-interferon treatment and had at least one relapse or brain scan showing new disease activity within the previous year. They were considered to have "breakthrough" MS, which means that their treatment that had been working previously stopped being effective, leading to worsening disability and more frequent relapses, as well as increased evidence of disease activity on brain scans.

The study participants were given either ACTH or methylprednisolone as pulse therapy monthly in addition to their regular treatment for one year. The people with MS knew which treatment they were receiving, but the researchers examining them did not.

The participants were tested every three months for 15 months. Over that time, those receiving ACTH had fewer relapses, or 0.08 cumulative relapses per patient compared to 0.8 relapses per patient for those receiving methylprednisolone. Those taking ACTH also had no cases of psychiatric side effects, while those taking methylprednisolone had a cumulative number of 0.55 psychiatric episodes per patient.

"These results are of interest because few treatments are available for people with breakthrough MS," said study author Regina Berkovich , MD, PhD, of Keck Medical Center of USC in Los Angeles. "Further studies, including randomized controlled trials, are needed to validate these preliminary findings, but the results suggest a potential benefit of ACTH pulse therapy in breakthrough MS."

While ACTH has been approved for use in MS relapses for many years, its cost has limited its use to only those patients who are in need of a relapse treatment alternative to corticosteroids. This is believed to be the first study to have been done on its use as a chronic treatment for MS. ACTH is not FDA-approved for use as chronic treatment for MS.

The study was supported by a research grant from Questcor Pharmaceuticals, Inc., maker of ACTH.

Learn more about multiple sclerosis at http://www.aan.com/patients.

The American Academy of Neurology, an association of more than 25,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, brain injury, Parkinson's disease and epilepsy.

For more information about the American Academy of Neurology, visit http://www.aan.com or find us on Facebook, Twitter, Google+ and YouTube.


'/>"/>
SOURCE American Academy of Neurology
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Product Differentiation to Boost European Human Growth Hormones Market, Says Frost & Sullivan
2. Transdermal Hormone Replacement: Products, Players, Markets and Forecasts
3. Endocrinology Market to 2018 - Advanced Injection Devices for Growth Hormone and Somatostatin will Improve Ease of Use for Patients
4. Early Detection of MS Treatment Complication May Improve Survival
5. Abattis Participates In Project On A Whole Plant Therapeutic For Treating Malaria And Other Diseases And Reducing Drug Resistance
6. Study: Surefire Medicals Technology Improves Delivery Of Embolics In Cancer Treatment
7. 95% Cure Rate for Prostate Cancer In Men Treated With HIFU (High Intensity Focused Ultrasound)
8. Boehringer Ingelheim Announces Interim Results Evaluating Virologic Response Rates in HCV/HIV Co-Infected Patients Treated with Faldaprevir
9. NeuroDerm Announces Positive Results of a Phase I Study of ND0612 for the Treatment of Parkinsons Disease
10. Bloomberg BNA Publishes Sixth Edition of False Claims Act Treatise
11. Studies Published in Pain Medicine Demonstrate Effectiveness of Minimally-Invasive Cooled Radiofrequency Treatment for Low Back Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2016)... May 20, 2016 The Biotech ... believe that the industry is not far from recovering. ... ActiveWallSt.com featured the following four equities: Anacor Pharmaceuticals Inc. ... ATHX ), Aralez Pharmaceuticals Inc. (NASDAQ: ... INFI ). Sign up for your free trading alerts ...
(Date:5/20/2016)... According to the 2016 home healthcare market report, ... healthcare solutions as since the early 2000s, the cost of ... the US, the healthcare cost rose faster than inflation during ... inflation rate stood at an average of 2.04% during 2005-2015, ... the same time period. This can be attributed to the ...
(Date:5/19/2016)... May 19, 2016  According to the World ... world lacks basic diagnostic imaging. Whereas mammography or ... the United States , many places around ... In fact, the WHO reports that those approximately ... or treatable death, simply due to the unavailability ...
Breaking Medicine Technology:
(Date:5/24/2016)... Loma Linda, CA (PRWEB) , ... May 24, 2016 , ... ... that will house the new adult hospital and expanded Children’s Hospital. Over 3,000 people ... May 22. , Check out the event photo slidehsow. , During the ...
(Date:5/24/2016)... Angeles, CA (PRWEB) , ... May 24, 2016 ... ... to everything egg freezing, today announced the official relaunch of its community and ... use their frozen eggs. Eggsurance's mission is to create a safe and welcoming ...
(Date:5/24/2016)... ... ... Tuesday, May 24, Women's Excellence in Wellness, powered by Movestrong will be ... taught by Patti Dolan, RYT, a Young Living Gold Member. The class is ... 7:15pm followed by a small intro to the Oils that can benefit the student's ...
(Date:5/24/2016)... ... ... In light of recent heavy flooding in Houston, Texas, Pelican Water Systems is ... Houston area. , Heavy floodwaters have led to destroyed waterways and flooded reservoirs. The ... even be aware of the contamination of their water supply and thus, may be ...
(Date:5/24/2016)... ... May 24, 2016 , ... "ProText Layouts Vol. 3 ... Austin - CEO of Pixel Film Studios. , ProText Layouts Vol. 3 is a ... Cut Pro X . With ProText Layouts, video editors can create an lively typography ...
Breaking Medicine News(10 mins):