Navigation Links
CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years
Date:10/27/2008

fessor of Medicine at the University of Colorado School of Medicine.

CIMZIA had a low occurrence of treatment discontinuation due to adverse events. The most commonly occurring adverse events were headache, nasopharyngitis, and upper respiratory tract infections. Pooled safety data from the two main phase III trials showed there was a low incidence of injection site burning and stinging (n=<3 new cases /100 patient-years) and a low level of discontinuations due to adverse events (AEs). Reported serious adverse reactions were infections (including tuberculosis) and malignancies (including lymphoma).

Additional data presented at ACR showed that patients who withdrew from RAPID 1 and 2 trials because they did not achieve an ACR20 response at Week 12 (confirmed at Week 14) nevertheless showed a slowed progression of structural damage within the joints as measured at Week 16 by analysis of radiographic data.

Additional data presented focused on the effect of treatment with CIMZIA together with MTX in quality of life measurements. In RAPID 1, nearly three-quarters of patients achieved improvements in physical function when treated with CIMZIA together with MTX, including 72.4 percent of those initially treated with CIMZIA 200 mg together with MTX or 70.1 percent of those treated with CIMZIA 400 mg together with MTX.

On a 10-point improvement on the Patients Assessment of Arthritis Pain (PAAP) scale, the data showed an average improvement of 39.1 and 38.1 points for those on CIMZIA 200 mg together with MTX and CIMZIA 400 mg together with MTX, respectively.

"It is exciting to see that these patients are deriving and maintaining improvements on multiple levels with continued CIMZIA treatment," noted Philip Mease, M.D., study investigator at the Seattle Rheumatology Associates and Director of Rheumatology Research at Swedish Medical Center. "Reducing pain and discomfort from RA is extremely important, but it is also noteworthy when patients
'/>"/>

SOURCE UCB
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohns Disease Patients
2. CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohns Patients
3. Cimzia(R) Provides Long-Term Efficacy with Stable Dosing in Crohns Disease
4. CIMZIA(R) (certolizumab pegol), Significantly Reduces Structural Damage and Rheumatoid Arthritis Signs & Symptoms for Up to One Year
5. Analysis of Long-Term Vicriviroc Data Provides Evidence of Sustained Viral Suppression, Increased CD4 Cell Counts and Tolerability in Treatment-Experienced HIV-Infected Patients
6. Rubicon Provides Genome Amplification for the Cancer Genome Atlas Project
7. IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following September Meeting of European Committee for Medicinal Products for Human Use (CHMP)
8. Fralex provides update on timing of interim analysis results
9. Vanda Pharmaceuticals Provides Update on Iloperidone
10. Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus
11. Study Reveals Novel LCD Solution Provides Significant Benefits Versus Calcipotriol In Treatment Of Moderate Psoriasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... NEW YORK , January 15, 2014 ... BreedIT Ltd., the exclusive worldwide distributor of highly sophisticated ... that on January 7, 2014, the Company,s board of ... Ben-Zion Weiner as its new member of the ...
(Date:1/15/2014)... 2014  Echo Therapeutics, Inc. (Nasdaq: ECTE ) ... System as a non-invasive, wireless continuous glucose monitoring system, ... Chairman and Interim CEO of Echo Therapeutics, will present ... Conference. Mr. Doman will make a ...
(Date:1/15/2014)... Pharmaceuticals International, Inc. (NYSE: VRX and ... the Hart-Scott-Rodino Antitrust Improvements Act of 1976 ("HSR") with ... indirect wholly-owned subsidiary, Sapphire Subsidiary Corp. ("Purchaser"), for all ... Medical, Inc. (NASDAQ: SLTM ) ("Solta") at ...
Breaking Medicine Technology:BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
... 2011 Reportlinker.com announces that a new market research ... Pain Therapeutics - Drugs, Markets and Companies ... report describes the latest concepts of pathomechanisms of pain ... pharmacotherapies for pain. Major segments of the pain market ...
... Pharmacotherapy research is set to become vastly more ... Wolters Kluwer Pharma Solutions , parent of the ... scientific information and analytics to professionals in the pharmaceutical and ... access (OA) publishing option for authors submitting original research articles ...
Cached Medicine Technology:Reportlinker Adds Pain Therapeutics - Drugs, Markets and Companies 2Reportlinker Adds Pain Therapeutics - Drugs, Markets and Companies 3Adis Journals Embrace Open Access 2Adis Journals Embrace Open Access 3Adis Journals Embrace Open Access 4
(Date:4/24/2014)... epidemic of prescription opioid overdose deaths was outlined yesterday ... by leaders of agencies in the U.S. Department of ... health care providers to expand their use of medications ... describes a number of misperceptions that have limited access ... how medications can be used in combination with behavior ...
(Date:4/24/2014)... has found a relationship between motor skill deficiencies and ... in very young children. , The findings, believed ... relationship between motor skills and autism severity, indicate that ... included in treatment plans for young children with autism, ... of Public Health and Human Sciences. , "Recognizing ...
(Date:4/23/2014)... Using frozen stool from healthy, unrelated donors was ... relapsing diarrhea caused by Clostridium difficile , ... Clinical Infectious Diseases and available online. ... equally effective whether given via a colonoscope or ... may make this promising treatment more readily available ...
(Date:4/23/2014)... to give exercise enthusiasts the extra nudge they need ... a cyber buddy can help. , The study, which ... is the first to indicate that although a human ... software-generated partner also can be effective. , "We wanted ... motivate people to give greater effort while exercising than ...
(Date:4/23/2014)... A novel compound that targets an important brain ... cocaine addiction behaviors, including relapse behavior, a University at ... strong evidence that this may be a novel lead ... medications exist., The UB research was published as an ... , In the study, the compound, RO5263397, severely blunted ...
Breaking Medicine News(10 mins):Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 2Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 3Health News:HHS leaders call for expanded use of medications to combat opioid overdose epidemic 4Health News:Motor skill deficiencies linked to autism severity in new research 2Health News:Pilot study suggests ways to widen access to fecal transplants for C. diff infections 2Health News:Cyber buddy is better than 'no buddy' 2Health News:Novel compound halts cocaine addiction and relapse behaviors 2
... be the cause, experts say , WEDNESDAY, May 26 (HealthDay ... older person,s condition. , The joint disease occurs over time ... allowing the bones to rub together and causing pain, swelling ... it,s like death and taxes -- you will likely get ...
... ... new member to its Board of Directors. The announcement was made by Jim Clarke, founder and ... ... a new member to its Board of Directors. The announcement was made by Jim Clarke, founder ...
... ... to health and beauty PR agency Robin Leedy & Associates (RL&A), helping to develop ... ... and beauty PR specialists Robin Leedy & Associates (RL&A) , a niche brand ...
... ... of their latest product Performance Canvas 2.2 as a mobile analytics ... 2.2 with Planning, the first fully unified Information Synthesis, Performance Management ... Sharepoint 2010 and SQL Analysis Services R2. The Performance Canvas Mobile ...
... ... are proud to team with the L.A. Dodger,s ThinkCure organization for "YAS-A-THON for ThinkCure," ... ... Fowler and her YAS Fitness Centers are proud to team with the L.A. Dodger,s ...
... ... Jones will take over as President of the company effective July 1st, 2010. , ... Waterloo, IA (Vocus) May 26, 2010 -- John Spragle ... retirement and VGM Insurance,s plan for my successor. Effective June 1, 2010, Tom Jones will be ...
Cached Medicine News:Health News:Osteoarthritis Claims Growing Number of Younger Victims 2Health News:Osteoarthritis Claims Growing Number of Younger Victims 3Health News:2 BigHearts Board Announces Addition to Board of Directors: Michael Unetich 2Health News:Robin Leedy & Associates Hires Digital Content Producer, Taking Social Media for Drugstore Brands Digital Capability to the Next Level 2Health News:Robin Leedy & Associates Hires Digital Content Producer, Taking Social Media for Drugstore Brands Digital Capability to the Next Level 3Health News:DSPanel's New Mobile Analytics Server for Business Intelligence: Data Analysis, Monitoring and Planning When and Where You Need It 2Health News:DSPanel's New Mobile Analytics Server for Business Intelligence: Data Analysis, Monitoring and Planning When and Where You Need It 3Health News:REBEL WITH A CAUSE: Kimberly Fowler and YAS Fitness Centers Roll with L.A. Dodgers to Cure Cancer 2Health News:REBEL WITH A CAUSE: Kimberly Fowler and YAS Fitness Centers Roll with L.A. Dodgers to Cure Cancer 3Health News:VGM Insurance President Passes the Baton 2
... The TC-PLUS Solution tricompartmental total knee prosthesis ... knee arthroplasty. State-of-the-art design and manufacturing technologies ... optimum biomechanical function as well as a ... tibial insert to keep wear to a ...
... Proven Knee System is a long term, ... design. Available in both posterior stabilized and ... Knee System provides the flexibility needed to ... and ease of identification keeps the user ...
... FluoroNav Virtual Fluoroscopy software ... Technologies has incorporated ease ... technology features such as ... three-dimensional models of image ...
... T.L.I.F. SG Instruments are the next evolution ... comprehensive and functionally sound instruments.. The T.L.I.F. ... disc removal and disc preparation instruments designed ... Excellent design, a wide range of instrument ...
Medicine Products: