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CVS Caremark Research Finds New, More Accurate Method for Classifying Patient Medication Adherence Behaviors
Date:9/12/2013

WOONSOCKET, R.I., Sept. 12, 2013 /PRNewswire/ -- Researchers at CVS Caremark (NYSE: CVS) and Brigham and Women's Hospital have found that a new approach to classifying patients by their long-term medication adherence behavior may be more accurate than traditional approaches. In a study published in the September 2013 issue of Medical Care, the researchers followed more than 264,000 statin-users over a 15-month period and created measures to account for different adherence behaviors. The researchers identified key groups into which various patients would fall based on these measures in an effort to predict and compare their long-term adherence patterns.

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The study utilized a new method of categorizing adherence called group-based trajectory modeling, which is based upon observed patterns of medication-filling over time.  This method allows researchers to more accurately capture and describe adherence compared to techniques that simply classify patients as adherent or not, using average levels of adherence.  In addition, the trajectory patterns that are created should allow for more targeted interventions to address non-adherence.  In this study, use of trajectory modeling was especially useful for accounting for variable patterns of intermittent and long-term adherence behaviors.

"Our findings could help facilitate research on medication adherence and medication effectiveness in a variety of ways," said Niteesh Choudhry, MD, PhD, associate physician, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and associate professor, Harvard Medical School. "For example, by using group-based trajectory modeling, we could help identify patients with distinct
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SOURCE CVS Caremark Pharmacy Services
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