Navigation Links
Caliper Life Sciences Launches Novel COX-2 Probe to Enable Personalized Medicine Research
Date:4/4/2011

HOPKINTON, Mass., April 4, 2011 /PRNewswire/ -- Caliper Life Sciences, Inc. (NASDAQ: CALP), a leading provider of tools and services for drug discovery, life sciences research and molecular diagnostics, today announced the launch of XenoLight(TM) RediJect(TM) COX-2 Probe (Fluorocoxibs), a novel fluorescent imaging agent for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker noninvasively in live animal models as well as in ex vivo tissue analysis applications. The COX-2 fluorescent probe technology was invented at the research laboratory of Dr. Lawrence Marnett at Vanderbilt University and is licensed to Caliper.

"COX-2 is over-expressed in a variety of inflammatory and neoplastic diseases.  The opportunity to non-invasively image COX-2 offers promise for both the early detection of disease and monitoring therapeutic response.  The fluorocoxib probe should be valuable to investigators in multiple disciplines, including cancer research," said Professor Andrew Dannenberg, Director of Cancer Center at Weill Cornell Medical College, a research leader in the field of COX-2 in oncology and inflammation.

Researchers can gain an understanding of therapeutic efficacy in specific patient populations by monitoring key biomarker response to a drug treatment.  These findings then help tailor patient-specific therapeutic strategies to improve outcomes and advance the scope of personalized medicine.  For example, COX-2 detection in tumors has become an important tool in predicting the outcome of various chemotherapy treatments, including advanced lung cancer.  Caliper's RediJect COX-2 probe provides the ability to non-invasively detect COX-2 in early-stage cancer cells, with a level of sensitivity and accuracy not attainable by conventional methods.  

"Personalized therapies to treat specific patient populations are becoming reality," said Kevin Hrusovsky, President and CEO of Caliper Life Sciences. "Our partnership with Professor Lawrence Marnett, the inventor of the COX-2 probe and a prolific author and thought leader in the field, will further catalyze research in biomarker response, helping to provide insight into the development of new or rescued targeted therapies.  Caliper remains committed to providing translational research technology and services focused on further realizing the full potential of personalized medicine."

The RediJect COX-2 probe is the latest in an expanding range of reagents for Caliper's IVIS® and Maestro® optical imaging systems, and our Trio(TM), Nuance® and Vectra® tissue analysis systems. Caliper's portfolio of industry-leading pre-clinical imaging technology complements an expansive range of imaging reagents optimized to enable researchers to monitor various biological events, in live models and in excised tissue samples.  Caliper offers a variety of fluorescent and bioluminescent reagents that can be applied in a range of therapeutic areas, including oncology, infectious diseases, inflammation, neurology and stem cell research.

About Caliper Life Sciences

Caliper Life Sciences is a premier provider of cutting-edge technologies enabling researchers in the life sciences industry to develop life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper is aggressively innovating new technology to bridge the gap between in vitro assays and in vivo results that translate into potential cures for a range of diseases. Caliper's portfolio of offerings includes state-of-the-art microfluidics, lab automation & liquid handling, optical imaging technologies, and discovery & development outsourcing solutions. For more information please visit www.caliperLS.com.

Caliper and IVIS are registered trademarks, and XenoLight and RediJect are trademarks, of Caliper Life Sciences, Inc.  Maestro, Nuance and Vectra are registered trademarks, and Trio is a trademark, of Cambridge Research and Instruments, Inc., a wholly owned subsidiary of Caliper Life Sciences, Inc.


'/>"/>
SOURCE Caliper Life Sciences, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Caliper Life Sciences Introduces Drug Combination Services to Identify Synergistic Response of Compounds
2. Caliper Life Sciences Optical Imaging Technology Selected to Aid Tuberculosis Research Efforts by the Texas A&M Health Science Center
3. Caliper Life Sciences Presents LabChip(R) Platform to the U.S. Food and Drug Administration
4. Caliper Awarded New Task Order for EPA ToxCast Program
5. Caliper Life Sciences Introduces Sciclone(R) G3 Liquid Handler
6. Caliper Life Sciences Partners with Prestwick Chemical to Offer Customized Chemistry and Biology Programs for Drug Discovery Research
7. Caliper Completes Strategic Sale of Small Animal Services Subsidiary to Taconic
8. Caliper Life Sciences Forms Scientific Advisory Board for Next Generation Sequencing
9. Caliper Life Sciences Fourth Quarter 2009 Financial Results Conference Call Notice
10. Caliper Life Sciences and Stanford University File a Patent Infringement Lawsuit Against Carestream Health, Inc.
11. Caliper Settles Outstanding Litigation with Shimadzu
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2017)... After the recent election cycle, it is clear ... for medical and recreational purposes are shifting. The evidence shows ... of cannabis, but the focus is coming from both the ... North American legal cannabis market posted $6.7 billion in revenue ... projects sales will grow at a compound annual growth rate ...
(Date:1/17/2017)... , Jan. 17, 2017 Precision medicine ... for the treatment of disease. The approach allows ... to a therapy. The approach studies the individual ... lifestyle and environment. In January 2015, Precision Medicine ... to all diseases with more than one million ...
(Date:1/17/2017)... , Jan. 17, 2017 EU5 Glucose Monitoring ... new report, "EU5 Glucose Monitoring Market Outlook to 2022", ... market. The report provides value, in millions of US ... market segments - Blood Glucose Meters, Blood Glucose Test ... shares and distribution shares data for each of these ...
Breaking Medicine Technology:
(Date:1/18/2017)... Silver Spring, MD (PRWEB) , ... January 18, 2017 , ... ... and financial consultations to families and business owners in central Maryland and the DC ... community. , Heart disease kills 787,000 people nationally every year, making it the #1 ...
(Date:1/18/2017)... N.J. (PRWEB) , ... January 18, 2017 , ... ... delivery technologies and development solutions for drugs, biologics and consumer health products, today ... will be presenting at the upcoming WCBP Conference, to be held at the ...
(Date:1/18/2017)... Hills, CA (PRWEB) , ... January 18, 2017 ... ... of dental problems ranging from gum disease to enamel erosion, and those dental ... the Massachusetts Department of Public Health, many pregnant women are failing to get ...
(Date:1/17/2017)... ... January 17, 2017 , ... Gym Source, America’s leading retailer of ... at South Dixie Hwy in Miami, FL. , “We are elated to be opening ... innovative in-store concept is designed to give clients a seamless and motivating shopping experience.” ...
(Date:1/17/2017)... Phoenix, AZ (PRWEB) , ... January 17, 2017 ... ... new and improved supplement, Healthful-Flex. , The company, owned and operated by ... the public at a reasonable price with the highest level of customer service. ...
Breaking Medicine News(10 mins):