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CVS Caremark Research Finds Medication Adherence Can Improve Outcomes and Reduce Costs for Patients with Coronary Artery Disease
Date:3/19/2013

on the relationship between medication adherence and costs and outcomes related to secondary prevention of the disease. All of the studies reviewed found that adherence significantly improves health outcomes, and those that analyzed costs found reduced total annual CAD costs (consistently between $294 and $868 per patient).

While the study found consistent outcomes in cost reductions and health improvements related to better medication adherence, the researchers also identified an opportunity for greater standardization and improved research methods across medication adherence studies. The authors pointed out that many of the studies they reviewed did not account for what they refer to as the "healthy adherer" effect; noting that few of the studies they analyzed controlled for predisposed healthy behaviors in the patients that were followed.

"The research community has long believed that those patients who adhere to their medications may also be more likely to pursue a healthier lifestyle," said Asaf Bitton , MD, MPH, lead author of the study affiliated with the Brigham and Women's Hospital Division of General Medicine and the Harvard Medical School Center for Primary Care. "The next step from a research perspective would be to find a consistent way to control for the effect of these 'healthy adherers' to provide a more accurate picture of adherence for future studies and to further advance the research science in this field."

Heart disease is the leading cause of death in the United States for both men and women. About 600,000 people die of heart disease in the United States every year with coronary heart disease being the most common type of heart disease, killing more than 385,000 people annually.[1]

CVS Caremark has been working in a multi-year collaboration with Harvard University and Brigham and Women's Hospital to research pharm
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