Navigation Links
CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
Date:10/27/2008

find treatments that lead to a better overall quality of life."

In RAPID 1, patients treated with CIMZIA together with MTX reported gains in additional work and household work days per month and productive work and household work days per month as early as week 4. Over 6 months, improvements continued compared to the control group. These improvements were maintained for up to one year.

Additionally, data presented shows Health Reported Quality of Life Measurements (HRQoL) approached population norms in the "vitality" and "mental health" domains. As assessed by the Fatigue Assessment Scale of 1 to 10, patients in the trial also reported a mean reduction in fatigue to 3.1 points at week 100 with CIMZIA together with MTX treatment.

Notes to Editors:

RAPID Clinical Trials Program

The international, multi-center, double-blind placebo-controlled RAPID (RA PreventIon of structural Damage) clinical trials were designed to establish the efficacy and tolerability of CIMZIA(R) (certolizumab pegol) together with methotrexate (MTX) in the treatment of active rheumatoid arthritis who did not adequately respond to conventional treatment. The program is comprised of two large, international, multi-center placebo-controlled studies - RAPID 1 (027) and RAPID 2 (050).

In the year-long RAPID 1 trial, patients randomly received one of three treatment regimens: 393 patients received CIMZIA 400 mg at weeks 0, 2 and 4, then CIMZIA 200 mg together with MTX every two weeks; 390 patients received CIMZIA 400 mg together with MTX every 2 weeks; 199 patients received placebo together with MTX every 2 weeks. RAPID 1 met co-primary endpoints: ACR20 response rate(a) at week 24 and the change from baseline in mTSS(b) at week 52. An open-label extension study continued to evaluate the effects of CIMZIA over two years.

In the six-month RAPID 2 trial, 619 patients randomly received one of three treatment regimens: 246 patients received CIMZIA 400 mg at w
'/>"/>

SOURCE UCB
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohns Disease Patients
2. CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohns Patients
3. Cimzia(R) Provides Long-Term Efficacy with Stable Dosing in Crohns Disease
4. CIMZIA(R) (certolizumab pegol), Significantly Reduces Structural Damage and Rheumatoid Arthritis Signs & Symptoms for Up to One Year
5. Analysis of Long-Term Vicriviroc Data Provides Evidence of Sustained Viral Suppression, Increased CD4 Cell Counts and Tolerability in Treatment-Experienced HIV-Infected Patients
6. Rubicon Provides Genome Amplification for the Cancer Genome Atlas Project
7. IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following September Meeting of European Committee for Medicinal Products for Human Use (CHMP)
8. Fralex provides update on timing of interim analysis results
9. Vanda Pharmaceuticals Provides Update on Iloperidone
10. Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus
11. Study Reveals Novel LCD Solution Provides Significant Benefits Versus Calcipotriol In Treatment Of Moderate Psoriasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... , May 28, 2015 ... the addition of the "United States Medical ... to their offering.      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... in the United States ... Medical device manufacturers across the ...
(Date:5/28/2015)... Calif. , May 28, 2015 Isis ... webcast:What: , Akcea Therapeutics WebcastWhen: , Thursday, June 4 ... www.isispharm.com How: , Live on the Internet.  Simply ... unable to participate during the live event, a replay ... time at www.isispharm.com . ABOUT ISIS ...
(Date:5/28/2015)... 2015 The Parenteral Drug Association (PDA) ... organization of the Johnson & Johnson Kilmer Conference ... Johnson & Johnson (J&J) is reviving the ... in endoscopes. J&J ran 8 conferences on sterilization, ... 2003 on advances in sterilization and other topics. ...
Breaking Medicine Technology:United States Medical Adhesives Market Forecast and Opportunities, 2020 - New Medical Innovations with 3M, Henkel Adhesive Research, Ethicon and Cyberbond Dominating 2United States Medical Adhesives Market Forecast and Opportunities, 2020 - New Medical Innovations with 3M, Henkel Adhesive Research, Ethicon and Cyberbond Dominating 3Webcast Alert: Akcea Therapeutics Conference Call 2Webcast Alert: Akcea Therapeutics Conference Call 3PDA Announces Support for the Johnson & Johnson Kilmer Conference 2
(Date:5/29/2015)... (PRWEB) May 29, 2015 Red Hot ... the newest Red Hot & Blue restaurant at 525 New ... Thursday, May 7, 2015. “The Red Hot & Blue Restaurant ... 18 years, but we have moved to a new location ... in the middle of all the activities on the Promenade–with ...
(Date:5/29/2015)... RIDGELAND, Miss. (PRWEB) May 29, 2015 ... recently announced the graduates of its Advanced Training ... trains students, who fill roles in their health ... both the theory and methodology of continuous quality ... is a sister-program to Dr. Brent James’ internationally ...
(Date:5/29/2015)... Inspire Nexus, a new social network officially launching ... many life coaches have asked, "How do I find ... to become a credentialed Coach?" , Many Life and ... long. Inspire Nexus, a social network for Coaches provides ... have experience coaching a certain number of hours, qualify ...
(Date:5/29/2015)... 29, 2015 The campaign focuses on ... a number of specific concerns within, including the importance ... mental health in the workplace. We are encouraged to ... campaign also brings special focus to people living with ... up and seek help from healthcare professionals and their ...
(Date:5/29/2015)... 2015 The report “Muscle Spasm ... on the therapeutic development for Muscle Spasm. Spasms ... the body, leading to many different symptoms and ... new targets and MOAs to produce first-in-class and ... review of Axillary Hyperhidrosis with 19 market data ...
Breaking Medicine News(10 mins):Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 2Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 3Health News:Red Hot & Blue Restaurant Opens in Cary, North Carolina 4Health News:HORNE LLP’s Healthcare Delivery Institute Graduates Class from the Advanced Training Program 2Health News:Mediaplanet Brings Activism to Those Living with Mental Illness in Bew “Mental Health Awareness” Campaign 2Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 4
... parity insurance less likely to get timely outpatient care , , ... better share the burden of the cost for mental health ... up less of the bill, a new study says. , ... some of whose plans provided equal cost-sharing and others whose ...
... Clinical pharmacy services can significantly reduce the cost of ... care system, according to a new study by researchers ... every dollar spent by hospitals or health systems to ... drug costs, reductions in adverse drug events and medication ...
... , , TUESDAY, Dec. 23 (HealthDay News) -- As many ... States combine over-the-counter medications with prescription drugs in ways ... a new survey finds. , A recent report estimated ... emergency department visits for adverse drug reactions each year, ...
... and Human Services recently awarded Jefferson Hospital for Neuroscience ... organ donation conversion rate of 75 percent or greater ... given during the fourth National Learning Congress held in ... and staff at Jefferson Hospital for Neuroscience work tirelessly ...
... virtually a micro-camera, is a revolutionary diagnostic tool in diagnosing small ... GI tract, though the number of the images for the lesions ... reader still has to scan ten thousands of the images one ... lesions are in. So, it may be a big burden on ...
... of radiation therapy to treat cancer inevitably involves exposure ... have been well established, a number of patients experience ... These side effects related to inflammatory process cause discomfort ... treatment time. , A research article to be ...
Cached Medicine News:Health News:Psych Patients With Cost-Sharing Plans Use More Services 2Health News:Drug Combinations Putting Seniors at Risk 2Health News:Drug Combinations Putting Seniors at Risk 3Health News:Drug Combinations Putting Seniors at Risk 4Health News:Jefferson Hospital for Neuroscience receives Department of Health and Human Services award 2Health News:What is the mechanism of the chronic radiation enteritis? 2
The Oxoid Legionella Latex Test is a latex agglutination test for the identification of predominant Legionella species grown on plate media from patients with suspected Legionellosis or from environm...
... A revolutionary new agar plate for economically screening ... this biplate with the urine specimen. If the ... the chromogenic side of the biplate will 3 ... E. coli, the BluEcoli™ Urine Biplate is a ...
... The Trinity Biotech Captia™ Legionella ... (ELISA) is intended for the ... (IgG and IgM) to Legionella ... serum from patients with clinical ...
SDA is a patented isothermal amplification technology capable of generating billions of copies of target molecules from a single DNA or RNA template in just minutes....
Medicine Products: