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CMC Biologics and RuiYi Enter into an Agreement for Development of a Novel Anti-IL-6 Monoclonal Antibody
Date:5/14/2013

arket production. The Company's fully integrated services includes cell line development using its proprietary CHEF1® system, process and formulation development, and comprehensive analytical testing. CMC Biologics has fully segregated microbial fermentation and mammalian cell culture suites and offers stirred tank and perfusion production processes. To learn more, visit www.cmcbio.com.

CHEF1® Expression Technology Advantage
The CHEF1 expression system has been used extensively to create clinical production cell lines and has been approved for commercial production. The CHEF1 integrated expression platform accelerates development of cell lines for cGMP production by using robust procedures and reliable raw materials including chemically defined media, adapted CHO cells, and CHEF1 expression plasmids to produce high levels of recombinant protein in rapid timeframes.

About RuiYi
RuiYi is focused on the discovery and development of novel biologic therapeutics that meet the medical and commercial needs for China's patients and healthcare system and that have the potential to be disruptive globally. In addition to RYI-008, RuiYi has a growing pipeline of monoclonal antibodies from internal discovery efforts utilizing series of the Company's technologies, including the iCAP (intramembranous Conformation Antigen Presenting) system. Targets include a select subset of G protein coupled receptors (GPCR), where specificity in binding is critical but has proven difficult to achieve with small molecule modulators. RuiYi's executive management team has offices in La Jolla, California, and RuiYi's discovery efforts and research facility are located in in the Zhangjiang Hi-Tech Park in Pudong, Shanghai, China.  For more, visit www.ruiyibio.com.  
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SOURCE RuiYi Inc.; CMC Biologics
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