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Caliber and ImmunGene Launch Valor Biotherapeutics, a Joint Venture to Develop Antibody-Interferon Fusion Therapeutics to Treat Cancers
Date:11/13/2012

THOUSAND OAKS, Calif. and BRYAN, Texas, November 13, 2012 /PRNewswire-iReach/ -- ImmunGene, Inc. (ImmunGene) and Caliber Biotherapeutics, LLC (Caliber) announced today the launch of Valor Biotherapeutics, LLC (Valor), a joint venture focused on the clinical development and commercialization of monoclonal antibody-interferon (mAb-IFN) fusion protein therapeutics targeting certain cancers.  The mAb-IFN fusion protein technology was invented in Professor Sherie Morrison's laboratory at the University of California, Los Angeles and licensed exclusively to ImmunGene.  This technology is being used to enable the precise targeting of tumor cells with monoclonal antibodies and their destruction by interferon.

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Valor will combine the assets and resources of Caliber with ImmunGene's technologies, know-how, and intellectual property (IP).   ImmunGene will grant Valor exclusive licenses to its IP for three mAb-IFN fusion product candidates currently in various stages of preclinical development. Caliber will commit sufficient funds to enable Valor to reach certain development milestones for these compounds in the treatment of non-Hodgkin's lymphoma, multiple myeloma, and breast cancer.

Valor will be led by Rahul Singhvi, Sc.D., Managing Director of Caliber Biotherapeutics, LLC and former President and CEO of Novavax, Inc. Dr. Singhvi will be joined on the Valor board of directors by David Shanahan, a serial entrepreneur, philanthropist and a Caliber founder.  Mr. Shanahan is also the founder and President of Gradalis, Inc., a cancer immunotherapy company, and President of the Mary Crowley Cancer Research Center.  Dr. Sanjay Khare, CEO of ImmunGene, and Dr. Michael Gresser, Chair of ImmunGene's scientific advisory board, will also join the Valor board.

Dr. Singhvi commented, "The creation of
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SOURCE Valor Biotherapeutics
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