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CHMP Recommends Approval of Cialis for the Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia
Date:9/21/2012

the treatment of erectile dysfunction or benign prostatic hyperplasia were headache, indigestion, back pain and muscle pain. They were transient and generally mild or moderate.

BPH is a condition in which the prostate enlarges, which can cause urinary symptoms like needing to go urgently and frequently.

ED is a condition in which the penis does not fill with enough blood to harden and expand when a man is sexually excited, or when he cannot keep an erection. Approximately 40 percent of men over 40 have ED.[1]

BPH and ED are conditions that may occur in the same patient. Several studies have shown that many men with ED also experience the symptoms of BPH.[2],[3],[4]

Tadalafil inhibits an enzyme called phosphodiesterase type 5 (PDE5). By inhibiting PDE5 in the penis, tadalafil helps produce vascular smooth muscle relaxation and increases blood flow. PDE5 enzymes are also found in the smooth muscle of the prostate and bladder. The mechanism for how tadalafil reduces BPH symptoms has not been fully established.   

About Tadalafil (Cialis)
Tadalafil is approved to treat erectile dysfunction (ED) in adult males throughout the world, including in the United States, Europe, Australia, Mexico and Canada. There are two different dosing options: tadalafil for once a day use (2.5 and 5 mg) or tadalafil for use as-needed, or 'on-demand' (10 mg and 20 mg).

Tadalafil on demand is a prescription only medicine licensed in the EU for the treatment of erectile dysfunction.

Tadalafil for once a day use is an ED treatment that is taken every day to help improve erectile function. When taken every day, it may help men be ready for sex anytime between doses or remove the need to plan the timing of sexual activity around taking a pill.

Tadalafil on demand may be taken at least 30 minutes  prior to sexual activity, with or withou
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SOURCE Eli Lilly and Company
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