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CMC Biologics and RuiYi Enter into an Agreement for Development of a Novel Anti-IL-6 Monoclonal Antibody
Date:5/14/2013

SEATTLE, COPENHAGEN, Denmark and SHANGHAI, May 14, 2013 /PRNewswire/ -- CMC Biologics today announced the execution of an agreement with RuiYi Inc. to develop a cell line for RYI-008, a novel anti-IL-6 monoclonal antibody. CMC Biologics' proprietary CHEF1® high-productivity expression plasmid will be utilized for the cell line development to optimize cell growth, and consistent, high-level protein expression in a rapid time frame. Specific terms of the agreement were not disclosed.

"We are excited to work with CMC Biologics, a global contract manufacturing organization known for its technical excellence in biopharmaceutical development and cGMP manufacturing," said Paul Grayson , President and CEO of RuiYi. "The integrated services, including cell line development using the proprietary CHEF1 system, along with CMC's responsive and collaborative interactive style made CMC Biologics the obvious partner for this important global effort."

"We are pleased with the opportunity to build a long-term relationship with RuiYi on the development of RYI-008.  RYI-008 is an antibody with unprecedented potency and remarkable half-life, creating a significant opportunity to be a best in class product in the rapidly evolving field of IL-6 biology." said Mark Sawicki , PhD, Global Vice President Business Development of CMC Biologics. "This agreement underscores our strategic focus on biologics development in emerging markets."

About CMC Biologics
CMC Biologics is a dedicated contract biopharmaceutical manufacturing and development organization with facilities in Copenhagen, Denmark and Seattle, Washington, USA. CMC Biologics specializes in custom services for scale up and cGMP manufacture of protein-based therapeutics for preclinical, clinical trials, and in-m
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SOURCE RuiYi Inc.; CMC Biologics
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