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Cadence Pharmaceuticals Reports Fourth Quarter and Full Year 2010 Financial Results
Date:3/3/2011

so believe that this promising start, along with the proceeds from last year's public offering, have positioned us for a successful 2011."

GuidanceCadence currently estimates that OFIRMEV will be on formulary at approximately 800 to 1,000 hospitals by December 31, 2011. Cadence believes that this penetration would represent approximately half of the total U.S. IV analgesic market opportunity for OFIRMEV.

Conference Call and Webcast on March 4, 2011 at 5:30 a.m. Pacific Time (8:30 a.m. Eastern Time)Cadence management will host a conference call on March 4, 2011 at 5:30 a.m. Pacific Time (8:30 a.m. Eastern Time) and interested investors may participate in the conference call by dialing (877) 303-9145 (domestic) or (760) 536-5203 (international). To access the webcast, please visit the company's website at www.cadencepharm.com and go to the Investor Relations page. A replay of the webcast will be available approximately two hours after the call and remain available on the company's website until the next quarterly financial results call.

About OFIRMEV™ (Acetaminophen) InjectionOFIRMEV (acetaminophen) injection, Cadence Pharmaceuticals' proprietary intravenous formulation of acetaminophen, is indicated for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics and reduction of fever. The FDA approval of OFIRMEV was based on data from clinical trials in which a total of 1,020 adult and 355 pediatric patients received IV acetaminophen. These trials included two studies evaluating the safety and effectiveness of OFIRMEV in the treatment of pain, and one study evaluating OFIRMEV in the treatment of fever.

Important Safety InformationDo not exceed the maximum recommended daily dose of acetaminophen. Administration of acetaminophen by any route in doses higher than recommended may result in hepatic injury, including the
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SOURCE Cadence Pharmaceuticals, Inc.
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