Navigation Links
CRESTOR Demonstrates Dramatic CV Risk Reduction in a Large Statin Outcomes Study
Date:11/9/2008

ed, AstraZeneca (NYSE: AZN) expects to file a regulatory submission including the JUPITER data in the first half of 2009 and if approved, will begin promotional activities within the approved labeling.

Rosuvastatin is not indicated for the prevention of cardiovascular events. Rosuvastatin should be used according to the prescribing information, which contains recommendations for initiating and titrating therapy according to the individual patient profile. In most countries, the usual recommended starting dose of rosuvastatin is 10 mg.

Rosuvastatin 20 mg was well tolerated in nearly 9,000 patients during the course of the study. There was no difference between treatment groups for major adverse events, including cancer or myopathy. There was a small increase in physician reported diabetes consistent with data from other large placebo controlled statin trials.

ABOUT JUPITER:

JUPITER (Justification for the Use of statins in Primary prevention: an Intervention Trial Evaluating Rosuvastatin) was a long-term, randomized, double-blind, placebo-controlled, large-scale study of 17,802 patients designed to determine if rosuvastatin 20 mg decreases the risk of heart attack, stroke and other major cardiovascular events in patients with low to normal LDL-C but at increased cardiovascular risk as identified by elevated high-sensitivity C-reactive protein (hsCRP) and age. The majority of patients had at least one other risk factor including hypertension, low HDL-C, family history of premature coronary heart disease (CHD) or smoking. hsCRP is a recognized marker of inflammation which is associated with an increased risk of atherosclerotic cardiovascular events.

JUPITER is a part of AstraZeneca's extensive GALAXY clinical trials
'/>"/>

SOURCE AstraZeneca
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Abbott and AstraZeneca Announce Selection of Next-Generation Fenofibrate ABT-335 and CRESTOR(R) Fixed-Dose Combination
2. New Analysis of METEOR Study Demonstrate Effects of AstraZenecas CRESTOR(R) (Rosuvastatin Calcium) on Atherosclerosis in Patients With Two or More Risk Factors for Cardiovascular Disease
3. Phase III Study of Abbotts Investigational TriLipix(TM) in Combination With AstraZenecas CRESTOR(R) Meets Primary Endpoints on Key Lipids
4. Abbotts Phase III Sub-Group Analysis Shows Investigational TriLipix(TM) in Combination with CRESTOR(R) Improves Key Lipids in Patients with Mixed Dyslipidemia and Type 2 Diabetes
5. Cytokine Demonstrates Oral Efficacy of Small-Molecule MIF Inhibitors
6. Lpath Demonstrates Strong Safety Profile of Lead Drug Candidate, Sphingomab(TM), in Non-Human Primates
7. ImmuneRegen BioSciences, Inc. Demonstrates Radilex(TM) Increases Disease-Fighting White Blood Cells
8. New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia
9. Cypher(R) Sirolimus-Eluting Coronary Stent Demonstrates Sustained Clinical Benefits Compared to Bare Metal Stents in Five-Year Randomized Clinical Trial With No Differences in Long-Term Safety
10. Lpath Demonstrates Preclinical Efficacy of Lpathomab(TM) and Initiates Humanization Process
11. R7128 Demonstrates Safety and Potent Antiviral Activity in HCV-Infected Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)...  In an unprecedented effort to curb the spread of "superbugs" such ... vehicles, an advanced and portable UV germicidal lamp manufactured by MRSA-UV ... In order to prevent EMS paramedics and transport ... West Palm Beach Fire Rescue is the first in ...
(Date:1/15/2014)... MultiCell Technologies, Inc. (OTC Bulletin Board: MCET.OB ... composition of matter, biological targets, mechanism of action, methods ... This patent application describes a novel class ... which interfere with the basic homeostatic cellular processes in ...
(Date:1/15/2014)... , Jan. 15, 2014 The Cadence Fitness & ... Center by the Medical Fitness Association, a non-profit organization ... their full potential. The Cadence Fitness & Health Center ... suburbs and second in the Chicagoland area. ...
Breaking Medicine Technology:Superbugs No Longer Ride In Rescue Vehicles 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
(Date:7/9/2014)... research into the metabolism of stromal support cells and ... of these cell types in the development of diseases ... conditions and cancer. That was the conclusion of a ... in the leading journal Nature . , Prof. ... wake-up call. The metabolism of cancer cells has been ...
(Date:7/9/2014)... found that fecal transplantation is effective and safe for ... is the result of a study led by Colleen ... Gastrointestinal Medicine at The Women,s Medicine Collaborative. The study ... of print in the American Journal of Gastroenterology ... diff , has increased to epidemic proportions over the ...
(Date:7/9/2014)... The Miriam Hospital have found that people with ... depressed have difficulty sticking to a pulmonary rehabilitation ... women, and screening and brief treatment of depression ... study and its findings are published in print ... obstructive pulmonary disease is a common and often ...
(Date:7/9/2014)... news release is available in French . ... factors in 14 year old teens, including brain structure and ... 70% accuracy who will go on to develop binge drinking ... of conscientiousness, and other variables such as life events and ... of binge drinking. Whether or not the child had ...
(Date:7/9/2014)... Researchers from Montefiore Medical Center and ... Yeshiva University will present new findings at the Alzheimer,s ... July 17 in Copenhagen, Denmark. Data from the four ... from cognitive normality to mild cognitive impairment and dementia. ... Study , established in 1980 to examine healthy brain ...
Breaking Medicine News(10 mins):Health News:Wake-up call for more research into cell metabolism 2Health News:Women's Medicine Collaborative examines safety of fecal transplant to treat C. difficile 2Health News:Miriam Hospital study examines effect of depressed mood on pulmonary rehab completion 2Health News:What drives a child to abuse alcohol? 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 3
... antidepressants, effectiveness , , THURSDAY, April 17 (HealthDay News) -- ... brain cells to their more plastic youthful condition in ... provides a possible new explanation for the antidepressant activity ... that it could be used to treat other conditions ...
... Funds Awarded to Reconstruct Devastating,Injuries;, Not all ... April 17 Members of,the American Society of ... the next five years developing groundbreaking therapies to ... Afghanistan. The U.S.,Department of Defense (DoD) has awarded ...
... Known Risks of Lead Paint in,Products Sourced in China, ... WASHINGTON, April 17 Based on a review of ... for 2006,and 2007, major industrial and other sectors affected ... informing shareholders of market risks they,face due to toxic ...
... 17 MSA (NYSE: MSA ), the,global leader ... protect people,s health and safety, announced today that it,will ... via the,Internet on Thursday, May 1, 2008 at 10:00 ... Investors and interested parties will have the opportunity to ...
... other diseases that affect red blood cells , , THURSDAY, April ... skin, says a new study that showed the skin plays ... and in stimulating kidney production of the hormone erythropoietin (EPO) ... blood cells that carry and deliver oxygen throughout the body. ...
... Nearly 20 percent of military service members who have ... -- report symptoms of post traumatic stress disorder or ... sought treatment, according to a new RAND Corporation study. ... returning service members report that they experienced a possible ...
Cached Medicine News:Health News:Prozac Makes Old Brain Cells Young 2Health News:Prozac Makes Old Brain Cells Young 3Health News:Plastic Surgeons Play Pivotal Role in War Injury Research 2Health News:Plastic Surgeons Play Pivotal Role in War Injury Research 3Health News:'Toxic Stock Syndrome' Report: Many Companies Are Keeping Shareholders in the Dark on Potential Recalls, Bans, and Other Risks 2Health News:'Toxic Stock Syndrome' Report: Many Companies Are Keeping Shareholders in the Dark on Potential Recalls, Bans, and Other Risks 3Health News:'Toxic Stock Syndrome' Report: Many Companies Are Keeping Shareholders in the Dark on Potential Recalls, Bans, and Other Risks 4Health News:'Toxic Stock Syndrome' Report: Many Companies Are Keeping Shareholders in the Dark on Potential Recalls, Bans, and Other Risks 5Health News:MSA Schedules First Quarter Earnings Webcast 2Health News:Mice Can Sense Oxygen Through Their Skin 2Health News:Study finds 1 in 5 Iraq and Afghanistan veterans suffer from PTSD or major depression 2Health News:Study finds 1 in 5 Iraq and Afghanistan veterans suffer from PTSD or major depression 3Health News:Study finds 1 in 5 Iraq and Afghanistan veterans suffer from PTSD or major depression 4Health News:Study finds 1 in 5 Iraq and Afghanistan veterans suffer from PTSD or major depression 5
... tilt, user programmable memory two position ... on both chair sides, solid cast ... Single button folding armrests and headrest, ... on both chair sides, ergonomically contoured ...
... chair for examination of the ... adjustable from 540 mm to ... an independent foot switch. The ... and incorporates a multi-adjustable headrest, ...
Heine Beta 200 Streak Retinoscope 3.5v w/Twist Lock for Welch-Allyn style handles....
Heine Beta 200 Streak Retinoscope 3.5v...
Medicine Products: