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COPD Tops Asthma as the Focus Indication for Next Generation Respiratory Therapies at the 2012 American Thoracic Society Conference
Date:5/31/2012

y in advance of the registration of the associated FDC product."

Despite the notable omission of pivotal RELOVAIR trial data from this year's ATS proceedings, GSK and Theravance continue to be the trailblazers in the race to launch the next generation COPD therapy through their partnership in two key FDC programs, RELOVAIR (fluticasone furoate+vilanterol) and their LAMA/LABA combination ('719+vilanterol). With the patent expiry of Advair in 2011 and the looming expiration of Symbicort later this year, GSK has positioned itself as the front runner in capturing a large share of the future respiratory market with these two strong Phase III FDC drug programs and plans to submit regulatory RELOVAIR applications for COPD in the US and Europe in mid-2012.  However, several competitors are riding on their heels, including Boehringer Ingelheim, Novartis, Almirall/Forest, and the up-and-coming Pearl Therapeutics, with strong FDC candidates in their pipelines.

"Pearl Therapeutics is only in planning stages for their Phase III FDC program and is certainly the underdog among the current competition, but their innovative PT003 product had stellar Phase II data at ATS and they announced plans for PT010, a triple combination therapy of LAMA (glycopyrrolate), LABA (formoterol fumarate), and an inhaled corticosteroid, in one of their presentations," comments Ms. Stacey. "They will be an exciting company to watch as competitors in the FDC respiratory market race cross the finish line for novel inhaled therapies in COPD."

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